Search Results - "Mannozzi, Joseph"

Hemodynamic responses to handgrip and metaboreflex activation are exaggerated in individuals with metabolic syndrome independent of resting blood pressure, waist circumference, and fasting blood glucose by Stavres, Jon, Aultman, Ryan A., Brandner, Caleb F., Newsome, Ta’Quoris A., Vallecillo-Bustos, Anabelle, Wise, Havens L., Henderson, Alex, Stanfield, Diavion, Mannozzi, Joseph, Graybeal, Austin J.

“…Introduction: Prior studies report conflicting evidence regarding exercise pressor and metaboreflex responses in individuals with metabolic syndrome (MetS)…”
Get full text

Neural Control of Cardiovascular Function During Exercise in Hypertension by Dombrowski, Maryetta, Mannozzi, Joseph, O'Leary, Donal S

“…During both static and dynamic exercise hypertensive subjects can experience robust increases in arterial pressure to such an extent that heavy exercise is…”
Get full text

Ventricular-Vascular Uncoupling in Heart Failure: Effects of Arterial Baroreflex-Induced Sympathoexcitation at Rest and During Exercise by Mannozzi, Joseph, Al-Hassan, Mohamed-Hussein, Kaur, Jasdeep, Lessanework, Beruk, Alvarez, Alberto, Massoud, Louis, Bhatti, Tauheed, O'Leary, Donal S

“…Autonomic alterations in blood pressure are primarily a result of arterial baroreflex modulation of systemic vascular resistance and cardiac output on a…”
Get full text

Arterial Baroreflex Inhibits Muscle Metaboreflex Induced Increases in Effective Arterial Elastance: Implications for Ventricular-Vascular Coupling by Mannozzi, Joseph, Kim, Jong-Kyung, Sala-Mercado, Javier A, Al-Hassan, Mohamed-Hussein, Lessanework, Beruk, Alvarez, Alberto, Massoud, Louis, Bhatti, Tauheed, Aoun, Kamel, O'Leary, Donal S

“…The ventricular-vascular relationship assesses the efficacy of energy transferred from the left ventricle to the systemic circulation and is quantified as the…”
Get full text

Mechanisms mediating muscle metaboreflex control of cardiac output during exercise: Impaired regulation in heart failure by O'Leary, Donal S, Mannozzi, Joseph

“…The ability to increase cardiac output during dynamic exercise is paramount for the ability to maintain workload performance. Reflex control of the…”
Get full text

Baroreceptor Unloading at Rest and During Exercise in Heart Failure Exacerbates Ventricular‐Vascular Coupling by Mannozzi, Joseph, Kaur, Jasdeep, Al‐Hassan, Mohamed, O'Leary, Donal

“…The arterial baroreflex is the primary reflex controlling arterial blood pressure on a beat‐by‐beat basis via modulation of autonomic output to change cardiac…”
Get full text

Sympathetic Activity and Diastolic Dysfunction in HFrEF: Muscle metaboreflex induced changes in left ventricle passive filling pressure by Mannozzi, Joseph, Aoun, Kamel, Al-Hassan, Mohamed, Alvarez, Alberto, Lessanework, Beruk, Chung, Charles, O'Leary, Donal

“…Abstract only During exercise, activation of afferents within active skeletal muscle improves cardiovascular performance through reflex increases in cardiac…”
Get full text

Muscle metaboreflex stimulates the cardiac sympathetic afferent reflex causing positive feedback amplification of sympathetic activity: effect of heart failure by Mannozzi, Joseph, Senador, Danielle, Kaur, Jasdeep, Gross, Matthew, McNitt, Megan, Alvarez, Alberto, Lessanework, Beruk, O'Leary, Donal S

“…Exercise intolerance is a hallmark symptom of heart failure and to a large extent stems from reductions in cardiac output that occur due to the inherent…”
Get more information

Is The Muscle Metaboreflex Active During Blood Flow Restriction Training?: 390 by Mannozzi, Joseph Thomas, Al-Hassan, Mohamed-Hussein, Kaur, Jasdeep, Lessanework, Beruk, Alvarez, Alberto, Massoud, Louis, Aoun, Kamel, Spranger, Marty, O'Leary, Donal S.

Get full text

Chronic ablation of TRPV1-sensitive skeletal muscle afferents attenuates the muscle metaboreflex by Mannozzi, Joseph, Al-Hassan, Mohamed-Hussein, Lessanework, Beruk, Alvarez, Alberto, Senador, Danielle, O'Leary, Donal S

“…Exercise intolerance is a hallmark symptom of cardiovascular disease and likely occurs via enhanced activation of muscle metaboreflex-induced vasoconstriction…”
Get more information

Chronic Ablation of Hindlimb Afferents Containing TRPV1 Receptors Attenuates Cardiovascular Responses to Muscle Metaboreflex Activation by Mannozzi, Joseph Thomas, Senador, Danielle, Al-Hassan, Mohamed, Lessanework, Beruk, Alvarez, Alberto, O’Leary, Donal S.

“…Abstract only Increases in sympathetic nerve activity during exercise occur, in part, due to activation of the muscle metaboreflex – a pressor reflex triggered…”
Get full text

Hypertension depresses arterial baroreflex control of both heart rate and cardiac output during rest, exercise, and metaboreflex activation by O'Leary, Donal S, Mannozzi, Joseph, Augustyniak, Robert A, Ichinose, Masashi, Spranger, Marty D

“…Rapid regulation of arterial blood pressure on a beat-by-beat basis occurs primarily via arterial baroreflex control of cardiac output (CO) via rapid changes…”
Get more information

Ventricular contraction and relaxation rates during muscle metaboreflex activation in heart failure: are they coupled? by Mannozzi, Joseph, Massoud, Louis, Kaur, Jasdeep, Coutsos, Matthew, O'Leary, Donal S.

“…New Findings What is the central question of this study? Does the muscle metaboreflex affect the ratio of left ventricular contraction/relaxation rates and…”
Get full text

Blood flow restriction training activates the muscle metaboreflex during low-intensity sustained exercise by Mannozzi, Joseph, Al-Hassan, Mohamed-Hussein, Kaur, Jasdeep, Lessanework, Beruk, Alvarez, Alberto, Massoud, Louis, Aoun, Kamel, Spranger, Marty, O'Leary, Donal S

“…Blood flow restriction training (BFRT) employs partial vascular occlusion of exercising muscle and has been shown to increase muscle performance while using…”
Get full text

Muscle Metaboreflex Induced Increases in Effective Arterial Elastance by Mannozzi, Joseph T, Al‐Hassan, Mohamed, Lessanework, Beruk B, Alvarez, Alberto, O'Leary, Donal S

“…Dynamic exercise elicits robust changes in sympathetic activity in part due to accumulation of metabolites within the active skeletal muscle which activates…”
Get full text

Causes and Potential Treatment for Altered Muscle Metaboreflex Control of Ventricular Vascular Interactions in Heart Failure by Mannozzi, Joseph

“…Muscle Metaboreflex Activation occurs as a result of metabolic accumulation within active skeletal muscle that stimulates type III and IV afferents. This…”
Get full text

Arterial Baroreceptor Denervation Enhances Muscle Metaboreflex Induced Increases in Effective Arterial Elastance Without Worsening Stoke Work During Dynamic Exercise in Heart Failure by Mannozzi, Joseph, Kim, Jong‐Kyung, Al‐Hassan, Mohamed‐Hussein, Lessanework, Beruk, Alvarez, Alberto, Massoud, Louis, Bhatti, Tauheed, Aoun, Kamel, O'Leary, Donal S.

“…Optimal energy transfer from the left ventricle to the systemic circulation is paramount to the maintenance of workload performance during exercise. This…”
Get full text

Muscle metaboreflex-induced increases in effective arterial elastance: effect of heart failure by Mannozzi, Joseph, Kaur, Jasdeep, Spranger, Marty D, Al-Hassan, Mohamed-Hussein, Lessanework, Beruk, Alvarez, Alberto, Chung, Charles S, O'Leary, Donal S

“…Dynamic exercise elicits robust increases in sympathetic activity in part due to muscle metaboreflex activation (MMA), a pressor response triggered by…”
Get more information

Augmented sympathoexcitation slows postexercise heart rate recovery by Boyes, Natasha G, Mannozzi, Joseph, Rapin, Nicole, Alvarez, Alberto, Al-Hassan, Mohamed-Hussein, Lessanework, Beruk, Lahti, Dana S, Olver, T Dylan, O'Leary, Donal S, Tomczak, Corey R

“…Slow heart rate recovery following exercise may be influenced by persistent sympathoexcitation. This study examined ) the effect of muscle metaboreflex…”
Get full text

A cross‐species validation of single‐beat metrics of cardiac contractility by Ahmadian, Mehdi, Williams, Alexandra M., Mannozzi, Joseph, Konecny, Filip, Hoiland, Ryan L., Wainman, Liisa, Erskine, Erin, Duffy, Jennifer, Manouchehri, Neda, So, Kitty, Tauh, Keerit, Sala‐Mercado, Javier A., Shortt, Katelyn, Fisk, Shera, Kim, Kyoung‐Tae, Streijger, Femke, Foster, Glen E., Kwon, Brian K., O'Leary, Donal S., West, Christopher R.

“…The assessment of left ventricular (LV) contractility in animal models is useful in various experimental paradigms, yet obtaining such measures is inherently…”
Get full text