Imaging and Nanomedicine for Diagnosis and Therapy in the Central Nervous System: Report of the Eleventh Annual Blood-Brain Barrier Disruption Consortium Meeting

The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. The Eleventh Annual Blood-Brain Barrier Disruption Consortium Meeting was convened to discuss recent advances and future directions in imaging and nanom...

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Bibliographic Details
Published in:	AJNR. American journal of neuroradiology Vol. 27; no. 3; pp. 715 - 721
Main Authors:	Muldoon, L.L, Tratnyek, P.G, Jacobs, P.M, Doolittle, N.D, Christoforidis, G.A, Frank, J.A, Lindau, M, Lockman, P.R, Manninger, S.P, Qiang, Y, Spence, A.M, Stupp, S.I, Zhang, M, Neuwelt, E.A
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Oak Brook, IL Am Soc Neuroradiology 01-03-2006 American Society of Neuroradiology
Subjects:	Biological and medical sciences Blood-Brain Barrier Cardiovascular system Central Nervous System Diseases - diagnosis Central Nervous System Diseases - therapy Diagnostic Imaging Eye Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Nanomedicine Nervous system Radiodiagnosis. Nmr imagery. Nmr spectrometry Radionuclide investigations Special Report Nervous system diseases Treatment Radiodiagnosis Central nervous system Diagnosis Blood brain barrier Encephalon
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Summary:	The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. The Eleventh Annual Blood-Brain Barrier Disruption Consortium Meeting was convened to discuss recent advances and future directions in imaging and nanomedicine. Two sessions, one on Cell and Molecular Imaging in the CNS and another on Nanotechnology, Nanobiology, and Nanomedicine, were held March 17-18, 2005, in Portland, Ore. CNS imaging presentations targeted differentiating tumor, neural lesions, and necrosis from healthy brain tissue; methods of delivery of imaging agents across the BBB; and new iron oxide-based nanoparticle contrast agents for MR imaging. Nanobiology presentations covered the development of new nanotechnology and its use in imaging, diagnosis, and therapy in the CNS. Discussions at this meeting stressed the role of biotechnology in the convergence of CNS imaging and nanomedicine and are summarized in this article.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 content type line 25 ObjectType-Conference-1 SourceType-Conference Papers & Proceedings-1
ISSN:	0195-6108 1936-959X 1432-1920