Search Results - "Manning, Alyssa J"
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Tbx16 and Msgn1 are required to establish directional cell migration of zebrafish mesodermal progenitors
Published in Developmental biology (15-10-2015)“…The epithelial to mesenchymal transition (EMT) is an essential process that occurs repeatedly during embryogenesis whereby stably adherent cells convert to an…”
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High content, high-throughput screening for small molecule inducers of NF-κB translocation
Published in PloS one (28-06-2018)“…NF-κB is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the optimization…”
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Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis
Published in Structure (London) (08-01-2013)“…G protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention. Here, we…”
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Regulation of epithelial morphogenesis by the G protein-coupled receptor mist and its ligand fog
Published in Science signaling (12-11-2013)“…Epithelial morphogenesis is essential for shaping organs and tissues and for establishment of the three embryonic germ layers during gastrulation. Studies of…”
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5
The Fog signaling pathway: Insights into signaling in morphogenesis
Published in Developmental biology (01-10-2014)“…Epithelia form the building blocks of many tissue and organ types. Epithelial cells often form a contiguous 2-dimensional sheet that is held together by strong…”
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6
A high content microscopy assay to determine drug activity against intracellular Mycobacterium tuberculosis
Published in Methods (San Diego, Calif.) (15-08-2017)“…•New drugs to treat tuberculosis and relevant high-throughput screens are needed.•Macrophages infected with Mtb were treated with compounds in 384-well…”
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Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm
Published in Development (Cambridge) (15-07-2015)“…Anterior to posterior growth of the vertebrate body is fueled by a posteriorly located population of bipotential neuro-mesodermal progenitor cells. These…”
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High content, high-throughput screening for small molecule inducers of NF-[kappa]B translocation
Published in PloS one (28-06-2018)“…NF-[kappa]B is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the…”
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Journal Article -
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Structural Determinants of RGS‐RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis
Published in The FASEB journal (01-04-2013)“…Abstract only G‐protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention…”
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