Search Results - "Mann, Zoe F."
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Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
Published in Nature communications (29-05-2014)“…NAD is a key determinant of cellular energy metabolism. In contrast, its phosphorylated form, NADP, plays a central role in biosynthetic pathways and…”
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Characterization of the development of the mouse cochlear epithelium at the single cell level
Published in Nature communications (13-05-2020)“…Mammalian hearing requires the development of the organ of Corti, a sensory epithelium comprising unique cell types. The limited number of each of these cell…”
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3
Mitochondrial form and function in hair cells
Published in Hearing research (01-02-2023)“…•Mitochondria play a significant role in function and death of auditory hair cells.•Advances in imaging have revealed new aspects of mitochondrial…”
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Mitochondrial dynamics regulate cell morphology in the developing cochlea
Published in Development (Cambridge) (01-08-2024)“…In multicellular tissues, the size and shape of cells are intricately linked with their physiological functions. In the vertebrate auditory organ, the…”
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Gradients of glucose metabolism regulate morphogen signalling required for specifying tonotopic organization in the chicken cochlea
Published in eLife (04-08-2023)“…In vertebrates with elongated auditory organs, mechanosensory hair cells (HCs) are organised such that complex sounds are broken down into their component…”
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Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea
Published in Nature communications (20-05-2014)“…Precise frequency discrimination is a hallmark of auditory function in birds and mammals and is required for distinguishing similar sounding words, like ‘bat,’…”
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A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (20-05-2014)“…The auditory systems of animals that perceive sounds in air are organized to separate sound stimuli into their component frequencies. Individual tones then…”
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Shaping of inner ear sensory organs through antagonistic interactions between Notch signalling and Lmx1a
Published in eLife (04-12-2017)“…The mechanisms of formation of the distinct sensory organs of the inner ear and the non-sensory domains that separate them are still unclear. Here, we show…”
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Expression and function of scleraxis in the developing auditory system
Published in PloS one (13-09-2013)“…A study of genes expressed in the developing inner ear identified the bHLH transcription factor Scleraxis (Scx) in the developing cochlea. Previous work has…”
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Mitochondria modulate the spatio-temporal properties of intra- and intercellular Ca2+ signals in cochlear supporting cells
Published in Cell calcium (Edinburgh) (01-08-2009)“…Abstract In the cochlea, cell damage triggers intercellular Ca2+ waves that propagate through the glial-like supporting cells that surround receptor hair…”
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Development of tonotopy in the auditory periphery
Published in Hearing research (01-06-2011)“…Acoustic frequency analysis plays an essential role in sound perception, communication and behavior. The auditory systems of most vertebrates that perceive…”
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Response to a letter to the editor
Published in Hearing research (01-10-2011)Get full text
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13
Separation of NADPH and NADH Fluorescence Emission in Live Cells using Flim
Published in Biophysical journal (31-01-2012)Get full text
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Correction: Corrigendum: A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (01-08-2014)“…Nature Communications 5: Article number: 3839 (2014); Published: 20 May 2014; Updated: 1 August 2014. In this Article, several graphs in Fig. 2 have an…”
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Mitochondria modulate the spatio-temporal properties of intra- and intercellular Ca 2+ signals in cochlear supporting cells
Published in Cell calcium (Edinburgh) (2009)“…In the cochlea, cell damage triggers intercellular Ca 2+ waves that propagate through the glial-like supporting cells that surround receptor hair cells. These…”
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Corrigendum: A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (01-08-2014)Get full text
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