Search Results - "Manning, J.M"

Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase by BHATIA, M. B, FUTAKI, S, UENO, H, MANNING, J. M, RINGE, D, YOSHIMURA, T, SODA, K

“…D-Amino acid transaminase (EC 2.6.1.21), from Bacillus sp. YM-1, a thermostable enzyme with pyridoxal 5'-phosphate as coenzyme and a target for the design of…”
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Measurement of Residue Curve Maps and Heterogeneous Kinetics in Methyl Acetate Synthesis by Song, Wei, Venimadhavan, Ganesh, Manning, Jason M, Malone, Michael F, Doherty, Michael F

“…Kinetically controlled reactive distillation is a bridge between the two limiting cases of nonreactive and equilibrium reactive distillation. In this paper, we…”
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Seasonal changes in gonadotropin-releasing hormone secretion in the ewe: alteration in response to the negative feedback action of estradiol by Karsch, F.J, Dahl, G.E, Evans, N.P, Manning, J.M, Mayfield, K.P, Moenter, S.M, Foster, D.L

“…Two experiments were performed to test the hypothesis that there is a seasonal change in the negative feedback effect of estradiol on episodic secretion of…”
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Hongoquercins A and B, new sesquiterpenoid antibiotics: isolation, structure elucidation, and antibacterial activity by Roll, D M, Manning, J K, Carter, G T

“…Two new sesquiterpenoid antibiotics, hongoquercins A and B, were isolated from the extracts of an unidentified fungus. The structures of both metabolites were…”
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Interaction of gamma-glutamyl transpeptidase with acivicin by Stole, E, Smith, T K, Manning, J M, Meister, A

“…Inactivation of gamma-glutamyl transpeptidase by acivicin (L-(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazole acetic acid) is rapid, thought to be…”
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Examples of chemical modification and recombinant DNA approaches with hemoglobin by Manning, J.M.

“…Les dérivés d'hémoglobine sont obtenus par traitement de l'hémoglobine avec un produit possédant les propriétés nécessaires à l'obtention d'un substitut du…”
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Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression by Liu, L. (Kyoto Univ. (Japan)), Yoshimura, T, Endo, K, Kishimoto, K, Fuchikami, Y, Manning, J.M, Esaki, N, Soda, K

“…D-Glutamate, an indispensable component of peptidoglycane of bacteria, is provided by glutamate racemase in E. coli cells. Compensation for D-glutamate…”
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Human acylpeptide hydrolase. Studies on its thiol groups and mechanism of action by SCALONI, A, BARRA, D, JONES, W. M, MANNING, J. M

“…The presence of a cysteine residue(s) near the active site of acylpeptide hydrolase was suggested by inactivation of the enzyme with sulfhydryl-modifying…”
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Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme by SCALONI, A, JONES, W. M, BARRA, D, POSPISCHIL, M, SASSA, S, POPOWICZ, A, MANNING, L. R, SCHNEEWIND, O, MANNING, J. M

“…Acylpeptide hydrolase may be involved in N-terminal deacetylation of nascent polypeptide chains and of bioactive peptides. The activity of this enzyme from…”
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Recombinant Human Sickle Hemoglobin Expressed in Yeast by MARTIN DE LLANO, J. J, SCHNEEWIND, O, STETLER, G, MANNING, J. M

“…Sickle hemoglobin has been expressed in the yeast Saccharomyces cerevisiae after site-directed mutagenesis of a plasmid containing normal human α- and β-globin…”
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Solubility of sickle hemoglobin measured by a kinetic micromethod by Liao, D., Martin de Llano, J.J., Himanen, J.P., Manning, J.M., Ferrone, F.A.

“…We have developed a photolytic method to determine the concentration of reactive hemes in a solution in the presence of a trace amount of CO. By measurement of…”
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Examples of chemical modification and recombinant DNA approaches with hemoglobin by MANNING, J. M

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The Sports Medicine Bible: Prevent, Detect, and Treat Your Sports Injuries Through the Latest Medical Techniques by Manning, J.M

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Determination of free D-amino acids with a bacterial transaminase: their depletion leads to inhibition of bacterial growth by Jones, W M, Ringe, D, Soda, K, Manning, J M

“…A general procedure is described to determine the common free D-amino acids except D-proline in mixtures that also contain L-amino acids. The system employs…”
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Role reversal for substrates and inhibitors. Slow inactivation of D-amino acid transaminase by its normal substrates and protection by inhibitors by Bhatia, M.B., Martinez del Pozo, A., Ringe, D., Yoshimura, T., Soda, K., Manning, J.M.

“…D-Amino acid transaminase, which catalyzes the synthesis of D-alanine and D-glutamate for the bacterial cell wall, is a candidate for the design of specific…”
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Amadori rearrangement of glyceraldehyde-hemoglobin Schiff base adducts. A new procedure for the determination of ketoamine adducts in proteins by Acharya, A S, Manning, J M

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Labeling of hemoglobin with pyridoxal phosphate by Benesch, R, Benesch, R E, Kwong, S, Acharya, A S, Manning, J M

“…The reaction of pyridoxal 5'-phosphate (PLP) with deoxyhemoglobin is confined to 2 residues in the beta chains, i.e. the alpha-amino group of valine 1 and the…”
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Different modes of action of inhibitors of bacterial D-amino acid transaminase. A target enzyme for the design of new antibacterial agents by Soper, T S, Manning, J M

“…D-Amino acid transaminase from Bacillus sphaericus shows a deuterium kinetic isotope effect (VH/VD) between 2 and 3 in the transamination of alpha-protio- or…”
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Reactivity of the amino groups of carbonmonoxyhemoglobin S with glyceraldehyde by Acharya, A S, Manning, J M

“…The inhibition of erythrocyte sickling in vitro by glyceraldehyde has been shown previously to result from a reduced gelation of deoxyhemoglobin S…”
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Oxygen-linked binding sites for inorganic anions to hemoglobin by Nigen, A M, Manning, J M, Alben, J O

“…A hemoglobin hybrid (alpha 2c beta 2 Prov) in which the alpha chains have NH2-terminal residues that have been blocked specifically by carbamylation and beta…”
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