Search Results - "Manley, Gregory A"

Allosteric pathways in imidazole glycerol phosphate synthase by Rivalta, Ivan, Sultan, Mohammad M, Lee, Ning-Shiuan, Manley, Gregory A, Loria, J. Patrick, Batista, Victor S

“…Protein allosteric pathways are investigated in the imidazole glycerol phosphate synthase heterodimer in an effort to elucidate how the effector (PRFAR,…”
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Dissecting Dynamic Allosteric Pathways Using Chemically Related Small-Molecule Activators by Lisi, George P., Manley, Gregory A., Hendrickson, Heidi, Rivalta, Ivan, Batista, Victor S., Loria, J. Patrick

“…The allosteric mechanism of the heterodimeric enzyme imidazole glycerol phosphate synthase was studied in detail with solution nuclear magnetic resonance…”
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Determining sequential micellization steps of bile salts with multi-CMC modeling by Rovnyak, David, He, Jiayi, Kong, Sophie, Eckenroad, Kyle W., Manley, Gregory A., Geffert, Raeanne M., Krout, Michael R., Strein, Timothy G.

“…[Display omitted] Bile salts exhibit complex concentration-dependent micellization in aqueous solution, rooted in a long-standing hypothesis of increasing size…”
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Stepwise Aggregation of Cholate and Deoxycholate Dictates the Formation and Loss of Surface-Available Chirally Selective Binding Sites by Meier, Adam R, Yehl, Jenna B, Eckenroad, Kyle W, Manley, Gregory A, Strein, Timothy G, Rovnyak, David

“…Bile salts are facially amphiphilic, naturally occurring chemicals that aggregate to perform numerous biochemical processes. Because of their unique…”
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An Edge Selection Mechanism for Chirally Selective Solubilization of Binaphthyl Atropisomeric Guests by Cholate and Deoxycholate Micelles by Eckenroad, Kyle W., Manley, Gregory A., Yehl, Jenna B., Pirnie, Ross T., Strein, Timothy G., Rovnyak, David

“…Combining micellar electrokinetic capillary chromatography (MEKC) and nuclear magnetic resonance (NMR) experimentation, we shed light on the structural basis…”
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Accelerating multidimensional NMR and MRI experiments using iterated maps by Frey, Merideth A., Sethna, Zachary M., Manley, Gregory A., Sengupta, Suvrajit, Zilm, Kurt W., Loria, J. Patrick, Barrett, Sean E.

“…[Display omitted] •An iterated maps algorithm is applied to sparsely-sampled time domain data.•Used to reconstruct spectra from noisy 2D NMR and 3D MRI of…”
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Sodium Cholate Aggregation and Chiral Recognition of the Probe Molecule (R,S)-1,1′-Binaphthyl-2,2′-diylhydrogenphosphate (BNDHP) Observed by 1H and 31P NMR Spectroscopy by Hebling, Christine M, Thompson, Laura E, Eckenroad, Kyle W, Manley, Gregory A, Fry, Roderick A, Mueller, Karl T, Strein, Timothy G, Rovnyak, David

“…Bile salt micelles can be employed as a pseudostationary phase in micellar electrokinetic capillary chromatography (MEKC) separations of chiral analytes. To…”
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Allosteric inhibition of individual enzyme molecules trapped in lipid vesicles by Piwonski, Hubert M, Goomanovsky, Mila, Bensimon, David, Horovitz, Amnon, Haran, Gilad

“…Enzymatic inhibition by product molecules is an important and widespread phenomenon. We describe an approach to study product inhibition at the single-molecule…”
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Allosteric pathways in imidazole glycerol phosphate synthase by Rivalta, Ivan, Sultan, Mohammad M., Lee, Ning-Shiuan, Manley, Gregory A., Loria, J. Patrick, Batista, Victor S.

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Sodium Cholate Aggregation and Chiral Recognition of the Probe Molecule ( R , S )-1,1′-Binaphthyl-2,2′-diylhydrogenphosphate (BNDHP) Observed by 1 H and 31 P NMR Spectroscopy by Hebling, Christine M., Thompson, Laura E., Eckenroad, Kyle W., Manley, Gregory A., Fry, Roderick A., Mueller, Karl T., Strein, Timothy G., Rovnyak, David

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