Search Results - "Mann, J. R."

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas by Udugama, M., Hii, L., Garvie, A., Cervini, M., Vinod, B., Chan, F.-L., Das, P. P., Mann, J. R., Collas, P., Voon, H. P. J., Wong, L. H.

“…Alternative Lengthening of Telomeres (ALT) is a telomere maintenance pathway utilised in 15% of cancers. ALT cancers are strongly associated with inactivating…”
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Pre‐pregnancy body mass index, weight change during pregnancy, and risk of intellectual disability in children by Mann, JR, McDermott, SW, Hardin, J, Pan, C, Zhang, Z

“…Objective This study investigated pre‐pregnancy body mass index (BMI) and weight change in pregnancy as potential risk factors for intellectual disability (ID)…”
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Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer by Kurklu, B, Whitehead, R H, Ong, E K, Minamoto, T, Fox, J G, Mann, J R, Judd, L M, Giraud, A S, Menheniott, T R

“…Runt domain transcription factor 3 ( RUNX 3 ) is widely regarded as a tumour-suppressor gene inactivated by DNA hypermethylation of its canonical CpG…”
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The major determinant of exendin‐4/glucagon‐like peptide 1 differential affinity at the rat glucagon‐like peptide 1 receptor N‐terminal domain is a hydrogen bond from SER‐32 of exendin‐4 by Mann, RJ, Nasr, NE, Sinfield, JK, Paci, E, Donnelly, D

“…BACKGROUND AND PURPOSE Exendin‐4 (exenatide, Ex4) is a high‐affinity peptide agonist at the glucagon‐like peptide‐1 receptor (GLP‐1R), which has been approved…”
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Use of State Administrative Data Sources to Study Adolescents and Young Adults with Rare Conditions by Royer, J. A., Hardin, J. W., McDermott, S., Ouyang, L., Mann, J. R., Ozturk, O. D., Bolen, J.

“…ABSTRACT BACKGROUND Effective care of young people with rare conditions requires ongoing coordinated medical treatment as well as educational and social…”
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Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency by Alam, N.A., Rowan, A.J., Wortham, N.C., Pollard, P.J., Mitchell, M., Tyrer, J.P., Barclay, E., Calonje, E., Manek, S., Adams, S.J., Bowers, P.W., Burrows, N.P., Charles-Holmes, R., Cook, L.J., Daly, B.M., Ford, G.P., Fuller, L.C., Hadfield-Jones, S.E., Hardwick, N., Highet, A.S., Keefe, M., MacDonald-Hull, S.P., Potts, E.D.A., Crone, M., Wilkinson, S., Camacho-Martinez, F., Jablonska, S., Ratnavel, R., MacDonald, A., Mann, R.J., Grice, K., Guillet, G., Lewis-Jones, M.S., McGrath, H., Seukeran, D.C., Morrison, P.J., Fleming, S., Rahman, S., Kelsell, D., Leigh, I., Olpin, S., Tomlinson, I.P.M.

“…Germline mutations of the fumarate hydratase (FH, fumarase) gene are found in the recessive FH deficiency syndrome and in dominantly inherited susceptibility…”
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Survival of bacteria and spores under extreme shock pressures by Burchell, M. J., Mann, J. R., Bunch, A. W.

“…Some rocky objects on Earth originated on other planets (e.g. Martian meteorites). Modelling of interplanetary transfer times (Mars–Earth) and calculations of…”
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Caring for survivors of childhood cancers: The size of the problem by Curry, H.L., Parkes, S.E., Powell, J.E., Mann, J.R.

“…Many survivors of childhood cancer have significant health problems due to their illness or treatment. This population-based study examines the number of…”
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The United Kingdom Children’s Cancer Study Group’s Second Germ Cell Tumor Study: Carboplatin, Etoposide, and Bleomycin Are Effective Treatment for Children With Malignant Extracranial Germ Cell Tumors, With Acceptable Toxicity by MANN, J. R, RAAFAT, F, OAKHILL, A, ROBINSON, K, IMESON, J, GORNALL, P, SOKAL, M, GRAY, E, MCKEEVER, P, HALE, J, BAILEY, S

“…To evaluate carboplatin, etoposide, and bleomycin (JEB) in children with malignant extracranial germ cell tumors (GCTs). Malignant GCTs in children aged 0 to…”
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In Situ thickness measurements of chemical bath-deposited CdS by Mann, J.R., Vora, N., Repins, I.L.

“…Chemical bath-deposited (CBD) cadmium sulfide has been a component in some of the most efficient Cu(In,Ga)Se 2-based solar cell devices. While accurate in situ…”
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Factors associated with ambulatory care sensitive emergency department visits for South Carolina Medicaid members with intellectual disability by McDermott, S., Royer, J., Mann, J. R., Armour, B. S.

“…Introduction Ambulatory care sensitive conditions (ACSCs) can be seen as failure of access or management in primary care settings. Identifying factors…”
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Cellular Distribution and Developmental Expression of AMP‐Activated Protein Kinase Isoforms in Mouse Central Nervous System by Turnley, Ann M., Stapleton, David, Mann, Richard J., Witters, Lee A., Kemp, Bruce E., Bartlett, Perry F.

“…: The mammalian AMP‐activated protein kinase is a heterotrimeric serine/threonine protein kinase with multiple isoforms for each subunit (α, β, and γ) and is…”
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Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation by Bose, S, Starczynski, J, Chukwuma, M, Baumforth, K, Wei, W, Morgan, S, Byrd, P, Ying, J, Grundy, R, Mann, JR, Tao, Q, Taylor, AMR, Murray, PG, Stankovic, T

“…The tumour component of classical Hodgkin's lymphoma (cHL), Hodgkin Reed-Sternberg (HRS) cells, are believed to be derived from germinal centre (GC) B cells…”
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Congenital abnormalities and clinical features associated with Wilms’ tumour: A comprehensive study from a centre serving a large population by Ng, A, Griffiths, A, Cole, T, Davison, V, Griffiths, M, Larkin, S, Parkes, S.E, Mann, J.R, Grundy, R.G

“…Abstract Altogether 156 children treated for Wilms’ tumour (WT) between 1970 and 1998 were studied. Sixty-six children, selected only by their attendance at…”
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Chronically elevated luteinizing hormone depletes primordial follicles in the mouse ovary by FLAWS, J. A, ABBUD, R, MANN, R. J, NILSON, J. H, HIRSHFIELD, A. N

“…A few years before reproductive senescence, primordial follicles are depleted from the ovary at a dramatically accelerated rate. It has been proposed that this…”
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Sacrococcygeal teratomas: the UK Children's Cancer Study Group's experience. I. Neonatal by HUDDART, S. N, MANN, J. R, ROBINSON, K, RAAFAT, F, IMESON, J, GORNALL, P, SOKAL, M, GRAY, E, MCKEEVER, P, OAKHILL, A

“…The aim of this study was to review the United Kingdom Children's Cancer Study Group (UKCCSG) experience of sacrococcygeal teratomas (SCT) including…”
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Neuroblastomas with chromosome 11q loss and single copy MYCN comprise a biologically distinct group of tumours with adverse prognosis by LUTTIKHUIS, M. E. M. Oude, POWELL, J. E, REES, S. A, GENUS, T, CHUGHTAI, S, RAMANI, P, MCCONVILLE, C. M, MANN, J. R

“…Neuroblastoma is a heterogeneous tumour and its effective clinical management is dependent on accurate prognostic evaluation. In approximately 25% of patients…”
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Childhood cancer and parental use of tobacco: findings from the inter-regional epidemiological study of childhood cancer (IRESCC) by SORAHAN, T, MCKINNEY, P. A, MANN, J. R, LANCASHIRE, R. J, STILLER, C. A, BIRCH, J. M, DODD, H. E, CARTWRIGHT, R. A

“…Parental smoking data have been re-abstracted from the interview records of the Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC) to test…”
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A Model for the Cleft Lip Nasal Deformity by Fisher, D M, Mann, R J, Rapids, Grand

“…The underlying pathology of the cleft lip nasal deformity has yet to be fully realized, and cleft lip rhinoplasty continues to challenge the reconstructive…”
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The Consistent Association Between Epstein-Barr Virus and Hodgkin's Disease in Children in Kenya by Weinreb, M., Day, P.J.R., Niggli, F., Green, E.K., Nyong'o, A.O., Othieno-Abinya, N.A., Riyat, M.S., Raafat, F., Mann, J.R.

“…Recent studies have suggested that Epstein-Barr virus (EBV) may play a role in the etiology of Hodgkin's disease (HD). In a previous study, we used latent…”
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