Search Results - "Manjunath D"
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Recent advances in the discovery of small molecule c-Met Kinase inhibitors
Published in European journal of medicinal chemistry (01-01-2018)“…c-Met is a prototype member of a subfamily of heterodimeric receptor tyrosine kinases (RTKs) and is the receptor for hepatocyte growth factor (HGF). Binding of…”
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On the Whittle Index for Restless Multiarmed Hidden Markov Bandits
Published in IEEE transactions on automatic control (01-09-2018)“…We consider a restless multiarmed bandit in which each arm can be in one of two states. When an arm is sampled, the state of the arm is not available to the…”
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Sponsored Data: On the Effect of ISP Competition on Pricing Dynamics and Content Provider Market Structures
Published in IEEE/ACM transactions on networking (01-10-2022)“…We analyze the effect of sponsored data when Internet service providers (ISPs) compete for subscribers and content providers (CPs) compete for a share of the…”
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Revenue maximization in service systems with heterogeneous customers
Published in European journal of operational research (16-10-2019)“…•We identify Wardrop equilibrium routing for the two server system with admission fee.•We identify the revenue maximizing price for the monopoly system.•We…”
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Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors
Published in European journal of medicinal chemistry (03-03-2014)“…Dipeptidyl peptidase-4 (DPP-4) is one of the widely explored novel targets for Type 2 diabetes mellitus (T2DM) currently. Research has been focused on the…”
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Ionic Pairing and Selective Solvation of Butylmethylimidazolium Chloride Ion Pairs in DMSO–Water Mixtures: A Comprehensive Examination via Molecular Dynamics Simulations and Potentials of Mean Force Analysis
Published in The journal of physical chemistry. B (07-03-2024)“…Ionic liquids (ILs) with dimethyl sulfoxide (DMSO) and water act as a promising solvent medium for the dissolution of cellulose in an efficient manner. To…”
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Histone deacetylase 2: A potential therapeutic target for cancer and neurodegenerative disorders
Published in European journal of medicinal chemistry (15-04-2021)“…Histone deacetylases (HDACs) have been implicated in a number of diseases including cancer, cardiovascular disorders, diabetes mellitus, neurodegenerative…”
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Zero Rating: The Power in the Middle
Published in IEEE/ACM transactions on networking (01-04-2019)“…Many flavors of differential data pricing are being practiced in different telecom markets. One popular version is zero-rating, where customers do not pay for…”
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Bioinspired quantum dots for cancer therapy: A mini-review
Published in Materials letters (15-04-2022)“…[Display omitted] •An overview of bioinspired Quantum Dots (QDs).•Utility of bioinspired QDs for drug delivery applications for combating cancer.•Future…”
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Deep Learning-Based Improved WCM Technique for Soil Moisture Retrieval with Satellite Images
Published in Remote sensing (Basel, Switzerland) (01-04-2023)“…The water cycle around the globe is significantly impacted by the moisture in the soil. However, finding a quick and practical model to cope with the enormous…”
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Towards a Distributed Caching Service at the WiFi Edge Using Wi-Cache
Published in IEEE eTransactions on network and service management (01-12-2021)“…Caching content close to the end users, e.g., at cellular base stations (BSs), WiFi access points (APs), and end user devices is known to improve efficiency…”
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Optimal Embedding of Functions for In-Network Computation: Complexity Analysis and Algorithms
Published in IEEE/ACM transactions on networking (01-08-2016)“…We consider optimal distributed computation of a given function of distributed data. The input (data) nodes and the sink node that receives the function form a…”
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On the Economics Effects of CDN-Mediated Delivery on Content Providers
Published in IEEE eTransactions on network and service management (01-12-2022)“…Content delivery networks (CDNs) have been providing the key engineering and economic mediation between content providers (CPs) and Internet service providers…”
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On the Economics of Network Interconnections and its Impact on Net Neutrality
Published in IEEE eTransactions on network and service management (01-12-2021)“…The Internet of symmetric traffic flows between networks and a hierarchical topology, has long given way to one with significantly asymmetric traffic flows and…”
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Medicinal chemistry strategies for the development of phosphodiesterase 10A (PDE10A) inhibitors - An update of recent progress
Published in European journal of medicinal chemistry (15-03-2021)“…Phosphodiesterase 10A is a member of Phosphodiesterase (PDE)-superfamily of the enzyme which is responsible for hydrolysis of cAMP and cGMP to their inactive…”
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Novel research strategies of benzimidazole derivatives: a review
Published in Mini reviews in medicinal chemistry (01-08-2013)“…Benzimidazole plays an important role in the medicinal chemistry and drug discovery with many pharmacological activities which have made an indispensable…”
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On Index Coded Video Delivery at the WiFi Edge: Performance and System Design
Published in IEEE eTransactions on network and service management (01-06-2022)“…Coded delivery has been found to improve content delivery by reducing the data transmitted over a broadcast network. The existing works are mostly theoretical,…”
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In-silico identification and exploration of small molecule coumarin-1,2,3-triazole hybrids as potential EGFR inhibitors for targeting lung cancer
Published in Molecular diversity (12-03-2024)“…Globally, lung cancer is a significant public health concern due to its role as the leading cause of cancer-related mortalities. The promising target of EGFR…”
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Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors
Published in Bioorganic chemistry (01-06-2017)“…[Display omitted] •A series of substituted [1,2,4]triazolo[5,1-c][1,2,4]triazine derivatives was synthesized.•Compound 15q showed 28.05μM DPP-4 IC50 during in…”
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Multi-spectroscopic investigation of the binding interaction of fosfomycin with bovine serum albumin
Published in Journal of pharmaceutical analysis (01-08-2015)“…The interaction between fosfomycin (FOS) and bovine serum albumin (BSA) has been investigated ef- fectively by multi-spectroscopic techniques under…”
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