Search Results - "Maniyar, Rachana R"

Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism by He, Changhao, Maniyar, Rachana R, Avraham, Yahel, Zappasodi, Roberta, Rusinova, Radda, Newman, Walter, Heath, Heidi, Wolchok, Jedd D, Dahan, Rony, Merghoub, Taha, Meyerson, Joel R

“…GITR is a TNF receptor, and its activation promotes immune responses and drives antitumor activity. The receptor is activated by the GITR ligand (GITRL), which…”
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Abstract 2365: Checkpoint inhibitors and a multivalent melanoma vaccine as a novel combinatorial therapy by Maniyar, Rachana R., Tuli, Neha, Suriano, Robert, Geliebter, Jan, Wallack, Marc, Tiwari, Raj K.

“…Abstract Over 1 million cases of skin cancer are diagnosed in the US every year, of which 75% deaths result due to melanoma, one of the deadliest forms of skin…”
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Abstract 3263: Dietary supplement 3, 3’-diindolylmethane (DIM) as an antiangiogenic agent in breast cancer by Ben Rahoma, Ghada M., Tuli, Neha Y., Bednarczyk, Robert B., Maniyar, Rachana R., Mittelman, Abraham, Geliebter, Jan, Tiwari, Raj

“…Abstract Tumor angiogenesis refers to the sprouting and cooption of proliferating endothelial cells (EC’s) from adjacent pre-existing host vasculature, and is…”
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Abstract 1624: Novel immune targets in melanoma by profiling of co-activators and co-receptors by Jarboe, Tara, Maniyar, Rachana R., Chakraborty, Sanjukta, Degliuomini, John J., Srinivasan, Anitha, Wallack, Marc, Geliebter, Jan, Tiwari, Raj K.

“…Abstract Melanoma, the most aggressive form of skin cancer, is still a challenge despite the advent of recent immunotherapies using checkpoint inhibitors. The…”
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Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism by He, Changhao, Maniyar, Rachana R., Avraham, Yahel, Zappasodi, Roberta, Rusinova, Radda, Newman, Walter, Heath, Heidi, Wolchok, Jedd D., Dahan, Rony, Merghoub, Taha, Meyerson, Joel

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Abstract 3237: Combinatorial immune checkpoint inhibitor therapy in anaplastic thyroid cancer by Chakraborty, Sanjukta, Maniyar, Rachana R., Dadafarin, Sina, Rahoma, Ghada Ben, Singh, Sarnath, Moscatello, Augustine, Geliebter, Jan, Tiwari, Raj K.

“…Abstract Anaplastic thyroid cancer(ATC) is a rare but extremely aggressive form of endocrine malignancy that accounts for only 1-2% of total thyroid cancer…”
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Abstract 3946: Tumor checkpoint inhibitor profiling for an optimal clinical response by Maniyar, Rachana R., Chakraborty, Sanjukta, Rahoma, Ghada Ben, Degliuomini, John J., Wallack, Marc, Geliebter, Jan, Tiwari, Raj K.

“…Abstract The last three decades have seen a steady rise in melanoma, the most aggressive form of skin cancer. The discovery of checkpoint inhibitors has…”
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Abstract 714: A case for combining immunotherapy and targeted small molecule inhibitors: Immunoregulation by primary melanoma cells by Maniyar, Rachana R., Chakraborty, Sanjukta, Tuli, Neha Y., Rahoma, Ghada Ben, Singh, Sarnath, Wallack, Marc, Geliebter, Jan, Tiwari, Raj K.

“…Abstract Metastatic melanoma, leads to the highest number of skin cancer related deaths. Checkpoint inhibitor therapy has witnessed a high success rate in…”
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Abstract 4034: Lag3 blockade enhances the anti-tumor effect of dual GITR agonism and PD-1 blockade in a preclinical melanoma model by Maniyar, Rachana R., Elhanati, Yuval, Mangarin, Levi, Marouf, Yacine, Ahmed, Ashley, Greenbaum, Benjamin, Wolchok, Jedd, Merghoub, Taha

“…Abstract Immune checkpoint blockade (ICB) therapies, specifically anti PD-1 and anti CTLA-4, have resulted in tremendous success in the clinic. However, a…”
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Abstract 3656: Implication for checkpoint therapeutics: Expression of co-stimulatory and co-inhibitory molecules in melanoma cells by Maniyar, Rachana R., Chakraborty, Sanjukta, Tuli, Neha, Rahoma, Ghada Ben, Singh, Sarnath, Geliebter, Jan, Wallack, Marc, Tiwari, Raj K.

“…Abstract Melanoma is one of the deadliest forms of skin cancer, with a dim prognosis when metastasized, leading to the highest number of skin cancer related…”
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Abstract 5676: Functional pairing of immunomodulatory targets in anaplastic thyroid cancer by Chakraborty, Sanjukta, Maniyar, Rachana R., Tuli, Neha Y., Rahoma, Ghada Ben, Budenz, Cameron, Singh, Sarnath, Geliebter, Jan, Tiwari, Raj

“…Abstract Thyroid cancer is the most common type of endocrine malignancy that has an escalating global frequency. Although most well differentiated thyroid…”
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Abstract 2762: Identification of novel immunotherapeutic targets in anaplastic thyroid cancer by Chakraborty, Sanjukta, Maniyar, Rachana R., Tuli, Neha Y., Rahoma, Ghada Ben, Singh, Sarnath, Kamat, Ameet, Berzofsky, Craig, Budenz, Cameron, Moscatello, Augustine, Geliebter, Jan, Tiwari, Raj K.

“…Abstract Thyroid cancer is the most rapidly increasing cancer in the US with anaplastic thyroid cancer (ATC) being the rarest and most aggressive form. ATC…”
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Abstract 3365: Provasculogenic effects of alcohol and estrogen: implications for breast cancer development by Maniyar, Rachana R., Bednarczyk, Robert B., Ben Rahoma, Ghada M., Tuli, Neha, Mittelman, Abraham, Tiwari, Raj K., Suriano, Robert

“…Abstract Over 200,000 cases of breast cancer are diagnosed within the United States, resulting in over 40,000 deaths annually. Of the many lifestyle habits…”
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