Search Results - "Manna, Raffaele"

The everchanging framework of autoinflammation by Manna, Raffaele, Rigante, Donato

“…The innate immunity works as a defence bullwark that safeguards healthy tissues with the power of detecting infectious agents in the human body: errors in the…”
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Familial Mediterranean Fever: Assessing the Overall Clinical Impact and Formulating Treatment Plans by Manna, Raffaele, Rigante, Donato

“…Recurrent self-limited attacks of fever and short-lived inflammation in the serosal membranes, joints, and skin are the leading features of familial…”
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Current Therapeutic Options for the Main Monogenic Autoinflammatory Diseases and PFAPA Syndrome: Evidence-Based Approach and Proposal of a Practical Guide by Soriano, Alessandra, Soriano, Marco, Espinosa, Gerard, Manna, Raffaele, Emmi, Giacomo, Cantarini, Luca, Hernández-Rodríguez, José

“…Monogenic autoinflammatory diseases are rare conditions caused by genetic abnormalities affecting the innate immunity. Previous therapeutic strategies had been…”
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Rare missense variants in the ALPK1 gene may predispose to periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome by Sangiorgi, Eugenio, Azzarà, Alessia, Molinario, Clelia, Pietrobono, Roberta, Rigante, Donato, Verrecchia, Elena, Sicignano, Ludovico Luca, Genuardi, Maurizio, Gurrieri, Fiorella, Manna, Raffaele

“…PFAPA is an autoinflammatory syndrome characterized by periodic fever, aphthous stomatitis, sterile pharingitis, and adenitis, with an onset usually before the…”
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NLRP12 gene mutations and auto-inflammatory diseases: ever-changing evidence by Del Porto, Flavia, Cifani, Noemi, Proietta, Maria, Verrecchia, Elena, Di Rosa, Roberta, Manna, Raffaele, Chiurazzi, Pietro

“…Abstract Systemic auto-inflammatory diseases (SAID) are a group of rare inherited conditions characterized by a dysregulation of the immune system and…”
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An uplifted destiny for mucopolysaccharidosis type I with heart valve involvement by Manna, Raffaele, Graziani, Francesca, Lillo, Rosa, Verrecchia, Elena, Sicignano, Luca Ludovico, Rigante, Donato

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Clinical hints to diagnosis of attenuated forms of Mucopolysaccharidoses by Rigoldi, Miriam, Verrecchia, Elena, Manna, Raffaele, Mascia, Maria Teresa

“…The mucopolysaccharidoses (MPS) are clinically similar but also heterogeneous in terms of major or minor involvement of different organs/systems, burden of…”
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Early introduction of anakinra improves acute pericarditis and prevents tamponade in Staphylococcal sepsis by Sicignano, Ludovico Luca, Massaro, Maria Grazia, Savino, Marinica, Rigante, Donato, Gerardino, Laura, Manna, Raffaele

“…The clinical response to anakinra observed by this patient concurrently treated with antibiotics indirectly confirms the potentially pathogenic role of IL-1 in…”
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Spider Bite Presenting as Fever, Macrophage Activation Syndrome and a Skin Ulcer by Fedele, Marco, Antonelli, Mariangela, Carbone, Egidio, Di Stefano, Marco, Manna, Raffaele, Addolorato, Giovanni

“…Fever of unknown origin (FUO) refers to a condition of prolonged increased body temperature, without identified causes. The most common cause of FUO worldwide…”
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Diagnostic Criteria for Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome by Cantarini, Luca, Vitale, Antonio, Sicignano, Ludovico Luca, Emmi, Giacomo, Verrecchia, Elena, Patisso, Isabella, Cerrito, Lucia, Fabiani, Claudia, Cevenini, Gabriele, Frediani, Bruno, Galeazzi, Mauro, Rigante, Donato, Manna, Raffaele

“…To identify a set of variables that could discriminate patients with adult-onset periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis…”
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Mesothelioma in Familial Mediterranean Fever With Colchicine Intolerance: A Case Report and Literature Review by Talerico, Rosa, Cardillo, Carmine, De Vito, Francesco, Schinzari, Francesca, Soldato, Manuel, Giustiniani, Maria Cristina, Verrecchia, Elena, Manna, Raffaele

“…A 65-year-old Italian physician affected by Familial Mediterranean fever (FMF) was hospitalized due to progressive abdominal enlargement, which had begun 6…”
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Right Ventricular Hypertrophy, Systolic Function, and Disease Severity in Anderson-Fabry Disease: An Echocardiographic Study by Graziani, Francesca, MD, PhD, Laurito, Marianna, MD, Pieroni, Maurizio, MD, PhD, Pennestrì, Faustino, MD, Lanza, Gaetano Antonio, MD, Coluccia, Valentina, MD, Camporeale, Antonia, MD, Pedicino, Daniela, MD, Verrecchia, Elena, MD, Manna, Raffaele, MD, Crea, Filippo, MD

“…Background Right ventricular (RV) involvement has been described in Anderson-Fabry disease (AFD), especially in patients with established Fabry cardiomyopathy…”
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Management and treatment of lactose malabsorption by Montalto, Massimo, Curigliano, Valentina, Santoro, Luca, Vastola, Monica, Cammarota, Giovanni, Manna, Raffaele, Gasbarrini, Antonio, Gasbarrini, Giovanni

“…Lactose malabsorption is a very common condition characterized by intestinal lactase deficiency. Primary lactose malabsorption is an inherited deficit present…”
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Efficacy and safety of anakinra in radiation-induced acute pericarditis: a case report by Sicignano, Ludovico Luca, Murace, Celeste Ambra, Palazzo, Antonella, Verrecchia, Elena, Massaro, Maria Grazia, Manna, Raffaele, Gerardino, Laura

“…Acute pericarditis represents an inflammatory disease affecting the pericardial layers. In developed countries more than 80% of pericarditis are defined as…”
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Coronary Artery Aneurysms Presenting as Acute Coronary Syndrome: An Unusual Case of IgG4-Related Disease Vascular Involvement by Ruggio, Aureliano, Iaconelli, Antonio, Panaioli, Elena, Bernardini, Filippo, Tinelli, Giovanni, Savino, Giancarlo, Infusino, Fabio, Leccisotti, Lucia, Manna, Raffaele, Crea, Filippo

“…We report the case of a 65-year-old man referred to our department because of a complex coronary aneurysmal disease presenting as subacute ST-segment elevation…”
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Interleukin-1 Blockers in Recurrent and Acute Pericarditis: State of the Art and Future Directions by Gallo, Antonella, Massaro, Maria Grazia, Camilli, Sara, Di Francesco, Silvino, Gerardino, Laura, Verrecchia, Elena, Sicignano, Ludovico Luca, Landi, Francesco, Manna, Raffaele, Montalto, Massimo

“…Diseases of the pericardium encompass a spectrum of conditions, including acute and recurrent pericarditis, where inflammation plays a pivotal role in the…”
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Survey about the Quality of Life of Italian Patients with Fabry Disease by Polistena, Barbara, Rigante, Donato, Sicignano, Ludovico Luca, Verrecchia, Elena, Manna, Raffaele, d’Angela, Daniela, Spandonaro, Federico

“…Fabry disease (FD) is a genetic disease included in the group of lysosomal storage disorders, caused by X-linked deficiency of the enzyme alpha-galactosidase…”
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Improvement of Liver Involvement in Familial Mediterranean Fever After the Introduction of Canakinumab: A Case Report by Massaro, Maria Grazia, Pompili, Maurizio, Sicignano, Luca L., Pizzolante, Fabrizio, Verrecchia, Elena, Vecchio, Fabio M., Rigante, Donato, Manna, Raffaele

“…Hepatic involvement in familial Mediterranean fever (FMF) ranges from a nonspecific increase in liver enzymes to cryptogenic cirrhosis, and the liver is mostly…”
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Role of Colchicine Treatment in Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS): Real-Life Data from the AIDA Network by Vitale, Antonio, Sota, Jurgen, Obici, Laura, Ricco, Nicola, Maggio, Maria Cristina, Cattalini, Marco, Ruscitti, Piero, Caso, Francesco, Manna, Raffaele, Viapiana, Ombretta, Caggiano, Valeria, Emmi, Giacomo, Insalaco, Antonella, Montin, Davide, Licciardi, Francesco, Soriano, Alessandra, Dagna, Lorenzo, Salvarani, Carlo, Lamacchia, Vittoria, Hernández-Rodríguez, José, Giacomelli, Roberto, Frediani, Bruno, Renieri, Alessandra, Cantarini, Luca

“…Objective. To analyze the potential role of colchicine monotherapy in patients with tumor necrosis factor receptor associated periodic syndrome (TRAPS) in…”
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Anti-β-Adrenoceptors Autoimmunity Causing `Idiopathic' Arrhythmias and Cardiomyopathy by Brisinda, Donatella, Sorbo, Anna Rita, Venuti, Angela, Ruggieri, Maria Pia, Manna, Raffaele, Fenici, Peter, Wallukat, Gerd, Hoebeke, Johan, Frustaci, Andrea, Fenici, Riccardo

“…Background: To determine the prevalence of anti-β-adrenoceptors autoantibodies (aβAA) in patients with idiopathic arrhythmias (IA) and to assess whether aβAA…”
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