Search Results - "Manley, Thomas"

Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities by Wolfl, Matthias, Kuball, Jürgen, Ho, William Y., Nguyen, Hieu, Manley, Thomas J., Bleakley, Marie, Greenberg, Philip D.

“…CD137 is a member of the TNFR-family with costimulatory function. Here we show that it also has many favorable characteristics as a surrogate marker for…”
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Diagnostic Accuracy of Bone Turnover Markers and Bone Histology in Patients With CKD Treated by Dialysis by Sprague, Stuart M., DO, Bellorin-Font, Ezequiel, MD, Jorgetti, Vanda, MD, PhD, Carvalho, Aluizio B., MD, PhD, Malluche, Hartmut H., MD, Ferreira, Aníbal, MD, PhD, D’Haese, Patrick C., PhD, Drüeke, Tilman B., MD, Du, Hongyan, MB, MS, Manley, Thomas, RN, CRNA, Rojas, Eudocia, MD, Moe, Sharon M., MD

“…Background The management of chronic kidney disease–mineral and bone disorder requires the assessment of bone turnover, which most often is based on…”
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Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit by Gutman, Jonathan A., Turtle, Cameron J., Manley, Thomas J., Heimfeld, Shelly, Bernstein, Irwin D., Riddell, Stanley R., Delaney, Colleen

“…We investigated the potential role of an immune reaction in mediating the dominant engraftment of 1 cord blood unit in 14 patients who received a double-unit…”
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Brentuximab Vedotin plus Chemotherapy in North American Subjects with Newly Diagnosed Stage III or IV Hodgkin Lymphoma by Ramchandren, Radhakrishnan, Advani, Ranjana H, Ansell, Stephen M, Bartlett, Nancy L, Chen, Robert, Connors, Joseph M, Feldman, Tatyana, Forero-Torres, Andres, Friedberg, Jonathan W, Gopal, Ajay K, Gordon, Leo I, Kuruvilla, John, Savage, Kerry J, Younes, Anas, Engley, Gerald, Manley, Thomas J, Fenton, Keenan, Straus, David J

“…To evaluate safety and efficacy outcomes for subjects on the ECHELON-1 study treated in North America (NA). ECHELON-1 is a global, open-label, randomized phase…”
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Brentuximab vedotin, an antibody–drug conjugate, in patients with CD30‐positive haematologic malignancies and hepatic or renal impairment by Zhao, Baiteng, Chen, Robert, O'Connor, Owen A., Gopal, Ajay K., Ramchandren, Radhakrishnan, Goy, Andre, Matous, Jeffrey V., Fasanmade, Adedigbo A., Manley, Thomas J., Han, Tae H.

“…Aims Brentuximab vedotin, an antibody–drug conjugate (ADC), selectively delivers the microtubule‐disrupting agent monomethyl auristatin E (MMAE) into…”
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T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity by Elyanow, Rebecca, Snyder, Thomas M, Dalai, Sudeb C, Gittelman, Rachel M, Boonyaratanakornkit, Jim, Wald, Anna, Selke, Stacy, Wener, Mark H, Morishima, Chihiro, Greninger, Alexander L, Gale, Jr, Michael, Hsiang, Tien-Ying, Jing, Lichen, Holbrook, Michael R, Kaplan, Ian M, Zahid, H Jabran, May, Damon H, Carlson, Jonathan M, Baldo, Lance, Manley, Thomas, Robins, Harlan S, Koelle, David M

“…BACKGROUNDMeasuring the immune response to SARS-CoV-2 enables assessment of past infection and protective immunity. SARS-CoV-2 infection induces humoral and T…”
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MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER: CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE by JASPAN, Heather B, BROTHERS, Adam W, CAMPBELL, Angela J. P, MCGUIRE, John K, BROWD, Samuel R, MANLEY, Thomas J, PAK, Daniel, WEISSMAN, Scott J

“…A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive…”
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Drifters, Drogues, and Circulation by MANLEY, THOMAS O.

“…Circulation within a body of water controls not only fluid transport, but just as importantly, chemical, biological, and sedimentological constituents…”
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Intracellular Retention of the MHC Class I-Related Chain B Ligand of NKG2D by the Human Cytomegalovirus UL16 Glycoprotein by Wu, Jennifer, Chalupny, N. Jan, Manley, Thomas J, Riddell, Stanley R, Cosman, David, Spies, Thomas

“…Infection by human CMV induces expression of the cellular MHC class I-related chain A (MICA) and chain B (MICB) surface proteins, which function as ligands for…”
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P815: HIGH VALENCY OF IGM‐2644, A CD38XCD3 IGM BISPECIFIC T CELL ENGAGER, DISPLACES DARATUMUMAB BINDING AND INDUCES POTENT MULTIPLE MYELOMA CELL KILLING by Hart, Kevin C., Santos, Daniel, Pandya, Deepal, Deng, Rong, LI, Keyu, Guan, Yinghui, Hernandez, Genevive, Manley, Thomas, Leabman, Maya K., Hinton, Paul R., Liu, Liqin, Sinclair, Angus M., Candia, Albert F., Carroll, Stephen F., Keyt, Bruce A., Kotturi, Maya F.

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Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection by Manley, Thomas J., Luy, Lisa, Jones, Thomas, Boeckh, Michael, Mutimer, Helen, Riddell, Stanley R.

“…Although cytomegalovirus (CMV) expresses proteins that interfere with antigen presentation by class I major histocompatibility complex (MHC) molecules, CD8+…”
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Comparisons of CD8+ T Cells Specific for Human Immunodeficiency Virus, Hepatitis C Virus, and Cytomegalovirus Reveal Differences in Frequency, Immunodominance, Phenotype, and Interleukin-2 Responsiveness by JAGANNATHAN, Prasanna, OSBORNE, Christine M, PIPELING, Matthew, MCDYER, John F, MANLEY, Thomas J, MEIER, Jeffery L, ALTMAN, John D, HERTEL, Laura, DAVEY, Richard T, CONNORS, Mark, MIGUELES, Stephen A, ROYCE, Cassandra, MANION, Maura M, TILTON, John C, LI LI, FISCHER, Steven, HALLAHAN, Claire W, METCALF, Julia A, MCLAUGHLIN, Mary

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Generation of HIV-1–specific CD8+ cell responses following allogeneic hematopoietic cell transplantation by Woolfrey, Ann E., Malhotra, Uma, Harrington, Robert D., McNevin, John, Manley, Thomas J., Riddell, Stanley R., Coombs, Robert W., Appelbaum, Frederick R., Corey, Larry, Storb, Rainer

“…This study tested whether donor-derived HIV-specific immune responses could be detected when viral replication was completely suppressed by the continuous…”
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Prescription patterns of long-acting β-agonist monotherapy for patients with asthma by Salmun, Luis M., MD, Wong, Mark D., PharmD, Manley, R. Thomas, BPharm, Chen, William, PhD, MPH, Bowlin, Steven J., DO, MPH, PhD

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Tracking the Surface Flow in Lake Champlain by McCormick, Michael J., Manley, Thomas O., Beletsky, Dmitry, Foley, Andrew J., Fahnenstiel, Gary L.

“…Understanding the hydrodynamics of Lake Champlain is a basic requirement for developing forecasting tools to address the lake‘s environmental issues. In 2003…”
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Nivolumab Combined With Brentuximab Vedotin for Relapsed/Refractory Primary Mediastinal Large B-Cell Lymphoma: Efficacy and Safety From the Phase II CheckMate 436 Study by Zinzani, Pier Luigi, Santoro, Armando, Gritti, Giuseppe, Brice, Pauline, Barr, Paul M, Kuruvilla, John, Cunningham, David, Kline, Justin, Johnson, Nathalie A, Mehta-Shah, Neha, Manley, Thomas, Francis, Stephen, Sharma, Manish, Moskowitz, Alison J

“…Primary mediastinal B-cell lymphoma (PMBL) is a rare but aggressive non-Hodgkin lymphoma with poor outcomes in patients with relapsed/refractory (R/R) disease…”
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Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial by Horwitz, Steven, O'Connor, Owen A, Advani, Ranjana, Rossi, Giuseppe, Kim, Won Seog, Illés, Árpád, Tobinai, Kensei, Yeh, Su-Peng, Shustov, Andrei, Yuen, Sam, Iyer, Swaminathan, Hua, Zhaowei, Little, Meredith, Rao, Shangbang, Woolery, Joseph, Manley, Thomas, Aboulafia, David, Bartlett, Nancy, Belada, David, Yehuda, Dina Ben, Benedetti, Fabio, Bordessoule, Dominique, Chang, Hung, Cheong, June Weon, Choi, Ilseung, Colita, Andrei, Congui, Angela Giovanna, Dang, Nam, Davison, Kelly, de Guibert, Sophie, Delwail, Vincent, di Raimondo, Francesco, Do, Young Rok, Domingo, Eva, Douvas, Michael, Dreyling, Martin, Fay, Keith, Ferrero, Silvia Fernandez, Flinn, Ian Winchester, Forero-Torres, Andres, Friedberg, Jonathan, Fukuhara, Noriko, Garcia-Marco, Jose, Cruz, Jorge Gayoso, Gurion, Ronit, Christensen, Jacob Haaber, Hajek, Roman, Hatake, Kiyohiko, Horowitz, Netanel, Illes, Arpad, Illidge, Tim, Ishizawa, Kenichi, Islas-Ohlmayer, Miguel, Jacobsen, Eric, Janakiram, Murali, Jurczak, Wojciech, Kaminski, Mark, Kato, Koji, Kim, Won Seog, Iyer, Swaminathan, Kuo, Ching-Yuan, Lazaroiu, Mihaela Cornelia, Lee, Jong-Seok, Lennard, Anne, LaRosee, Paul, Levi, Itai, Link, Brian, Maisonneuve, Herve, Maruyama, Dai, Mayer, Jiri, Mocikova, Heidi, Morra, Enrica, Morschhauser, Franck, Munoz, Javier, Nagai, Hirokazu, Opat, Stephen, Pettengell, Ruth, Pezzutto, Antonio, Pfreundschuh, Michael, Pro, Barbara, Reyes, Ruben, Izquierdo, Antonia Rodriguez, Rossi, Giuseppe, Ruan, Jia, Salles, Gilles, Sarriera, Jose, Shibayama, Hirohiko, Shustov, Andrei, Suh, Cheolwon, Sureda, Anna, Tanimoto, Mitsune, Taniwaki, Masafumi, Tilly, Herve, Tsukamoto, Norifumi, Wilhelm, Martin, Yamamoto, Kazuhito, Yeh, Su-Peng, Yun, Hwan Jung, Zain, Jasmine, Zinzani, Pier Luigi

“…Based on the encouraging activity and manageable safety profile observed in a phase 1 study, the ECHELON-2 trial was initiated to compare the efficacy and…”
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Clinical Validation of a Novel T-Cell Receptor Sequencing Assay for Identification of Recent or Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Dalai, Sudeb C, Dines, Jennifer N, Snyder, Thomas M, Gittelman, Rachel M, Eerkes, Tera, Vaney, Pashmi, Howard, Sally, Akers, Kipp, Skewis, Lynell, Monteforte, Anthony, Witte, Pamela R, Wolf, Cristina, Nesse, Hans, Herndon, Megan, Qadeer, Jia, Duffy, Sarah, Svejnoha, Emily, Taromino, Caroline, Kaplan, Ian M, Alsobrook, John, Manley, Thomas, Baldo, Lance

“…Abstract Background While diagnostic, therapeutic, and vaccine development in the coronavirus disease 2019 (COVID-19) pandemic has proceeded at unprecedented…”
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Real World Prevalence of Diagnostic Revision Among Patients with Peripheral T-Cell Lymphomas (PTCL) in the US: Results of an Administrative Claims and Electronic Medical Record Analyses by Feliciano, Joseph, Bonafede, Machaon, McMorrow, Donna, Park, Julie, Lisano, Julie, Manley, Thomas

“…Introduction: Peripheral T-cell lymphomas (PTCL) are a rare heterogeneous group of lymphoid malignancies, which originate from post-thymic (or mature) T-cells…”
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Defining Critical Communications Networks: Modelling Networks as Systems by Manley, Thomas, Ronning, Susan, Scheible, William

“…ABSTRACT As a society, we have become exceedingly dependent on our communication devices and the infrastructure networks supporting them. Even short duration…”
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