Search Results - "Manning, Alyssa J"

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  1. 1

    Tbx16 and Msgn1 are required to establish directional cell migration of zebrafish mesodermal progenitors by Manning, Alyssa J., Kimelman, David

    Published in Developmental biology (15-10-2015)
    “…The epithelial to mesenchymal transition (EMT) is an essential process that occurs repeatedly during embryogenesis whereby stably adherent cells convert to an…”
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    Journal Article
  2. 2

    High content, high-throughput screening for small molecule inducers of NF-κB translocation by Njikan, Samuel, Manning, Alyssa J, Ovechkina, Yulia, Awasthi, Divya, Parish, Tanya

    Published in PloS one (28-06-2018)
    “…NF-κB is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the optimization…”
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    Journal Article
  3. 3

    Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis by Bosch, Dustin E., Kimple, Adam J., Manning, Alyssa J., Muller, Robin E., Willard, Francis S., Machius, Mischa, Rogers, Stephen L., Siderovski, David P.

    Published in Structure (London) (08-01-2013)
    “…G protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention. Here, we…”
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    Journal Article
  4. 4

    Regulation of epithelial morphogenesis by the G protein-coupled receptor mist and its ligand fog by Manning, Alyssa J, Peters, Kimberly A, Peifer, Mark, Rogers, Stephen L

    Published in Science signaling (12-11-2013)
    “…Epithelial morphogenesis is essential for shaping organs and tissues and for establishment of the three embryonic germ layers during gastrulation. Studies of…”
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    Journal Article
  5. 5

    The Fog signaling pathway: Insights into signaling in morphogenesis by Manning, Alyssa J., Rogers, Stephen L.

    Published in Developmental biology (01-10-2014)
    “…Epithelia form the building blocks of many tissue and organ types. Epithelial cells often form a contiguous 2-dimensional sheet that is held together by strong…”
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    Journal Article
  6. 6

    A high content microscopy assay to determine drug activity against intracellular Mycobacterium tuberculosis by Manning, Alyssa J., Ovechkina, Yulia, McGillivray, Amanda, Flint, Lindsay, Roberts, David M., Parish, Tanya

    Published in Methods (San Diego, Calif.) (15-08-2017)
    “…•New drugs to treat tuberculosis and relevant high-throughput screens are needed.•Macrophages infected with Mtb were treated with compounds in 384-well…”
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    Journal Article
  7. 7

    Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm by Bouldin, Cortney M, Manning, Alyssa J, Peng, Yu-Hsuan, Farr, 3rd, Gist H, Hung, King L, Dong, Alice, Kimelman, David

    Published in Development (Cambridge) (15-07-2015)
    “…Anterior to posterior growth of the vertebrate body is fueled by a posteriorly located population of bipotential neuro-mesodermal progenitor cells. These…”
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    Journal Article
  8. 8

    High content, high-throughput screening for small molecule inducers of NF-[kappa]B translocation by Njikan, Samuel, Manning, Alyssa J, Ovechkina, Yulia, Awasthi, Divya, Parish, Tanya

    Published in PloS one (28-06-2018)
    “…NF-[kappa]B is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the…”
    Get full text
    Journal Article
  9. 9

    Structural Determinants of RGS‐RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis by Bosch, Dustin E, Kimple, Adam J, Manning, Alyssa J, Muller, Robin E, Willard, Francis S, Machius, Mischa, Rogers, Stephen L, Siderovski, David P

    Published in The FASEB journal (01-04-2013)
    “…Abstract only G‐protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention…”
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    Journal Article