Search Results - "Mann, Brenda K."

Efficacy of a crosslinked hyaluronic acid-based hydrogel as a tear film supplement: a masked controlled study by Williams, David L, Mann, Brenda K

“…Keratoconjunctivitis sicca (KCS), or dry eye, is a significant medical problem in both humans and dogs. Treating KCS often requires the daily application of…”
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Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines by Astashkina, Anna I, Mann, Brenda K, Prestwich, Glenn D, Grainger, David W

“…Abstract The cellular microenvironment is recognized to play a key role in stabilizing cell differentiation states and phenotypes in culture. This study…”
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Synthesis and Characterization of Novel Thiol-Reactive Poly(ethylene glycol) Cross-Linkers for Extracellular-Matrix-Mimetic Biomaterials by Vanderhooft, Janssen L, Mann, Brenda K, Prestwich, Glenn D

“…Synthetic extracellular matrix hydrogels can be used for three-dimensional cell culture, wound repair, and tissue engineering. Using the bifunctional…”
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Correction: Effect of Carboxymethylation on the Rheological Properties of Hyaluronan by Wendling, Rian J, Christensen, Amanda M, Quast, Arthur D, Atzet, Sarah K, Mann, Brenda K

“…[This corrects the article DOI: 10.1371/journal.pone.0162849.]…”
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Adhesive and mechanical properties of hydrogels influence neurite extension by Gunn, Jonathan W., Turner, Suzanne D., Mann, Brenda K.

“…Photopolymerizable polyethylene glycol (PEG) hydrogels conjugated with bioactive ligands were examined for their use as scaffolds in peripheral nerve…”
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Effect of Carboxymethylation on the Rheological Properties of Hyaluronan by Wendling, Rian J, Christensen, Amanda M, Quast, Arthur D, Atzet, Sarah K, Mann, Brenda K

“…Chemical modifications made to hyaluronan to enable covalent crosslinking to form a hydrogel or to attach other molecules may alter the physical properties as…”
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A Crosslinked HA-Based Hydrogel Ameliorates Dry Eye Symptoms in Dogs by Williams, David L., Mann, Brenda K.

“…Keratoconjunctivitis sicca, commonly referred to as dry eye or KCS, can affect both humans and dogs. The standard of care in treating KCS typically includes…”
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Mucoadhesive hyaluronic acid‐based films for vaginal delivery of metronidazole by Gerton, Marina L., Mann, Brenda K.

“…Bacterial vaginosis is a prevalent women's health issue that affects millions of women worldwide every year; however, current treatments are often messy,…”
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Topical Cross-Linked HA-Based Hydrogel Accelerates Closure of Corneal Epithelial Defects and Repair of Stromal Ulceration in Companion Animals by Williams, David L, Wirostko, Barbara M, Gum, Glenwood, Mann, Brenda K

“…The purpose of this study was to determine the safety of topical ocular administration of a cross-linked, modified hyaluronic acid (xCMHA-S) hydrogel, and its…”
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A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays by Astashkina, Anna I, Mann, Brenda K, Prestwich, Glenn D, Grainger, David W

“…Abstract Cell–cell and cell-matrix interactions control cell phenotypes and functions in viv o. Maintaining these interactions in vitro is essential to both…”
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Formulation Changes Affect Material Properties and Cell Behavior in HA-Based Hydrogels by Lawyer, Thomas, McIntosh, Kristen, Clavijo, Cristian, Potekhina, Lydia, Mann, Brenda K.

“…To develop and optimize new scaffold materials for tissue engineering applications, it is important to understand how changes to the scaffold affect the cells…”
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Mammalian cell-seeded hydrogel microarrays printed via dip-pin technology by Baird, Isaac S, Yau, Amy Y, Mann, Brenda K

“…Although significant advances have been made in the development of DNA and protein microarrays, less effort has been put toward developing mammalian cell…”
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Stereolithography of three-dimensional bioactive poly(ethylene glycol) constructs with encapsulated cells by Arcaute, Karina, Mann, Brenda K, Wicker, Ryan B

“…Stereolithography (SL) was used to fabricate complex 3-D poly(ethylene glycol) (PEG) hydrogels. Photopolymerization experiments were performed to characterize…”
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Ocular translational science: A review of development steps and paths by Mann, Brenda K., Stirland, Darren L., Lee, Hee-Kyoung, Wirostko, Barbara M.

“…Developing successful drug delivery methods is challenging for any tissue, and the eye is no exception. Translating initial concepts into advanced technologies…”
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Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering by Mann, Brenda K., Gobin, Andrea S., Tsai, Annabel T., Schmedlen, Rachael H., West, Jennifer L.

“…Photopolymerizable polyethylene glycol (PEG) derivatives have been investigated as hydrogel tissue engineering scaffolds. These materials have been modified…”
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Tethered-TGF- β increases extracellular matrix production of vascular smooth muscle cells by Mann, Brenda K, Schmedlen, Rachael H, West, Jennifer L

“…Biomaterials developed for tissue engineering and wound healing applications need to support robust cell adhesion, yet also need to be replaced by new tissue…”
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Erratum to “Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines” [Biomaterials 33 (2012) 4712–4721] by Astashkina, Anna I, Mann, Brenda K, Prestwich, Glenn D, Grainger, David W

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Single-lumen and multi-lumen poly(ethylene glycol) nerve conduits fabricated by stereolithography for peripheral nerve regeneration in vivo by Evangelista, Maristella S, Perez, Mireya, Salibian, Ara A, Hassan, Jeffrey M, Darcy, Sean, Paydar, Keyianoosh Z, Wicker, Ryan B, Arcaute, Karina, Mann, Brenda K, Evans, Gregory R D

“…The use of nerve conduits to facilitate nerve regrowth after peripheral nerve injury is limited to defects less than 3 cm. The purpose of this study is to…”
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Fabrication of Off-the-Shelf Multilumen Poly(Ethylene Glycol) Nerve Guidance Conduits Using Stereolithography by Arcaute, Karina, Mann, Brenda K, Wicker, Ryan B

“…A manufacturing process for fabricating off-the-shelf multilumen poly(ethylene glycol) (PEG)-based nerve guidance conduits (NGCs) was developed that included…”
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Effects of a Crosslinked, Modified Hyaluronic Acid (xCMHA‐S) Gel on Equine Tendon Healing by Jann, Henry W., Hart, James C. A., Stein, Larry E., Ritchey, Jerry, Blaik, Margaret, Payton, Mark, Fackelman, Gustave E., Rezabek, Grant B., Mann, Brenda K.

“…OBJECTIVE: To assess the effects of a crosslinked, modified hyaluronic acid (xCMHA‐S) gel on equine tendon healing using an in vivo surgical model. STUDY…”
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