Search Results - "Mannebach, Stefanie"
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1
Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels
Published in Cellular physiology and biochemistry (10-11-2020)Get full text
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2
Alternative Splicing of a Protein Domain Indispensable for Function of Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels
Published in The Journal of biological chemistry (26-10-2012)“…TRPM3 channels form ionotropic steroid receptors in the plasma membrane of pancreatic β and dorsal root ganglion cells and link steroid hormone signaling to…”
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Excision of Trpv6 Gene Leads to Severe Defects in Epididymal Ca2+ Absorption and Male Fertility Much Like Single D541A Pore Mutation
Published in The Journal of biological chemistry (25-05-2012)“…Replacement of aspartate residue 541 by alanine (D541A) in the pore of TRPV6 channels in mice disrupts Ca2+ absorption by the epididymal epithelium, resulting…”
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Transient Receptor Potential Melastatin 1 (TRPM1) Is an Ion-conducting Plasma Membrane Channel Inhibited by Zinc Ions
Published in The Journal of biological chemistry (08-04-2011)“…TRPM1 is the founding member of the melastatin subgroup of transient receptor potential (TRP) proteins, but it has not yet been firmly established that TRPM1…”
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Signal Transduction of Pregnenolone Sulfate in Insulinoma Cells
Published in The Journal of biological chemistry (01-03-2011)“…The neurosteroid pregnenolone sulfate acts on the nervous system by modifying neurotransmission and receptor functions, thus influencing synaptic strength,…”
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Cavβ3 Contributes to the Maintenance of the Blood-Brain Barrier and Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2024)“…Tight control of cytoplasmic Ca concentration in endothelial cells is essential for the regulation of endothelial barrier function. Here, we investigated the…”
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Promiscuous G-Protein-Coupled Receptor Inhibition of Transient Receptor Potential Melastatin 3 Ion Channels by Gβγ Subunits
Published in The Journal of neuroscience (02-10-2019)“…Transient receptor potential melastatin 3 (TRPM3) is a nonselective cation channel that is inhibited by Gβγ subunits liberated following activation of Gα…”
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Signal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factors
Published in The Journal of biological chemistry (25-03-2011)“…The neurosteroid pregnenolone sulfate acts on the nervous system by modifying neurotransmission and receptor functions, thus influencing synaptic strength,…”
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Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells
Published in Nature cell biology (01-12-2008)“…In an unanticipated cross-talk between the steroid and insulin endocrine systems, the neuroactive steroid pregnenolone sulphate is found to activate the TRPM3…”
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10
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
Published in European heart journal (01-09-2015)“…Pathological cardiac hypertrophy is a major predictor for the development of cardiac diseases. It is associated with chronic neurohumoral stimulation and with…”
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11
Cytotoxic granule endocytosis depends on the Flower protein
Published in The Journal of cell biology (05-02-2018)“…Cytotoxic T lymphocytes (CTLs) kill target cells by the regulated release of cytotoxic substances from granules at the immunological synapse. To kill multiple…”
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12
TRPM4-mediated control of FcεRI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells
Published in Scientific reports (14-09-2016)“…TRPM4 proteins form Ca 2+ -activated non selective cation (CAN) channels that affect transmembrane Ca 2+ -influx by determining the membrane potential. Tight…”
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13
TRPM4-mediated control of FcεRI-evoked Ca(2+) elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells
Published in Scientific reports (14-09-2016)“…TRPM4 proteins form Ca(2+)-activated non selective cation (CAN) channels that affect transmembrane Ca(2+)-influx by determining the membrane potential. Tight…”
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14
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
Published in The Journal of clinical investigation (01-04-2024)“…Regulated exocytosis is initiated by increased Ca2+ concentrations in close spatial proximity to secretory granules, which is effectively prevented when the…”
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15
Calcium-dependence of cytotoxic granule endocytosis depends on the Flower protein
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Cytotoxic T lymphocytes (CTLs) kill their targets by secreting perforin and granzymes from cytotoxic granules (CGs) at the interface between CTL and…”
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16
Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells
Published in Science advances (22-09-2023)“…Migratory dendritic cells (migDCs) continuously patrol tissues and are activated by injury and inflammation. Extracellular adenosine triphosphate (ATP) is…”
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A background Ca 2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
Published in European heart journal (01-09-2015)Get full text
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18
TRPM4-mediated control of Fc[epsilon]RI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells
Published in Scientific reports (01-09-2016)“…TRPM4 proteins form Ca2+ -activated non selective cation (CAN) channels that affect transmembrane Ca2+ -influx by determining the membrane potential. Tight…”
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19
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic [beta] cells
Published in Nature cell biology (01-12-2008)“…Transient receptor potential (TRP) cation channels are renowned for their ability to sense diverse chemical stimuli. Still, for many members of this large and…”
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Mouse Flower‐like (mFl), a membrane protein involved in endocytosis?
Published in The FASEB journal (01-04-2013)“…Abstract only Recently, a novel membrane protein in Drosophila melanogaster was shown to be localized in presynaptic vesicles. It appears to mediate a Ca…”
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