Search Results - "Manivet, P"

'Desperate house genes': the dramatic example of hypoxia by Caradec, J, Sirab, N, Keumeugni, C, Moutereau, S, Chimingqi, M, Matar, C, Revaud, D, Bah, M, Manivet, P, Conti, M, Loric, S

“…Background: Microenvironmental conditions in normal or tumour tissues and cell lines may interfere on further biological analysis. To evaluate transcript…”
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Prognostic value of prostate circulating cells detection in prostate cancer patients: a prospective study by Eschwège, P, Moutereau, S, Droupy, S, Douard, R, Gala, J-L, Benoit, G, Conti, M, Manivet, P, Loric, S

“…In clinically organ-confined prostate cancer patients, bloodstream tumour cell dissemination generally occurs, and may be enhanced by surgical prostate…”
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Computational approaches for the study of serotonin and its membrane transporter SERT: implications for drug design in neurological sciences by Pratuangdejkul, J, Schneider, B, Launay, J-M, Kellermann, O, Manivet, P

“…Serotonin (5-hydroxytryptamine, 5-HT), a monoamine neurotransmitter of the central nervous and peripheral systems (CNS), plays a critical role in a wide…”
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Definition of an uptake pharmacophore of the serotonin transporter through 3D-QSAR analysis by Pratuangdejkul, J, Schneider, B, Jaudon, P, Rosilio, V, Baudoin, E, Loric, S, Conti, M, Launay, J-M, Manivet, P

“…The serotonergic system plays a critical role in a wide variety of physiological and behavioral processes. Dysregulation of the tightly controlled…”
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Identification of three novel mutations (E196K, V203I, E211Q) in the prion protein gene (PRNP) in inherited prion diseases with Creutzfeldt-Jakob disease phenotype by Peoc'h, Katell, Manivet, Philippe, Beaudry, Patrice, Attane, Françoise, Besson, Gérard, Hannequin, Didier, Delasnerie-Lauprêtre, Nicole, Laplanche, Jean-Louis

“…Inherited prion diseases are characterized by mutations in the PRNP gene encoding the prion protein (PrP). As the other sporadic or infectious prion disease…”
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Ligand interaction with the purified serotonin transporter in solution and at the air/water interface by Faivre, V., Manivet, P., Callaway, J.C., Airaksinen, M.M., Morimoto, H., Baszkin, A., Launay, J.M., Rosilio, V.

“…The purified serotonin transporter (SERT) was spread at the air/water interface and the effects both of its surface density and of the temperature on its…”
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Signaling Pathways and Targets of the 5-HT2B Receptor in the 1C11 Serotonergic Cell Line by KELLERMANN, O., TOURNOIS, C., RICHARD, S., MANIVET, P., MAROTEAUX, L., LAUNAY, J. M.

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Specific interactions between the human serotonin transporter and serotonin analogs at the solution/air interface by Dalençon, F., Rosilio, V., Manivet, P., Launay, J.-M., Baszkin, A.

“…Purified serotonin transporter protein (SERT) was spread at the buffer solution/air interface. The monolayers appeared to be stable and exhibited an inflection…”
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Histological, immunohistochemical, ultrastructural and biochemical study of human gastric composite tumor: expression of the serotonin-2B receptor by the neuroendocrine component by Brouland, J P, Manivet, P, Brocheriou-Spelle, I, Wassef, M, Le Bodic, M F, Lavergne, A, Launay, J M

“…We report a case of a human gastric composite tumor occurring seven years after a partial gastrectomy for a low grade B cell MALT lymphoma. Histological…”
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Sonic Hedgehog–dependent proliferation in a series of patients with colorectal cancer by Douard, Richard, Moutereau, Stéphane, Pernet, Pascal, Chimingqi, Mihelaiti, Allory, Yves, Manivet, Philippe, Conti, Marc, Vaubourdolle, Michel, Cugnenc, Paul-Henri, Loric, Sylvain

“…The Hedgehog ( Hh) gene family is known to regulate development of stem cells. In addition, activation is responsible for the induction of GLI1 proto-oncogene…”
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Urinary cystatin C as a specific marker of tubular dysfunction by Conti, Marc, Moutereau, Stéphane, Zater, Mokhtar, Lallali, Karim, Durrbach, Antoine, Manivet, Philippe, Eschwège, Pascal, Loric, Sylvain

“…Cystatin C (CST3), a strong inhibitor of cysteine proteinases, is freely filtered by the kidney glomerulus and is reabsorbed by the tubules, where it is almost…”
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538 PAR1 differential expression as a biomarker of prostate cancer progression by El, Atmani A, Caradec, J, Nicolaiew, N, Allory, Y, De La Taille, A, Vacherot, F, Eschwege, P, Manivet, P, Kouyoumdjian, J.C, Loric, S

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In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part I: beyond the reduction of animal model use by Huynh, Lucie, Masereeuw, Rosalinde, Friedberg, Thomas, Ingelman-Sundberg, Magnus, Manivet, Philippe

“…There is an urgent need for efficient in silico ADME-T prediction tools for the selection of potent therapeutic drugs as well as the elimination of toxic…”
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Ablation of serotonin 5-HT2B receptors in mice leads to abnormal cardiac structure and function by NEBIGIL, Canan G, HICKEL, Pierre, LAUNAY, Jean-Marie, MAROTEAUX, Luc, MESSADDEQ, Nadia, VONESCH, Jean-Luc, DOUCHET, Marie P, MONASSIER, Laurent, GYÖRGY, Katalin, MATZ, Rachel, ANDRIANTSITOHAINA, Ramaroson, MANIVET, Philippe

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The serotonin binding site of human and murine 5-HT2B receptors: molecular modeling and site-directed mutagenesis by Manivet, Philippe, Schneider, Benoit, Smith, Jeremy Christopher, Choi, Doo-Sup, Maroteaux, Luc, Kellermann, Odile, Launay, Jean-Marie

“…Bacteriorhodopsin and rhodopsin crystal structures were used as templates to build structural models of the mouse and human serotonin (5-HT)-2B receptors…”
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PDZ-dependent Activation of Nitric-oxide Synthases by the Serotonin 2B Receptor by Manivet, Philippe, Mouillet-Richard, Sophie, Callebert, Jacques, Nebigil, Canan G., Maroteaux, Luc, Hosoda, Syun, Kellermann, Odile, Launay, Jean-Marie

“…Taking advantage of three cellular systems, we established that 5-HT2B receptors are coupled with NO signaling pathways. In the 1C11 serotonergic cell line…”
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Identification of the binding sites and selectivity of sarpogrelate, a novel 5-HT2 antagonist, to human 5-HT2A, 5-HT2B and 5-HT2C receptor subtypes by molecular modeling by Rashid, Mamunur, Manivet, Philippe, Nishio, Hiroaki, Pratuangdejkul, Jaturong, Rajab, Mazen, Ishiguro, Masaji, Launay, Jean Marie, Nagatomo, Takafumi

“…The aim of the present study was to investigate the binding sites interactions and the selectivity of sarpogrelate to human 5-HT(2) receptor family (5-HT(2A),…”
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Cation-π Interactions in Serotonin:  Conformational, Electronic Distribution, and Energy Decomposition Analysis by Pratuangdejkul, Jaturong, Jaudon, Pascale, Ducrocq, Claire, Nosoongnoen, Wichit, Guerin, Georges-Alexandre, Conti, Marc, Loric, Sylvain, Launay, Jean-Marie, Manivet, Philippe

“…An adiabatic conformational analysis of serotonin (5-hydroxytryptamine, 5-HT) using quantum chemistry led to six stable conformers that can be either +gauche…”
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Absence of circadian variations in urine cystatin C allows its use on urinary samples by Conti, Marc, Zater, Mokhtar, Lallali, Karim, Durrbach, Antoine, Moutereau, Stéphane, Manivet, Philippe, Eschwège, Pascal, Loric, Sylvain

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Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity by Lanone, Sophie, Manivet, Philippe, Callebert, Jacques, Launay, Jean-Marie, Payen, Didier, Aubier, Michel, Boczkowski, Jorge, Mebazaa, Alexandre

“…Tyrosine nitration is a post-translational protein modification with potentially significant biological implications. In the present study we demonstrate, for…”
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