Search Results - "Mannall, Gareth J."

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  1. 1
    An ultra scale-down approach to study the interaction of fermentation, homogenization, and centrifugation for antibody fragment recovery from rec E. coli

    An ultra scale-down approach to study the interaction of fermentation, homogenization, and centrifugation for antibody fragment recovery from rec E. coli by Li, Qiang, Mannall, Gareth J., Ali, Shaukat, Hoare, Mike

    Published in Biotechnology and bioengineering (01-08-2013)
    “…Escherichia coli is frequently used as a microbial host to express recombinant proteins but it lacks the ability to secrete proteins into medium. One option…”
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  2. 2
    Factors affecting protein refolding yields in a fed-batch and batch-refolding system

    Factors affecting protein refolding yields in a fed-batch and batch-refolding system by Mannall, Gareth J., Titchener-Hooker, Nigel J., Dalby, Paul A.

    Published in Biotechnology and bioengineering (15-08-2007)
    “…The refolding of recombinant protein from inclusion bodies expressed in Escherichia coli can present a process bottleneck. Yields at industrially relevant…”
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  3. 3
    Ultra scale-down of protein refold screening in microwells: Challenges, solutions and application

    Ultra scale-down of protein refold screening in microwells: Challenges, solutions and application by Mannall, Gareth J, Myers, James P, Liddell, John, Titchener-Hooker, Nigel J, Dalby, Paul A

    Published in Biotechnology and bioengineering (01-06-2009)
    “…Steps for the refolding of proteins from solubilized inclusion bodies or misfolded product often represent bottlenecks in process development, where optimal…”
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  4. 4
    A critical assessment of the impact of mixing on dilution refolding

    A critical assessment of the impact of mixing on dilution refolding by Mannall, Gareth J., Titchener-Hooker, Nigel J., Chase, Howard A., Dalby, Paul A.

    Published in Biotechnology and bioengineering (05-04-2006)
    “…Refolding often presents a bottleneck in the generation of recombinant protein expressed as inclusion bodies. Few studies have looked at the effect of physical…”
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  5. 5
    Integrated ultra scale-down and multivariate analysis of flocculation and centrifugation for enhanced primary recovery

    Integrated ultra scale-down and multivariate analysis of flocculation and centrifugation for enhanced primary recovery by Nunes, Sofia L.V., Mannall, Gareth J., Rayat, Andrea C.M.E.

    Published in Food and bioproducts processing (01-05-2023)
    “…A linked ultra scale-down (USD) flocculation and centrifugation system facilitates rapid bioprocess development and evaluation. These techniques allow studies…”
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  6. 6
    Ultra scale-down of protein retold screening in microwells: Challenges, solutions and application

    Ultra scale-down of protein retold screening in microwells: Challenges, solutions and application by Mannall, Gareth J, Myers, James P, Liddell, John, Titchener-Hooker, Nigel J, Dalby, Paul A

    Published in Biotechnology and bioengineering (01-06-2009)
    “…Steps for the refolding of proteins from solubilized inclusion bodies or misfolded product often represent bottlenecks in process development, where optimal…”
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