Search Results - "Manoharan, M"

Estimation of stress-strength reliability in s-out-of-k system for new flexible exponential distribution under progressive type-II censoring by Chandran, Greeshma, Manoharan, M.

“…This article addresses stress-strength reliability estimation in s-out-of-k systems under progressive type-II censoring.  The system consists of components…”
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Estimation of stress-strength reliability using discrete phase type distribution by Jose, Joby K., M., Drisya, M., Manoharan

“…In this paper, the stress-strength reliability of single and multi-component systems are estimated assuming discrete phase type distribution for stress and…”
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Impact of the COVID-19 pandemic on maternal mental heath by Rose, E., Manoharan, M., Powell, J.

“…Introduction As countries adopt strict quarantines and lockdowns, increasing attention has been given to the impact on mental wellbeing. The influence of this…”
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Therapeutic Silencing of Mutant Huntingtin with siRNA Attenuates Striatal and Cortical Neuropathology and Behavioral Deficits by DiFiglia, M., Sena-Esteves, M., Chase, K., Sapp, E., Pfister, E., Sass, M., Yoder, J., Reeves, P., Pandey, R. K., Rajeev, K. G., Manoharan, M., Sah, D. W. Y., Zamore, P. D., Aronin, N.

“…Huntington's disease (HD) is a neurodegenerative disorder caused by expansion of a CAG repeat in the huntingtin (Htt) gene. HD is autosomal dominant and, in…”
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siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes by Matsuda, Shigeo, Keiser, Kristofer, Nair, Jayaprakash K, Charisse, Klaus, Manoharan, Rajar M, Kretschmer, Philip, Peng, Chang G, V. Kel’in, Alexander, Kandasamy, Pachamuthu, Willoughby, Jennifer L.S, Liebow, Abigail, Querbes, William, Yucius, Kristina, Nguyen, Tuyen, Milstein, Stuart, Maier, Martin A, Rajeev, Kallanthottathil G, Manoharan, Muthiah

“…Asialoglycoprotein receptor (ASGPR) mediated delivery of triantennary N-acetylgalactosamine (GalNAc) conjugated short interfering RNAs (siRNAs) to hepatocytes…”
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4′‑C‑Methoxy-2′-deoxy-2′-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing by Malek-Adamian, Elise, Guenther, Dale C, Matsuda, Shigeo, Martínez-Montero, Saúl, Zlatev, Ivan, Harp, Joel, Burai Patrascu, Mihai, Foster, Donald J, Fakhoury, Johans, Perkins, Lydia, Moitessier, Nicolas, Manoharan, Rajar M, Taneja, Nate, Bisbe, Anna, Charisse, Klaus, Maier, Martin, Rajeev, Kallanthottathil G, Egli, Martin, Manoharan, Muthiah, Damha, Masad J

“…We designed novel 4′-modified 2′-deoxy-2′-fluorouridine (2′-F U) analogues with the aim to improve nuclease resistance and potency of therapeutic siRNAs by…”
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Performance evaluation of mechanical and durability properties of self-compacting concrete replaced with nano-mineral additives by Manoharan, M., Sivakumar, Vidhya Lakshmi, Saranyasri, E., Dhanasekaran, N.

“…This research looks on the effectiveness of using nano-mineral admixtures in place of some cement for making self-compacting concrete (SCC). The goal is to…”
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Mycorrhizal Symbiotic Efficiency on C3 and C4 Plants under Salinity Stress - A Meta-Analysis by Chandrasekaran, Murugesan, Kim, Kiyoon, Krishnamoorthy, Ramasamy, Walitang, Denver, Sundaram, Subbiah, Joe, Manoharan M, Selvakumar, Gopal, Hu, Shuijin, Oh, Sang-Hyon, Sa, Tongmin

“…A wide range of C3 and C4 plant species could acclimatize and grow under the impact of salinity stress. Symbiotic relationship between plant roots and…”
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Validation of Patient Satisfaction Scale and Measurement of Patient Satisfaction Level Among Inpatient of a Tertiary Care Hospital, Chengalpattu District Tamil Nadu by R, Ranjana, VV Anantharaman, Palanisamy, Kaveri, K Bincy, M, Manoharan

“…Background: Patient satisfaction is crucial for research, administration, and planning. Since it reveals the effectiveness of the provider, customer happiness…”
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Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5′‑C‑Methyl Pyrimidine-Modified Oligonucleotides by Kel′in, Alexander V, Zlatev, Ivan, Harp, Joel, Jayaraman, Muthusamy, Bisbe, Anna, O′Shea, Jonathan, Taneja, Nate, Manoharan, Rajar M, Khan, Saeed, Charisse, Klaus, Maier, Martin A, Egli, Martin, Rajeev, Kallanthottathil G, Manoharan, Muthiah

“…Although judicious use of chemical modifications has contributed to the success of nucleic acid therapeutics, poor systemic stability remains a major hurdle…”
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Biodentine as BioRoot Inlay: A Case Report by Kamatchi, Mohanraj, Thiyagarajan, Gayatrikumary, Manoharan, M, Veerabadhran, Mahesh Mathian, Murugesan, Gawthaman, Vinodh, S

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The interfacial strength of carbon nanofiber epoxy composite using single fiber pullout experiments by Manoharan, M P, Sharma, A, Desai, A V, Haque, M A, Bakis, C E, Wang, K W

“…Carbon nanotubes and nanofibers are extensively researched as reinforcing agents in nanocomposites for their multifunctionality, light weight and high…”
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Beta half logistic distribution - A new probability model for lifetime data by Jose, Joby K., Manoharan, M.

“…Introducing a new flexible model for lifetimes called Beta half Logistic distribution by compounding the Beta distribution and half logistic distributions, we…”
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Intravesical therapy for urothelial carcinoma of the bladder by Manoharan, M

“…Transurethral resection is an effective therapy for non-muscle-invasive bladder cancer. However, the high rates of recurrence and significant risk of…”
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Can nomograms improve our ability to select candidates for active surveillance for prostate cancer? by Iremashvili, V, Manoharan, M, Parekh, D J, Punnen, S

“…Background: Our goal was to compare the ability of active surveillance (AS) criteria and preoperative nomograms to identify patients with pathologically…”
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Managing hyperglycaemia in patients with diabetes on enteral nutrition: the role of a specialized diabetes team by Wong, V W, Manoharan, M, Mak, M

“…Background/objectives: Hyperglycaemia is commonly observed in patients with diabetes mellitus (DM) while receiving enteral nutrition (EN) in hospital, and…”
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Quantitative Analysis of Parotid Sparing and Reducing Xerostomia Using Volumetric Modulated Arc Therapy in Oral Cancer Patients by PALANIVELU D, Mohandass P, Debashis Panda, Narendra Kumar Bhalla, KHANNA D, Susan Abharam, abhishek Puri, Manoharan M

“…Introduction: In head and neck cancer (HNC) radiotherapy, parotid, submandibular, and minor salivary glands are often incidentally irradiated. Hence,…”
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Accuracy of single-photon emission computed tomography in differentiating frontotemporal dementia from Alzheimer’s disease by McNeill, R, Sare, G M, Manoharan, M, Testa, H J, Mann, D M A, Neary, D, Snowden, J S, Varma, A R

“…Background: Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are the commonest causes of presenile dementia. In the absence of a biological marker,…”
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Effect of newer antioxidants on the bond strength of composite on bleached enamel by Manoharan, M, Shashibhushan, K, Poornima, P, Naik, Sathyajith, Patil, Disha, Shruthi, A

“…Aim: The study aims to evaluate the effect of the application of two antioxidants on the bond strength of composite resin to bleached enamel. Materials and…”
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Modulation of thermal stability can enhance the potency of siRNA by Addepalli, Haripriya, Meena, Peng, Chang G, Wang, Gang, Fan, Yupeng, Charisse, Klaus, Jayaprakash, K Narayanannair, Rajeev, Kallanthottathil G, Pandey, Rajendra K, Lavine, Gary, Zhang, Ligang, Jahn-Hofmann, Kerstin, Hadwiger, Philipp, Manoharan, Muthiah, Maier, Martin A

“…During RNA-induced silencing complex (RISC) assembly the guide (or antisense) strand has to separate from its complementary passenger (or sense) strand to…”
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