Search Results - "Manon, LANCIEN"

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells by Menez, Virginie, Kergrohen, Thomas, Shasha, Tal, Silva-Evangelista, Claudia, Le Dret, Ludivine, Auffret, Lucie, Subecz, Chloé, Lancien, Manon, Ajlil, Yassine, Vilchis, Irma Segoviano, Beccaria, Kévin, Blauwblomme, Thomas, Oberlin, Estelle, Grill, Jacques, Castel, David, Debily, Marie-Anne

“…We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the…”
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DIPG-43. CHARACTERIZATION OF THE BLOOD BRAIN BARRIER IN DIPG MURINE MODELS AND EFFECT OF ULTRASOUND ON ITS SPECIFICITIES AND PERMEABILITY TO ASIDNA by BIARD, adam, LE Ludivine, DRET, Marie, DUTREIX, Alexandre, CARPENTIER, Manon, LANCIEN, Alexandre, PELLISSIER, Marie-Anne, Debily, David, CASTEL, Jacques, GRILL, Kevin, BECCARIA

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First insights in the pharmacodynamics of mamba toxins, promising therapeutic candidates to treat kidney cysts by inhibition of vasopressin type 2 receptor by Droctove, Laura, Lancien, Manon, Mourier, Gilles, Servent, Denis, Gilles, Nicolas

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Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling by Bruschi, Marco, Midjek, Lilia, Ajlil, Yassine, Vairy, Stephanie, Lancien, Manon, Ghermaoui, Samia, Kergrohen, Thomas, Verreault, Maite, Idbaih, Ahmed, de Biagi, Carlos Alberto Oliveira, Liu, Ilon, Filbin, Mariella G, Beccaria, Kevin, Blauwblomme, Thomas, Puget, Stephanie, Tauziede-Espariat, Arnault, Varlet, Pascale, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Le Teuff, Gwenael, Grill, Jacques, Montagnac, Guillaume, Elkhatib, Nadia, Debily, Marie-Anne, Castel, David

“…Abstract Background Diffuse midline gliomas (DMG) are pediatric tumors with negligible 2-year survival after diagnosis characterized by their ability to…”
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A new Kunitz‐type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor by Droctové, Laura, Ciolek, Justyna, Mendre, Christiane, Chorfa, Amélia, Huerta, Paola, Carvalho, Chrystelle, Gouin, Charlotte, Lancien, Manon, Stanajic‐Petrovic, Goran, Braco, Lorine, Blanchet, Guillaume, Upert, Gregory, De Pauw, Gregory, Barbe, Peggy, Keck, Mathilde, Mourier, Gilles, Mouillac, Bernard, Denis, Servent, Rodríguez de la Vega, Ricardo C., Quinton, Loïc, Gilles, Nicolas

“…Background and Purpose Venomous animals express numerous Kunitz‐type peptides. The mambaquaretin‐1 (MQ1) peptide identified from the Dendroaspis angusticeps…”
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DIPG-38. PATIENT-DERIVED THREE-DIMENSIONAL AVATARS REVEAL CELL-AUTONOMOUS MECHANISMS DRIVING INVASION AND METASTATIC PROGRESSION IN DIFFUSE MIDLINE GLIOMAS by Bruschi, Marco, Midjek, Lilia, Ajlil, Yassine, Vairy, Stephanie, Lancien, Manon, Ghermaoui, Samia, Kergrohen, Thomas, Verreault, Maïté, Idbaih, Ahmed, Beccaria, Kévin, Blauwblomme, Thomas, Puget, Stéphanie, Tauziede-Espariat, Arnault, Varlet, Pascale, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Teuff, Gwenael Le, Grill, Jacques, Montagnac, Guillaume, Elkhatib, Nadia, Debily, Marie-Anne, Castel, David

“…Diffuse midline gliomas H3K27-altered are pediatric tumors associated with dismal survival after diagnosis that are characterized by their ability to…”
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Crystal structure and functional domains of the Mambaquaretin-1, a vasopressin type 2 receptor peptide inhibitor for kidney cysts treatment by Droctové, Laura, Ciolek, Justyna, Lancien, Manon, Stura, Enrico A., Vera, Laura, Floquet, Nicolas, Witzgall, Ralph, Mouillac, Bernard, Mendre, Christiane, Mourier, Gilles, Servent, Denis, Gilles, Nicolas

“…Mambaquaretins are a group of toxins from mamba venoms, containing seven members until now, which target the vasopressin type 2 receptor (V2R). V2R, primarily…”
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A snake toxin as a theranostic agent for the type 2 vasopressin receptor by Droctové, Laura, Lancien, Manon, Tran, Vu Long, Susset, Michaël, Jego, Benoit, Theodoro, Frederic, Kessler, Pascal, Mourier, Gilles, Robin, Philippe, Diarra, Sékou Siramakan, Palea, Stefano, Flahault, Adrien, Chorfa, Amélia, Corbani, Maithé, Llorens-Cortes, Catherine, Mouillac, Bernard, Mendre, Christiane, Pruvost, Alain, Servent, Denis, Truillet, Charles, Gilles, Nicolas

“…MQ1, a snake toxin which targets with high nanomolar affinity and absolute selectivity for the type 2 vasopressin receptor (V2R), is a drug candidate for renal…”
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Abstract 154: Diffuse midline glioma invasion and metastasis rely on cell-autonomous signaling through a phenotypic switch controlled by BMP7 by Bruschi, Marco, Midjek, Lilia, Ajlil, Yassine, Vairy, Stephanie, Lancien, Manon, Ghermaoui, Samia, Kergrohen, Thomas, Verreault, Maite, Idbaih, Ahmed, de Biagi, Carlos Alberto Oliveira, Liu, Ilon, Filbin, Mariella G., Beccaria, Kevin, Blauwblomme, Thomas, Puget, Stephanie, Tauziede-Espariat, Arnault, Varlet, Pascale, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Le Teuff, Gwenael, Grill, Jacques, Montagnac, Guillaume, Elkathib, Nadia, Debily, Marie-Anne, Castel, David

“…Diffuse midline gliomas (DMG) are pediatric tumors with negligible two-year survival after diagnosis characterized by their ability to infiltrate the central…”
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A snake toxin as a theranostic agent for the type 2 vasopressin receptor by Droctové, Laura, Lancien, Manon, Tran, Vu Long, Susset, Michaël, Jego, Benoit, Theodoro, Frederic, Kessler, Pascal, Mourier, Gilles, Robin, Philippe, Diarra, Sékou Siramakan, Palea, Stefano, Flahault, Adrien, Chorfa, Amélia, Corbani, Maithé, Llorens-Cortes, Catherine, Mouillac, Bernard, Mendre, Christiane, Pruvost, Alain, Servent, Denis, Truillet, Charles, Gilles, Nicolas

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