Search Results - "Manning, W. B"

Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora by HARRIS, B. E, MANNING, B. W, FEDERLE, T. W, DIASIO, R. B

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Metabolism of the benzidine-based azo dye Direct Black 38 by human intestinal microbiota by MANNNG, B. W, CERNIGLIA, C. E, FEDERLE, T. W

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CEDIA, a new homogeneous immunoassay system by Henderson, D R, Friedman, S B, Harris, J D, Manning, W B, Zoccoli, M A

“…Genetic engineering of beta-galactosidase (EC 3.2.1.23) has led to the development of a new homogeneous assay system, CEDIA. The Z gene of the lac operon of…”
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Metabolism of 6-nitrochrysene by intestinal microflora by MANNING, B. W, CAMPBELL, W. L, FRANKLIN, W, DELCLOS, K. B, CERNIGLIA, C. E

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Drug metabolizing enzyme changes after chronic buthionine sulfoximine exposure modify acetaminophen disposition in rats by Manning, B W, Franklin, M R, Galinsky, R E

“…This study examined the effects of prolonged exposure to buthionine sulfoximine (BSO) on 1) the overall elimination pharmacokinetics of acetaminophen; 2) the…”
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Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs by Thornton-Manning, J R, Nichols, W K, Manning, B W, Skiles, G L, Yost, G S

“…3-Methylindole (3MI), a fermentation product of tryptophan produced by intestinal and ruminal microflora, has been shown to cause pneumotoxicity in several…”
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N-benzylimidazole-mediated changes in hepatic drug-metabolizing enzyme activities in Ah-responsive and Ah-non-responsive mice by Manning, B W, Franklin, M R

“…1. The inductive effect of N-benzylimidazole (NBI) on hepatic microsomal and cytosolic drug-metabolizing enzyme activities in aryl hydrocarbon (Ah)-responsive…”
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Effects of benzene metabolites on receptor-mediated phagocytosis and cytoskeletal integrity in mouse peritoneal macrophages by Manning, B W, Adams, D O, Lewis, J G

“…Exposure to benzene can induce a number of hematotoxicities and decrease host resistance to microorganisms and tumors. Several studies have shown that…”
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Induction of rat UDP-glucuronosyltransferase and glutathione S-transferase activities by L-buthionine-S,R-sulfoximine without induction of cytochrome P-450 by Manning, B W, Franklin, M R

“…The effect of prolonged exposure to buthionine sulfoximine (BSO) on rat hepatic Phase I and Phase II drug-metabolizing enzymes has been examined. Exposure to…”
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Potent carcinogenicity of nitrosodiethanolamine in rats by Lijinsky, W, Reuber, M. D, Manning, W. B

“…Nitrosodiethanolamine is found in synthetic cutting oils and in many cosmetic preparations and is probably the N-nitroso compound to which human exposure is…”
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An on-site immunoassay for detecting PCB in soil by Mapes, J.P. (EnSys, Inc., Research Triangle Park, NC), McKenzie, K.D, Stewart, T.N

“…The authors have developed a chromogenic immunoassay for PCB that is rapid, simple, sensitive, and cost effective. The test can be performed in the field,…”
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Changes in conjugative enzyme activity and acetaminophen metabolism in young and senescent male F-344 rats following prolonged exposure to buthionine sulfoximine by Galinsky, R E, Manning, B W, Kimura, R E, Franklin, M R

“…This study examined how advanced age affects glucuronide and sulfate conjugation of acetaminophen after prolonged exposure to L-buthionine-S,R-sulfoximine…”
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Mutagenic activation of the benzidine-based dye direct black 38 by human intestinal microflora by Cerniglia, C E, Zhuo, Z, Manning, B W, Federle, T W, Heflich, R H

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Gas-liquid chromatographic separation of bile acids and steroids on a nematic liquid crystal by Janini, G M, Manning, W B, Zielinski, Jr, W L, Muschik, G M

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Biotransformation of 1-nitropyrene to 1-aminopyrene and N-formyl-1-aminopyrene by the human intestinal microbiota by Manning, B W, Cerniglia, C E, Federle, T W

“…The nitropolycyclic aromatic hydrocarbon 1-nitropyrene (1-NP) is an environmental pollutant, a potent bacterial and mammalian mutagen, and a carcinogen. The…”
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Separation and detection of 2-aminoanthracene and its metabolites by high-performance liquid chromatography by Shaikh, B, Hallmark, M R, Hallmark, R K, Manning, W B, Pinnock, A, Kawalek, J C

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Reaction of p-quinones with thioamides by Horak, V, Manning, W. B

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Simple synthesis of 1-, 2-, 3-, and 4-hydroxydibenz[a,j]anthracenes and 2-, 3-, and 4-hydroxydibenz[a,h]anthracenes by Muschik, Gary M, Kelly, T. P, Manning, W. B

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A new homogeneous enzyme immunoassay using recombinant enzyme fragments by Khanna, P L, Dworschack, R T, Manning, W B, Harris, J D

“…Homogeneous enzyme immunoassays have played a major role in the development of simple and easy to use diagnostic tests for clinical laboratory instrumentation…”
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Skin carcinogenesis tests in mice of derivatives of 7,12-dimethylbenz[a]anthracene substituted in the 'A' ring by Lijinsky, W, Manning, W B, Andrews, A W

“…Seven derivatives of 7,12-dimethylbenz[a]anthracene (DMBA) having substituents in the 'A' ring have been tested for carcinogenic activity by chronic…”
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