Search Results - "Mannaioni, G"

Optical mapping of neuronal activity during seizures in zebrafish by Turrini, L., Fornetto, C., Marchetto, G., Müllenbroich, M. C., Tiso, N., Vettori, A., Resta, F., Masi, A., Mannaioni, G., Pavone, F. S., Vanzi, F.

“…Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology…”
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Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy by Resta, F., Micheli, L., Laurino, A., Spinelli, V., Mello, T., Sartiani, L., Di Cesare Mannelli, L., Cerbai, E., Ghelardini, C., Romanelli, M.N., Mannaioni, G., Masi, A.

“…Chemotherapy-Induced Peripheral Neuropathy (CIPN) is the most frequent adverse effect of pharmacological cancer treatments. The occurrence of neuropathy…”
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Harnessing ionic mechanisms to achieve disease modification in neurodegenerative disorders by Masi, A, Narducci, R, Mannaioni, G

“…[Display omitted] Progressive neuronal death is the key pathogenic event leading to clinical symptoms in neurodegenerative disorders (NDDs). Neuroprotective…”
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Acute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder by Iezzi, D., Curti, L., Ranieri, G., Gerace, E., Costa, A., Ilari, A., La Rocca, A., Luceri, C., D’Ambrosio, M., Silvestri, L., Scardigli, M., Mannaioni, G., Masi, A.

“…We previously demonstrated that prenatal exposure to valproic acid (VPA), an environmental model of autism spectrum disorder (ASD), leads to a hyperexcitable…”
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Moderate ethanol drinking is sufficient to alter Ventral Tegmental Area dopamine neurons activity via functional and structural remodeling of GABAergic transmission by Ilari, A., Curti, L., Petrella, M., Cannella, N., La Rocca, A., Ranieri, G., Gerace, E., Iezzi, D., Silvestri, L., Mannaioni, G., Ciccocioppo, R., Masi, A.

“…Earlier studies have shown a major involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons in mediating the rewarding effects of ethanol (EtOH). Much…”
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Equianalgesia, opioid switch and opioid association in different clinical settings: a narrative review by De Iaco, F, Mannaioni, G, Serra, S, Finco, G, Sartori, S, Gandolfo, E, Sansone, P, Marinangeli, F

“…Emergency or postoperative pain often represents an authentic challenge in patients who were already on opioid treatment for chronic pain. Thus, their…”
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PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca(2+)-permeable AMPA receptors by Gerace, E, Masi, A, Resta, F, Felici, R, Landucci, E, Mello, T, Pellegrini-Giampietro, D E, Mannaioni, G, Moroni, F

“…An excessive activation of poly(ADP-ribose) polymerases (PARPs) may trigger a form of neuronal death similar to that occurring in neurodegenerative disorders…”
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MPP + ‐dependent inhibition of I h reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons by Masi, A, Narducci, R, Landucci, E, Moroni, F, Mannaioni, G

“…Background and Purpose 1‐Methyl‐4‐phenylpyridinium ( MPP + ), a potent parkinsonizing agent in primates and rodents, is a blocker of mitochondrial complex I ,…”
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MPP+‐dependent inhibition of Ih reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons by Masi, A, Narducci, R, Landucci, E, Moroni, F, Mannaioni, G

“…Background and Purpose 1‐Methyl‐4‐phenylpyridinium (MPP+), a potent parkinsonizing agent in primates and rodents, is a blocker of mitochondrial complex I,…”
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PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2+-permeable AMPA receptors by Gerace, E., Masi, A., Resta, F., Felici, R., Landucci, E., Mello, T., Pellegrini-Giampietro, D.E., Mannaioni, G., Moroni, F.

“…An excessive activation of poly(ADP-ribose) polymerases (PARPs) may trigger a form of neuronal death similar to that occurring in neurodegenerative disorders…”
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Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges by Attucci, S, Carlà, V, Mannaioni, G, Moroni, F

“…We measured the effects of agonists and antagonists of metabotropic glutamate (mGlu) receptors (types 1 and 5) on NMDA‐induced depolarization of mouse cortical…”
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761 PERIPHERAL AND SPLANCHNIC INDOLE AND OXINDOLE LEVELS IN CIRRHOTIC PATIENTS: A STUDY ON THE PATHOPHYSIOLOGY OF HEPATIC ENCEPHALOPATHY by Ridola, L, Mannaioni, G, Angeloni, S, Merli, M, Carla', V, Salvatori, F, Moroni, F, Riggio, O

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Peripheral and splanchnic indole and oxindole levels in cirrhotic patients: A study on the pathophysiology of hepatic encephalopathy by Ridola, L, Mannaioni, G, Angeloni, S, Merli, M, Carlà, V, Salvatori, F.M, Moroni, F, Riggio, O

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Real-World Patterns and Trends of Idarucizumab Use in an Italian Region: A Probabilistic Record-Linkage Approach in the Period 2015-2020 by Lombardi, N, Crescioli, G, Brilli, V, Antonazzo, I C, Mazzaglia, G, Fumagalli, S, Mannaioni, G, Vannacci, A, Gini, R

“…Introduction: Idarucizumab is a specific reversal agent for dabigatran that was approved in 2015 to restore coagulation. The drug is administered only during…”
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Patterns and trends of idarucizumab use in an Italian region: a probabilistic record-linkage approach in a real-life setting by Lombardi, N, Brilli, V, Crescioli, G, Bettiol, A, Ippazio, C.A, Mazzaglia, G, Fumagalli, S, Mannaioni, G, Vannacci, A, Gini, R

“…Abstract Background Idarucizumab is a specific reversal agent for dabigatran, a direct oral anticoagulant. In 2015, idarucizumab was approved in Europe to…”
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Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations by Mannaioni, Guido, Carlà, Vincenzo, Moroni, Flavio

“…1 Mouse cortical wedge preparations were used in order to study the effects of metabotropic glutamate receptor (mGluR) agonists and antagonists on the…”
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HCN Channels Modulators: The Need for Selectivity by Novella Romanelli, Maria, Sartiani, Laura, Masi, Alessio, Mannaioni, Guido, Manetti, Dina, Mugelli, Alessandro, Cerbai, Elisabetta

“…Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels, the molecular correlate of the hyperpolarization-activated current (If/Ih), are membrane…”
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MPP super(+)-dependent inhibition of I sub(h) reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons by Masi, A, Narducci, R, Landucci, E, Moroni, F, Mannaioni, G

“…Background and Purpose 1-Methyl-4-phenylpyridinium (MPP super(+)), a potent parkinsonizing agent in primates and rodents, is a blocker of mitochondrial complex…”
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Ammonium acetate inhibits ionotropic receptors and differentially affects metabotropic receptors for glutamate by LOMBARDI, G, MANNAIONI, G, LEONARDI, P, CHERICI, G, CARLA, V, MORONI, F

“…The effects of ammonium salts in concentration similar to those found in plasma in course of hepatic encephalopathy (2-4 mM) were studied in brain slices in…”
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A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: Determination of MDPV metabolites by LC–HRMS and discussion of the case by Bertol, Elisabetta, Mari, Francesco, Boscolo Berto, Rafael, Mannaioni, Guido, Vaiano, Fabio, Favretto, Donata

“…Highlights • Two episodes of MDPV intoxication for the same subject are reported. • Symptoms and self-reported manner of use are described. • MDPV and its…”
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