Search Results - "Manni, Jeffrey"
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1
Transforming a Mid-infrared Laser Profile from Gaussian to a Top-Hat with a Diffractive Optical Element for Mass Spectrometry Imaging
Published in Journal of the American Society for Mass Spectrometry (04-01-2023)“…Many mass spectrometry imaging (MSI) applications such as infrared matrix-assisted electrospray ionization (IR-MALDESI) employ an infrared (IR) laser with a…”
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2
Characterization of a novel miniaturized burst-mode infrared laser system for IR-MALDESI mass spectrometry imaging
Published in Analytical and bioanalytical chemistry (01-03-2018)“…Laser systems are widely used in mass spectrometry as sample probes and ionization sources. Mid-infrared lasers are particularly suitable for analysis of high…”
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3
Improved spatial resolution of infrared matrix‐assisted laser desorption electrospray ionization mass spectrometry imaging using a reflective objective
Published in Rapid communications in mass spectrometry (15-12-2022)“…Rationale The level of visual detail of a mass spectrometry image is dependent on the spatial resolution with which it is acquired, which is largely determined…”
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4
Versatile method for achieving 1% speckle contrast in large-venue laser projection displays using a stationary multimode optical fiber
Published in Optics express (07-05-2012)“…We propose a method based on quantitative theoretical analysis for achieving speckle contrast of 1% or less in images created by a full-frame laser projection…”
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5
Quasi‐continuous infrared matrix‐assisted laser desorption electrospray ionization source coupled to a quadrupole time‐of‐flight mass spectrometer for direct analysis from well plates
Published in Journal of mass spectrometry. (01-01-2023)“…High‐throughput screening (HTS) is a technique mostly used by pharmaceutical companies to rapidly screen multiple libraries of compounds to find drug hits with…”
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6
Obtaining 20 μm Spatial Resolution with a 2940 nm Laser by IR-MALDESI Mass Spectrometry Imaging
Published in Journal of the American Society for Mass Spectrometry (08-11-2024)“…High spatial resolution is a key parameter in mass spectrometry imaging (MSI), enabling a greater understanding of system biology and cellular processes. Using…”
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IR-MALDESI Mass Spectrometry Imaging at 50 Micron Spatial Resolution
Published in Journal of the American Society for Mass Spectrometry (01-10-2017)“…High spatial resolution in mass spectrometry imaging (MSI) is crucial to understanding the biology dictated by molecular distributions in complex tissue…”
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8
Near-infrared Photoinactivation of Bacteria and Fungi at Physiologic Temperatures
Published in Photochemistry and photobiology (01-11-2009)“…We examined a laser system (870 and 930 nm), employing wavelengths that have exhibited cellular photodamage properties in optical traps. In vitro, with 1.5 cm…”
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9
Amplification of microchip oscillator emission using a diode-pumped wedged-slab amplifier
Published in Optics communications (01-08-2005)“…A master-oscillator power-amplifier (MOPA) system combines a 1064-nm microchip laser oscillator with a new diode-side-pumped Nd:YVO 4 zig-zag slab amplifier…”
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10
100-W Q -switched Cryogenically Cooled Yb:YAG Laser
Published in IEEE journal of quantum electronics (01-01-2010)“…This work describes a cryogenic, electro-optically Q -switched Yb:YAG laser that generates 114-W average TEM 00 power with 47% optical-to-optical efficiency…”
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11
High-gain (43 dB), high-power (40 W), highly efficient multipass amplifier at 995 nm in Yb:LiYF4
Published in Optics communications (15-06-2018)“…A simple implementation of a multipass amplifier along with the use of a cryogenic Yb:LiYF4 (YLF) gain medium has enabled the demonstration of a bulk amplifier…”
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12
Quasi-Continuous IR-MALDESI Source Coupled to a Q-TOF Mass Spectrometer for Direct Analysis from Well Plates
Published in Journal of mass spectrometry. (01-01-2023)“…High-throughput screening (HTS) is a technique mostly used by pharmaceutical companies to rapidly screen multiple libraries of compounds to find drug hits with…”
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13
A quasi-continuous-wave deep ultraviolet laser source
Published in IEEE journal of quantum electronics (01-09-2003)“…We have developed a quasi-CW, deep ultraviolet source producing >250 mW of 205-nm radiation. The source consists of a 100-MHz, mode-locked, 15-W, 1047-nm…”
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14
Next-Generation Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Source for Mass Spectrometry Imaging and High-Throughput Screening
Published in Journal of the American Society for Mass Spectrometry (02-11-2022)“…Infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) is a hybrid, ambient ionization source that combines the advantages of…”
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15
Spectroscopic and laser characteristics of Er,Cr:YSGG
Published in IEEE journal of quantum electronics (01-06-1988)“…The spectroscopic and laser properties of crystal Er,Cr:YSGG are discussed and it is shown that excitation is efficiently transferred from chromium to erbium…”
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