Search Results - "Mann, D. M"

Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post mortem study by Taipa, Ricardo Jorge Ferreira, Ferreira, V., Brochado, P., Robinson, A, Reis, I., Marques, Fernanda, Mann, D. M., Melo-Pires, M., Sousa, Nuno

“…The association between the pathological features of AD and dementia is stronger in younger old persons than in older old persons suggesting that additional…”
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Early changes in extracellular matrix in Alzheimer's disease by Lepelletier, F.‐X., Mann, D. M. A., Robinson, A. C., Pinteaux, E., Boutin, H.

“…Aims Although changes in extracellular matrix (ECM) scaffold have been reported previously in Alzheimer's disease (AD) compared to normal ageing, it is not…”
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Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia by Snowden, J. S., Pickering-Brown, S. M., Mackenzie, I. R., Richardson, A. M. T., Varma, A., Neary, D., Mann, D. M. A.

“…Frontotemporal lobar degeneration (FTLD) refers to a focal, non-Alzheimer form of cerebral degeneration that encompasses the distinct clinical syndromes of…”
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Semiempirical model based on thermodynamic principles for determining 6 kW proton exchange membrane electrolyzer stack characteristics by Dale, N.V., Mann, M.D., Salehfar, H.

“…The performance of a 6 kW proton exchange membrane (PEM) electrolyzer was modeled using a semiempirical equation. Total cell voltage was represented as a sum…”
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Accuracy of single-photon emission computed tomography in differentiating frontotemporal dementia from Alzheimer’s disease by McNeill, R, Sare, G M, Manoharan, M, Testa, H J, Mann, D M A, Neary, D, Snowden, J S, Varma, A R

“…Background: Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are the commonest causes of presenile dementia. In the absence of a biological marker,…”
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Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy by Bowen, D. M., Procter, A. W., Mann, D. M. A., Snowden, J. S., Esiri, M. M., Neary, D., Francis, P. T.

“…Rationale Information is sparse on neurotransmitter deficiencies in frontotemporal dementia (FTD), in particular with reference to distinct histological…”
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The role of lysosomes and autophagosomes in frontotemporal lobar degeneration by Bain, H. D. C., Davidson, Y. S., Robinson, A. C., Ryan, S., Rollinson, S., Richardson, A., Jones, M., Snowden, J. S., Pickering‐Brown, S., Mann, D. M. A.

“…Introduction Cell biological and genetic evidence implicate failures in degrading aggregating proteins, such as tau and TDP‐43, through the autophagy or…”
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Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease by Allen, N., Robinson, A. C., Snowden, J., Davidson, Y. S., Mann, D. M. A.

“…Aims Pathological heterogeneity of Aβ deposition in senile plaques (SP) and cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD) has been long noted…”
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Environmental Implications of Renewable Distributed Generation Technologies in Rural Electrification by Karki, S., Mann, M. D., Salehfar, H.

“…Customer choices and competition have led the electric utilities to undergo major regulatory and technological changes while power sector reform continues. A…”
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Evaluation of the NINCDS-ADRDA criteria in the differentiation of Alzheimer’s disease and frontotemporal dementia by Varma, A R, Snowden, J S, Lloyd, J J, Talbot, P R, Mann, D M A, Neary, D

“…OBJECTIVES The diagnosis of Alzheimer’s disease (AD) is now reliant on the use of NINCDS-ADRDA criteria. Other diseases causing dementia are being increasingly…”
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Magnetic resonance imaging of fixed post mortem brains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter by McAleese, K. E., Firbank, M., Hunter, D., Sun, L., Hall, R., Neal, J. W., Mann, D. M. A., Esiri, M., Jellinger, K. A., O'Brien, J. T., Attems, J.

“…Aims Subcortical vascular pathology of the white and deep grey matter (WM and DGM) is associated with cognitive impairment. Routine neuropathological…”
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Relationships between arteriosclerosis, cerebral amyloid angiopathy and myelin loss from cerebral cortical white matter in Alzheimer's disease by Tian, J., Shi, J., Bailey, K., Mann, D. M. A.

“…Pathological relationships between damage to the deep white matter of the cerebral cortex [as evidenced by myelin loss (ML)], cerebral amyloid angiopathy (CAA)…”
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Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes by Davidson, Y. S., Robinson, A. C., Hu, Q., Mishra, M., Baborie, A., Jaros, E., Perry, R. H., Cairns, N. J., Richardson, A., Gerhard, A., Neary, D., Snowden, J. S., Bigio, E. H., Mann, D. M. A.

“…Y. S. Davidson, A. C. Robinson, Q. Hu, M. Mishra, A. Baborie, E. Jaros, R. H. Perry, N. J. Cairns, A. Richardson, A. Gerhard, D. Neary, J. S. Snowden, E. H…”
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A Prospective, Population-Based Study of the Demographics, Epidemiology, Management, and Outcome of Out-of-Hospital Pediatric Cardiopulmonary Arrest by Sirbaugh, Paul E, Pepe, Paul E, Shook, Joan E, Kimball, Kay T, Goldman, Mitchell J, Ward, Mark A, Mann, Denise M

“…Study Objectives: To perform a population-based study addressing the demography, epidemiology, management, and outcome of out-of-hospital pediatric…”
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The selective vulnerability of nerve cells in Huntington's disease by Sieradzan, K. A., Mann, D. M. A.

“…It is now more than 7 years since the genetic mutation causing Huntington's disease (HD) was first identified. Unstable CAG expansion in the IT15 gene,…”
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Preventing diabetes complications: are we too glucocentric? by Mann, D M, Woodward, M, Muntner, P

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Frontotemporal dementia with Pick‐type histology associated with Q336R mutation in the tau gene by Pickering‐Brown, S. M., Baker, M., Nonaka, T., Ikeda, K., Sharma, S., Mackenzie, J., Simpson, S. A., Moore, J. W., Snowden, J. S., de Silva, R., Revesz, T., Hasegawa, M., Hutton, M., Mann, D. M. A.

“…In this report, we describe the clinical and neuropathological features of a case of familial frontotemporal dementia (FTD), with onset at 58 years of age and…”
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The neuropathology of frontotemporal lobar degeneration with respect to the cytological and biochemical characteristics of tau protein by Taniguchi, S., McDonagh, A. M., Pickering-Brown, S. M., Umeda, Y., Iwatsubo, T., Hasegawa, M., Mann, D. M. A.

“…Pathological examinations, using a panel of tau and other antibodies, were performed on the brains from 55 consecutively acquired cases of frontotemporal lobar…”
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Inherited frontotemporal dementia in nine british families associated with intronic mutations in the tau gene by PICKERING-BROWN, S. M, RICHARDSON, A. M. T, HUTTON, M, DAVIES, Y, ALLSOP, D, CRAUFURD, D, NEARY, D, MANN, D. M. A, SNOWDEN, J. S, MCDONAGH, A. M, BURNS, A, BRAUDE, W, BAKER, M, LIU, W.-K, YEN, S.-H, HARDY, J

“…Genetic screening of 171 patients with frontotemporal lobar degeneration disclosed 14 patients, across nine pedigrees, with mutations in the intron to exon 10…”
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Synaptic changes in frontotemporal lobar degeneration: correlation with MAPT haplotype and APOE genotype by Connelly, S. J., Mukaetova-Ladinska, E. B., Abdul-All, Z., Alves da Silva, J., Brayne, C., Honer, W. G., Mann, D. M. A.

“…S. J. Connelly, E. B. Mukaetova‐Ladinska, Z. Abdul‐All, J. Alves da Silva, C. Brayne, W. G. Honer and D. M. A. Mann (2011) Neuropathology and Applied…”
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