Search Results - "Mann, W R"

Long noncoding RNA functionality in imprinted domain regulation by MacDonald, William A, Mann, Mellissa R. W

“…Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription to predominantly one parental allele. Since the discovery of the…”
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Dual effects of superovulation: loss of maternal and paternal imprinted methylation in a dose-dependent manner by Market-Velker, Brenna A., Zhang, Liyue, Magri, Lauren S., Bonvissuto, Anne C., Mann, Mellissa R.W.

“…Superovulation or ovarian stimulation is currently an indispensable assisted reproductive technology (ART) for human subfertility/infertility treatment…”
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ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain by Kernohan, Kristin D., Jiang, Yan, Tremblay, Deanna C., Bonvissuto, Anne C., Eubanks, James H., Mann, Mellissa R.W., Bérubé, Nathalie G.

“…Human developmental disorders caused by chromatin dysfunction often display overlapping clinical manifestations, such as cognitive deficits, but the underlying…”
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DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages by Maatouk, Danielle M, Kellam, Lori D, Mann, Mellissa R W, Lei, Hong, Li, En, Bartolomei, Marisa S, Resnick, James L

“…DNA methylation is necessary for the silencing of endogenous retrotransposons and the maintenance of monoallelic gene expression at imprinted loci and on the X…”
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Both the folate cycle and betaine‐homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts by Zhang, Baohua, Denomme, Michelle M., White, Carlee R., Leung, Kit‐Yi, Lee, Martin B., Greene, Nicholas D. E., Mann, Mellissa R. W., Trasler, Jacquetta M., Baltz, Jay M.

“…The embryonic pattern of global DNA methylation is first established in the inner cell mass (ICM) of the mouse blastocyst. The methyl donor…”
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Selective loss of imprinting in the placenta following preimplantation development in culture by Mann, Mellissa R W, Lee, Susan S, Doherty, Adam S, Verona, Raluca I, Nolen, Leisha D, Schultz, Richard M, Bartolomei, Marisa S

“…Preimplantation development is a period of dynamic epigenetic change that begins with remodeling of egg and sperm genomes, and ends with implantation. During…”
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Genomic imprints as a model for the analysis of epigenetic stability during assisted reproductive technologies by Denomme, Michelle M, Mann, Mellissa R W

“…Gamete and early embryo development are important stages when genome-scale epigenetic transitions are orchestrated. The apparent lack of remodeling of…”
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High Frequency of Imprinted Methylation Errors in Human Preimplantation Embryos by White, Carlee R., Denomme, Michelle M., Tekpetey, Francis R., Feyles, Valter, Power, Stephen G. A., Mann, Mellissa R. W.

“…Assisted reproductive technologies (ARTs) represent the best chance for infertile couples to conceive, although increased risks for morbidities exist,…”
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Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells by Sachani, Saqib S., Landschoot, Lauren S., Zhang, Liyue, White, Carlee R., MacDonald, William A., Golding, Michael C., Mann, Mellissa R. W.

“…Genomic imprinting is a phenomenon that restricts transcription to predominantly one parental allele. How this transcriptional duality is regulated is poorly…”
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Editorial: In celebration of women in developmental epigenetics by Mann, Mellissa R W, Suzuki, Masako, Keller Valsecchi, Claudia I

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Multiple Epigenetic Modifiers Induce Aggressive Viral Extinction in Extraembryonic Endoderm Stem Cells by Golding, Michael C., Zhang, Liyue, Mann, Mellissa R.W.

“…To prevent insertional mutagenesis arising from retroviral reactivation, cells of embryonic origin possess a unique capacity to silence retroviruses. Given the…”
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Interdependent changes of nuclear lamins, nuclear pore complexes, and ploidy regulate cellular regeneration and stress response in the heart by Li, Yao, Bertozzi, Alberto, Mann, Mellissa RW, Kühn, Bernhard

“…In adult mammals, many heart muscle cells (cardiomyocytes) are polyploid, do not proliferate (post-mitotic), and, consequently, cannot contribute to heart…”
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Side-by-Side Comparison of Five Commercial Media Systems in a Mouse Model: Suboptimal In Vitro Culture Interferes with Imprint Maintenance by Market-Velker, B.A, Fernandes, A.D, Mann, M.R.W

“…Assisted reproductive technologies (ARTs) are becoming increasingly prevalent and are generally considered to be safe medical procedures. However, evidence…”
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Loss of Genomic Imprinting in Mouse Embryos with Fast Rates of Preimplantation Development in Culture by MARKET VELKER, Brenna A, DENOMME, Michelle M, MANN, Mellissa R. W

“…Currently, the stage of embryo development has been proposed as one of many criteria for identifying healthy embryos in infertility clinics with the fastest…”
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Conservation of DNA Methylation Programming Between Mouse and Human Gametes and Preimplantation Embryos by White, Carlee R, MacDonald, William A, Mann, Mellissa R W

“…In mice, assisted reproductive technologies (ARTs) applied during gametogenesis and preimplantation development can result in disruption of genomic imprinting…”
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Perturbations in imprinted methylation from assisted reproductive technologies but not advanced maternal age in mouse preimplantation embryos by Kindsfather, Audrey J, Czekalski, Megan A, Pressimone, Catherine A, Erisman, Margaret P, Mann, Mellissa R W

“…Over the last several decades, the average age of first-time mothers has risen steadily. With increasing maternal age comes a decrease in fertility, which in…”
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Embryonic imprinting perturbations do not originate from superovulation-induced defects in DNA methylation acquisition by Denomme, Michelle M., B.Sc, Zhang, Liyue, B.Sc, Mann, Mellissa R.W., Ph.D

“…Objective To investigate whether superovulation disrupts maternal imprint acquisition in oocytes. Design Animal model. Setting Academic institute. Animal(s)…”
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Domain-Specific Response of Imprinted Genes to Reduced DNMT1 by Weaver, Jamie R., Sarkisian, Garnik, Krapp, Christopher, Mager, Jesse, Mann, Mellissa R. W., Bartolomei, Marisa S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epigenetic regulation of genomic imprinting from germ line to preimplantation by MacDonald, William A., Mann, Mellissa R.W.

“…SUMMARY Genomic imprinting is an epigenetic process that distinguishes parental alleles, resulting in parent‐specific expression of a gene or cluster of genes…”
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Reprogramming of Primordial Germ Cells Begins before Migration into the Genital Ridge, Making These Cells Inadequate Donors for Reproductive Cloning by Yamazaki, Yukiko, Mellissa R. W. Mann, Lee, Susan S., Marh, Joel, McCarrey, John R., Yanagimachi, Ryuzo, Bartolomei, Marisa S.

“…Germ cells undergo epigenetic modifications as they develop, which suggests that they may be ideal donors for nuclear transfer (cloning). In this study, nuclei…”
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