Search Results - "Mannella, Iole"

Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis by Wróbel, Tomasz M, Sharma, Katyayani, Mannella, Iole, Oliaro-Bosso, Simonetta, Nieckarz, Patrycja, Du Toit, Therina, Voegel, Clarissa Daniela, Rojas Velazquez, Maria Natalia, Yakubu, Jibira, Matveeva, Anna, Therkelsen, Søren, Jørgensen, Flemming Steen, Pandey, Amit V, Pippione, Agnese C, Lolli, Marco L, Boschi, Donatella, Björkling, Fredrik

“…This study reports on the synthesis and evaluation of novel compounds replacing the nitrogen-containing heterocyclic ring on the chemical backbone structure of…”
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Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer by Pippione, Agnese Chiara, Kovachka, Sandra, Vigato, Chiara, Bertarini, Laura, Mannella, Iole, Sainas, Stefano, Rolando, Barbara, Denasio, Enrica, Piercy-Mycock, Helen, Romalho, Linda, Salladini, Edoardo, Adinolfi, Salvatore, Zonari, Daniele, Peraldo-Neia, Caterina, Chiorino, Giovanna, Passoni, Alice, Mirza, Osman Asghar, Frydenvang, Karla, Pors, Klaus, Lolli, Marco Lucio, Spyrakis, Francesca, Oliaro-Bosso, Simonetta, Boschi, Donatella

“…AKR1C3 is an enzyme that is overexpressed in several types of radiotherapy- and chemotherapy-resistant cancers. Despite AKR1C3 is a validated target for drug…”
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