Search Results - "Manning, Sean"
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The role of gut hormone peptide YY in energy and glucose homeostasis: twelve years on
Published in Annual review of physiology (01-01-2014)“…Although the role of peptide YY (PYY) as a regulator of energy homeostasis was first highlighted only in 2002, our understanding of the physiological role of…”
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Metabolic phenotype of skeletal muscle in early critical illness
Published in Thorax (01-10-2018)“…To characterise the sketetal muscle metabolic phenotype during early critical illness. Vastus lateralis muscle biopsies and serum samples (days 1 and 7) were…”
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Neuron cilia restrain glial KCC-3 to a microdomain to regulate multisensory processing
Published in Cell reports (Cambridge) (26-03-2024)“…Glia interact with multiple neurons, but it is unclear whether their interactions with each neuron are different. Our interrogation at single-cell resolution…”
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GLP-1: a mediator of the beneficial metabolic effects of bariatric surgery?
Published in Physiology (Bethesda, Md.) (01-01-2015)“…There has been increasing interest in the role that gut hormones may play in contributing to the physiological changes produced by certain bariatric…”
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Pharmacotherapy for obesity: novel agents and paradigms
Published in Therapeutic Advances in Chronic Disease (01-05-2014)“…Public health initiatives focused on obesity prevention and lifestyle intervention programmes for patients with obesity have struggled to contain the obesity…”
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Preliminary Results in Innovative Solutions for Soil Carbon Estimation: Integrating Remote Sensing, Machine Learning, and Proximal Sensing Spectroscopy
Published in Remote sensing (Basel, Switzerland) (01-12-2023)“…This paper explores the application and advantages of remote sensing, machine learning, and mid-infrared spectroscopy (MIR) as a popular proximal sensing…”
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Latent autoimmune diabetes in adults presenting as diabetes "recurrence" after bariatric surgery: a case report
Published in Diabetes care (01-08-2013)Get full text
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Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery
Published in PloS one (07-08-2013)“…The prevalence of severe obesity, defined as body mass index (BMI) ≥ 35.0 kg/m(2), is rising rapidly. Given the disproportionately high health burden and…”
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Feasibility and Impact of a Combined Supervised Exercise and Nutritional-Behavioral Intervention following Bariatric Surgery: A Pilot Study
Published in Journal of Obesity (01-01-2015)“…Background. Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the…”
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News of the Deluge
Published in Review (Americas Society) (03-07-2023)Get full text
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Roux-en-Y gastric bypass: effects on feeding behavior and underlying mechanisms
Published in The Journal of clinical investigation (01-03-2015)“…Bariatric surgery is the most effective treatment for severe obesity, producing marked sustained weight loss with associated reduced morbidity and mortality…”
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Too Many for an Embassy, too Few for an Army: On the Origin and Scope of a Tigranic Dictum
Published in Zeitschrift für Papyrologie und Epigraphik (01-01-2019)Get full text
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A link between FTO, ghrelin, and impaired brain food-cue responsivity
Published in The Journal of clinical investigation (01-08-2013)“…Polymorphisms in the fat mass and obesity-associated gene (FTO) are associated with human obesity and obesity-prone behaviors, including increased food intake…”
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Ternary tellurite glasses for the fabrication of nonlinear optical fibres
Published in Optical materials express (01-02-2012)“…We investigated the suitability of three ternary tellurite glass families for use as optical fibre materials. Systematically varied compositions were produced…”
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Early postoperative weight loss predicts maximal weight loss after sleeve gastrectomy and Roux-en-Y gastric bypass
Published in Surgical endoscopy (01-06-2015)“…Background Previous studies show that ‘poor responders’ to Roux-en-Y gastric bypass (RYGBP) may be identified on the basis of early postoperative weight loss…”
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Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease
Published in Biochemical Society transactions (01-08-2012)“…The quality control of protein homoeostasis deteriorates with aging, causing the accumulation of misfolded proteins and neurodegeneration. Thus, in AD…”
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The Diabetes Drug Liraglutide Ameliorates Aberrant Insulin Receptor Localisation and Signalling in Parallel with Decreasing Both Amyloid-β Plaque and Glial Pathology in a Mouse Model of Alzheimer’s Disease
Published in Neuromolecular medicine (01-03-2013)“…Alzheimer’s disease (AD) has been shown to involve desensitised insulin receptor (IR) signalling. Liraglutide, a novel glucagon-like peptide 1 (GLP-1) analogue…”
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Dynamic expression of smRNA from fecal exosome in disease progression of an inflammatory bowel disorder mouse model
Published in ExRNA (01-07-2021)Get full text
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Enteroendocrine MC4R and Energy Balance: Linking the Long and the Short of It
Published in Cell metabolism (02-12-2014)“…Central MC4R pathways are well established as integrators of peripheral signals in the control of energy balance. In this issue, Panaro et al. (2014) identify…”
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