Search Results - "Manjubala, I."
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1
Effectiveness of zebrafish models in understanding human diseases—A review of models
Published in Heliyon (01-03-2023)“…Understanding the detailed mechanism behind every human disease, disorder, defect, and deficiency is a daunting task concerning the clinical diagnostic tools…”
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2
Synergistic combination of baicalein and rifampicin against Staphylococcus aureus biofilms
Published in Frontiers in microbiology (06-08-2024)“…, a Gram-positive bacterium, is a predominant pathogen associated with various infections. The rapid emergence of antibiotic resistance has intensified the…”
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3
Commercial hydrogels for biomedical applications
Published in Heliyon (01-04-2020)“…Hydrogels are polymeric networks having the ability to absorb a large volume of water. Flexibility, versatility, stimuli-responsive, soft structure are the…”
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4
An in-silico approach to the potential modulatory effect of taurine on sclerostin (SOST) and its probable role during osteoporosis
Published in Journal of biomolecular structure & dynamics (21-11-2024)“…The cysteine-knot containing negative regulator of the Wnt (Wingless-related integration site) signaling pathway, sclerostin (SOST) is an emerging therapeutic…”
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5
Identification of potential sclerostin inhibiting flavonoids from Oroxylum indicum: an insilico approach
Published in Journal of biomolecular structure & dynamics (01-09-2024)“…Flavonoids are secondary metabolites that are widely found in various medicinal plants. They are known for their medicinal benefits and have been extensively…”
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Probing the effects of single point mutations in the GKWWRPS motif on the PNAIG motif within Loop 2 of sclerostin (SOST) using in-silico techniques
Published in Computational biology and chemistry (01-10-2024)“…Sclerostin (SOST), a Wnt signaling pathway inhibitor, is involved in the pathogenesis of skeletal disorders. This study investigated the impact of the GKWWRPS…”
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Elucidating anti-sclerostin mechanism of baicalein using LRP6-Sclersotin complex of canonical Wnt/β-catenin signaling pathway
Published in Journal of biomolecular structure & dynamics (19-01-2024)“…Flavonoids are polyphenolic compounds produced by plants as secondary metabolites that are known to exhibit wide range of pharmaceutical properties. Flavonoids…”
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8
PEO–CMC blend nanofibers fabrication by electrospinning for soft tissue engineering applications
Published in Materials letters (15-05-2017)“…Caboxy methyl cellulose (CMC) is a biocompatible polymer, widely used in food and pharma industries for coatings and in wound care applications. To explore its…”
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Type I collagen peptides and nitric oxide releasing electrospun silk fibroin scaffold: A multifunctional approach for the treatment of ischemic chronic wounds
Published in Colloids and surfaces, B, Biointerfaces (01-03-2019)“…[Display omitted] •Electrospun SF-PVA nanofibrous scaffold functionalized with collagen peptide and GSNO for wound healing application.•Type I collagen…”
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10
In situ synthesis of hydroxyapatite/carboxymethyl cellulose composites for bone regeneration applications
Published in Colloid and polymer science (01-10-2018)“…The study of inorganic hydroxyapatite (HA) assembly in polymer matrix is of great interest in bone tissue engineering field. An in situ synthesis method is…”
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11
The influence of molecular weight of cellulose on the properties of carboxylic acid crosslinked cellulose hydrogels for biomedical and environmental applications
Published in International journal of biological macromolecules (01-06-2023)“…Hydrogels a three-dimensional network structure of hydrophilic polymers have gained significant interest in the field of biomedicine due to its high-water…”
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12
Thermal behavior of carboxymethyl cellulose in the presence of polycarboxylic acid crosslinkers
Published in Journal of thermal analysis and calorimetry (01-10-2019)“…Cellulose is the most abundant biopolymer and with different chemical modification products yields excellent properties like high viscosity, hydrophilicity,…”
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13
Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral
Published in Bone (New York, N.Y.) (01-12-2011)“…Abstract In the present study a rat animal model of lathyrism was employed to decipher whether anatomically confined alterations in collagen cross-links are…”
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14
Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing
Published in Bone (New York, N.Y.) (01-08-2009)“…Abstract After bone fracture, various cellular activities lead to the formation of different tissue types, which form the basis for the process of secondary…”
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Mineralisation of chitosan scaffolds with nano-apatite formation by double diffusion technique
Published in Acta biomaterialia (2006)“…The study of inorganic crystal assembly in organic matrices has given rise to increasing interest in various fields of materials science to the natural process…”
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16
In vitro bioactivity of bioresorbable porous polymeric scaffolds incorporating hydroxyapatite microspheres
Published in Acta biomaterialia (01-07-2010)“…Biomimetic composites consisting of polymer and mineral components, resembling bone in structure and composition, were produced using a rapid prototyping…”
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17
Raman imaging of two orthogonal planes within cortical bone
Published in Bone (New York, N.Y.) (01-09-2007)“…Abstract The lamellar bone's strength is mainly affected by the organization of its mineralized collagen fibers and material composition. In the present study,…”
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Fetal and postnatal mouse bone tissue contains more calcium than is present in hydroxyapatite
Published in Journal of structural biology (01-11-2011)“…It has been shown for developing enamel and zebrafish fin that hydroxyapatite (HA) is preceded by an amorphous precursor, motivating us to examine the mineral…”
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19
Development of keratin–chitosan–gelatin composite scaffold for soft tissue engineering
Published in Materials Science & Engineering C (01-12-2014)“…Keratin has gained much attention in the recent past as a biomaterial for wound healing owing to its biocompatibility, biodegradability, intrinsic biological…”
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Growth of osteoblast-like cells on biomimetic apatite-coated chitosan scaffolds
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-01-2008)“…Porous scaffold materials that can provide a framework for the cells to adhere, proliferate, and create extracellular matrix are considered to be suitable…”
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