Search Results - "Manoj, Sharmila"

Different receptors binding to distinct interfaces on herpes simplex virus gD can trigger events leading to cell fusion and viral entry by Spear, Patricia G., Manoj, Sharmila, Yoon, Miri, Jogger, Cheryl R., Zago, Anna, Myscofski, Dawn

“…One of the herpes simplex virus envelope glycoproteins, designated gD, is the principal determinant of cell recognition for viral entry. Other viral…”
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Water Channel in the Binding Site of a High Affinity Anti-Methotrexate Antibody by Gayda, Susan, Longenecker, Kenton L, Manoj, Sharmila, Judge, Russell A, Saldana, Sylvia C, Ruan, Qiaoqiao, Swift, Kerry M, Tetin, Sergey Y

“…In the present study, we report the structure of the free and drug-bound Fab fragment of a high affinity anti-methotrexate antibody and perform a thermodynamic…”
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Mutations in Herpes Simplex Virus Glycoprotein D That Prevent Cell Entry Via Nectins and Alter Cell Tropism by Manoj, Sharmila, Jogger, Cheryl R., Myscofski, Dawn, Yoon, Miri, Spear, Patricia G.

“…Glycoprotein D (gD) determines which cells can be infected by herpes simplex virus (HSV) by binding to one of the several cell surface receptors that can…”
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Approaches to Enhance the Efficacy of DNA Vaccines by Manoj, Sharmila, Babiuk, Lorne A., den Hurk, Sylvia

“…ABSTRACT DNA vaccines consist of antigen-encoding bacterial plasmids that are capable of inducing antigen-specific immune responses upon inoculation into a…”
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Modulation of immune responses to bovine herpesvirus‐1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154 by Manoj, Sharmila, Griebel, Philip J., Babiuk, Lorne A., Van Drunen Littel‐Van Den Hurk, Sylvia

“…Summary The objective of this study was to determine whether a DNA vaccine encoding bovine CD154 linked to a truncated version of bovine herpesvirus‐1 (BHV‐1)…”
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Three‐dimensional structure, binding, and spectroscopic characteristics of the monoclonal antibody 43.1 directed to the carboxyphenyl moiety of fluorescein by Gayda, Susan, Longenecker, Kenton L., Judge, Russell A., Swift, Kerry M., Manoj, Sharmila, Linthicum, D. Scott, Tetin, Sergey Y.

“…ABSTRACT Unlike other known anti‐fluorescein antibodies, the monoclonal antibody 43.1 is directed toward the fluorescein's carboxyl phenyl moiety. It…”
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Targeting with Bovine CD154 Enhances Humoral Immune Responses Induced by a DNA Vaccine in Sheep by Manoj, Sharmila, Griebel, Philip J, Babiuk, Lorne A, van Drunen Littel-van den Hurk, Sylvia

“…CD40-CD154 interactions play an important role in regulating humoral and cell-mediated immune responses. Recently, these interactions have been exploited for…”
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Different receptors binding to distinct interfaces on herpes simplex virus gD can trigger events leading to cell fusion and viral entry by Spear, Patricia G., Manoj, Sharmila, Yoon, Miri, Jogger, Cheryl R., Zago, Anna, Myscofski, Dawn

“…One of the herpes simplex virus envelope glycoproteins, designated gD, is the principal determinant of cell recognition for viral entry. Other viral…”
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Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses by Manoj, Sharmila, Babiuk, Lorne A, van Drunen Littel-van den Hurk, Sylvia

“…As an approach to create a divalent DNA vaccine, a truncated secreted version of bovine herpesvirus-1 (BHV-1) glycoprotein D (tgD) and the amino-terminal…”
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Strategies to enhance the efficacy of DNA vaccines by Manoj, Sharmila

“…Bovine herpesvirus-1 (BHV-1) causes respiratory and genital infections in cattle. Several vaccines have been developed to prevent virus induced disease…”
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Immunization with a dicistronic plasmid expressing a truncated form of bovine herpesvirus-1 glycoprotein D and the amino-terminal subunit of glycoprotein B results in reduced gB-specific immune responses☆☆This article is published as VIDO Journal Series 331 by Manoj, Sharmila, Babiuk, Lorne A, van Drunen Littel-van den Hurk, Sylvia

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