Search Results - "Mannelli, M."

Prognostic factors in stage III–IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study by Libé, R., Borget, I., Ronchi, C.L., Zaggia, B., Kroiss, M., Kerkhofs, T., Bertherat, J., Volante, M., Quinkler, M., Chabre, O., Bala, M., Tabarin, A., Beuschlein, F., Vezzosi, D., Deutschbein, T., Borson-Chazot, F., Hermsen, I., Stell, A., Fottner, C., Leboulleux, S., Hahner, S., Mannelli, M., Berruti, A., Haak, H., Terzolo, M., Fassnacht, M., Baudin, E.

“…The clinical course of advanced adrenocortical carcinoma (ACC) is heterogeneous. Our study aimed primarily to refine and make headway in the prognostic…”
Get full text

Management and outcome of metastatic pheochromocytomas/paragangliomas: an overview by De Filpo, G., Maggi, M., Mannelli, M., Canu, L.

“…Background Metastatic pheochromocytomas and paragangliomas (PPGLs) occur in about 5–26% of cases and are characterized by a heterogeneous prognosis. Metastases…”
Get full text

Management and outcome of metastatic pheochromocytomas/paragangliomas: a monocentric experience by De Filpo, G., Cantini, G., Rastrelli, G., Vannini, G., Ercolino, T., Luconi, M., Mannelli, M., Maggi, M., Canu, L.

“…Background Pheochromocytoma (PHEO) and paraganglioma (PGL) are rare neuroendocrine tumors releasing catecholamines. Metastatic pheochromocytomas/paragangliomas…”
Get full text

Carbonic anhydrases III and IX are new players in the crosstalk between adrenocortical carcinoma and its altered adipose microenvironment by Fei, L., Cantini, G., Nocentini, A., Nardini, P., Catarinicchia, S., Canu, L., Ercolino, T., Quartararo, G., Nesi, G., Gacci, M., Maggi, M., Hantel, C., Mannelli, M., Supuran, C. T., Luconi, M.

“…Purpose Adrenocortical carcinoma (ACC), a rare malignancy of the adrenocortex, is characterized by a crosstalk between the adipose microenvironment and tumor…”
Get full text

The cytoskeleton actin binding protein filamin A impairs both IGF2 mitogenic effects and the efficacy of IGF1R inhibitors in adrenocortical cancer cells by Catalano, R., Giardino, E., Treppiedi, D., Mangili, F., Morelli, V., Elli, F.M., Serban, A.L., Luconi, M., Mannelli, M., Spada, A., Arosio, M., Mantovani, G., Peverelli, E.

“…Adrenocortical carcinomas (ACCs) overexpress insulin-like growth factor 2 (IGF2), that drives a proliferative autocrine loop by binding to IGF1R and IR, but…”
Get full text

Adrenocortical carcinoma: the dawn of a new era of genomic and molecular biology analysis by Armignacco, R., Cantini, G., Canu, L., Poli, G., Ercolino, T., Mannelli, M., Luconi, M.

“…Over the last decade, the development of novel and high penetrance genomic approaches to analyze biological samples has provided very new insights in the…”
Get full text

Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma by Eisenhofer, Graeme, Pacak, Karel, Huynh, Thanh-Truc, Qin, Nan, Bratslavsky, Gennady, Linehan, W Marston, Mannelli, Massimo, Friberg, Peter, Grebe, Stefan K, Timmers, Henri J, Bornstein, Stefan R, Lenders, Jacques W M

“…Phaeochromocytomas and paragangliomas (PPGLs) are highly heterogeneous tumours with variable catecholamine biochemical phenotypes and diverse hereditary…”
Get full text

Clinical impact of the new SIAPEC-IAP classification on the indeterminate category of thyroid nodules by Sparano, C., Parenti, G., Cilotti, A., Bencini, L., Calistri, M., Mannucci, E., Biagini, C., Vezzosi, V., Mannelli, M., Forti, G., Petrone, L.

“…Background The increasing frequency in the diagnosis of thyroid nodules has raised a growing interest in the search for new diagnostic tools to better select…”
Get full text

The IGF2 methylation score for adrenocortical cancer: an ENSAT validation study by Creemers, S G, Feelders, R A, Valdes, N, Ronchi, C L, Volante, M, van Hemel, B M, Luconi, M, Ettaieb, M H T, Mannelli, M, Chiara, M D, Fassnacht, M, Papotti, M, Kerstens, M N, Nesi, G, Haak, H R, van Kemenade, F J, Hofland, L J

“…Adrenocortical carcinoma (ACC) is diagnosed using the histopathological Weiss score (WS), but remains clinically elusive unless it has metastasized or grows…”
Get full text

A unique neuroendocrine cell model derived from the human foetal neural crest by Rapizzi, E., Benvenuti, S., Deledda, C., Martinelli, S., Sarchielli, E., Fibbi, B., Luciani, P., Mazzanti, B., Pantaleo, M., Marroncini, G., Vannelli, G. B., Maggi, M., Mannelli, M., Luconi, M., Peri, A.

“…Purpose Nowadays, no human neuroendocrine cell models derived from the neural crest are available. In this study, we present non-transformed long-term primary…”
Get full text

Guidelines for diagnosis and therapy of MEN type 1 and type 2 by Brandi, M L, Gagel, R F, Angeli, A, Bilezikian, J P, Beck-Peccoz, P, Bordi, C, Conte-Devolx, B, Falchetti, A, Gheri, R G, Libroia, A, Lips, C J, Lombardi, G, Mannelli, M, Pacini, F, Ponder, B A, Raue, F, Skogseid, B, Tamburrano, G, Thakker, R V, Thompson, N W, Tomassetti, P, Tonelli, F, Wells, Jr, S A, Marx, S J

“…This is a consensus statement from an international group, mostly of clinical endocrinologists. MEN1 and MEN2 are hereditary cancer syndromes. The commonest…”
Get full text

Distinct gene expression profiles in norepinephrine- and epinephrine-producing hereditary and sporadic pheochromocytomas: activation of hypoxia-driven angiogenic pathways in von Hippel–Lindau syndrome by Eisenhofer, G, Huynh, T-T, Pacak, K, Brouwers, F M, Walther, M M, Linehan, W M, Munson, P J, Mannelli, M, Goldstein, D S, Elkahloun, A G

“…Pheochromocytomas in von Hippel–Lindau (VHL) syndrome produce exclusively norepinephrine, whereas those in multiple endocrine neoplasia type 2 (MEN 2) produce…”
Get full text

On the timing performance of thin planar silicon sensors by Akchurin, N., Ciriolo, V., Currás, E., Damgov, J., Fernández, M., Gallrapp, C., Gray, L., Junkes, A., Mannelli, M., Martin Kwok, K.H., Meridiani, P., Moll, M., Nourbakhsh, S., Pigazzini, S., Scharf, C., Silva, P., Steinbrueck, G., de Fatis, T. Tabarelli, Vila, I.

“…We report on the signal timing capabilities of thin silicon sensors when traversed by multiple simultaneous minimum ionizing particles (MIP). Three different…”
Get full text

Pheochromocytoma in Italy : a multicentric retrospective study by MANNELLI, M, IANNI, L, CILOTTI, A, CONTI, A

“…To conduct an epidemiological study on pheochromocytoma in Italy. Data on 284 patients with pheochromocytoma observed between 1978 and 1997 were collected from…”
Get full text

Genetic screening for pheochromocytoma: should SDHC gene analysis be included? by Mannelli, M, Ercolino, T, Giachè, V, Simi, L, Cirami, C, Parenti, G

“…PGL3 syndrome is caused by mutations in the SDHC gene. At present, only a few families affected by SDHC mutations have been reported in the literature and in…”
Get full text

Progress in primary aldosteronism: present challenges and perspectives by Gomez-Sanchez, C E, Rossi, G P, Fallo, F, Mannelli, M

“…Primary Aldosteronism (PA) is a disorder of the adrenal zona glomerulosa (ZG) in which aldosterone secretion is increased and is relatively autonomous of…”
Get more information

Biochemistry, genetics and therapy of malignant pheochromocytomas by Mannelli, M

Get full text

Immunohistochemical expression of stem cell markers in pheochromocytomas/paragangliomas is associated with SDHx mutations by Oudijk, L, Neuhofer, C M, Lichtenauer, U D, Papathomas, T G, Korpershoek, E, Stoop, H, Oosterhuis, J W, Smid, M, Restuccia, D F, Robledo, M, de Cubas, A A, Mannelli, M, Gimenez-Roqueplo, A P, Dinjens, W N M, Beuschlein, F, de Krijger, R R

“…ObjectivePheochromocytomas (PCCs) are neuroendocrine tumors that occur in the adrenal medulla, whereas paragangliomas (PGLs) arise from paraganglia in the…”
Get full text

Mitochondrial function and content in pheochromocytoma/paraganglioma of succinate dehydrogenase mutation carriers by Rapizzi, E, Ercolino, T, Canu, L, Giaché, V, Francalanci, M, Pratesi, C, Valeri, A, Mannelli, M

“…To date, the consequences of succinate dehydrogenase (SDH) impairment on overall mitochondrial functions are still obscure. In this study, we evaluated SDH…”
Get full text

[OP.3A.06] LONG TERM FOLLOW-UP IN PATIENTS OPERATED ON A PHEOCHROMOCYTOMA OR A PARAGANGLIOMA: COMPILATION OF THE ENS@T DATABASE by Amar, L, Deutschbein, T, Piscaer, I, Brugger, C, Canu, L, Bertherat, J, Lepoutre, C, Dekkers, O, Stell, A, Gimenez-roqueplo, A, Fassnacht, M, Robledo, M, Mannelli, M, Lenders, J, Timmers, H, Beuschlein, F, Curras-freixes, M, Plouin, P.-F, Steichen, O

“…OBJECTIVE:Following resection of the primary tumor, patients with pheochromocytoma or paragangliomas (PPGL) are at risk of tumor persistence or tumor…”
Get full text