Search Results - "Maniecki, Maciej B."
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Identification of the receptor scavenging hemopexin-heme complexes
Published in Blood (01-10-2005)“…Heme released from heme-binding proteins on internal hemorrhage, hemolysis, myolysis, or other cell damage is highly toxic due to oxidative and proinflammatory…”
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A soluble form of the macrophage-related mannose receptor (MR/CD206) is present in human serum and elevated in critical illness
Published in Clinical chemistry and laboratory medicine (01-03-2014)“…This study tests the hypothesis that the mannose receptor (MR/CD206), which is expressed primarily by macrophages and dendritic cells, can be found in a…”
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Assessing the potential cost-effectiveness of centralised versus point-of-care testing for hepatitis C virus in Pakistan: a model-based comparison
Published in BMJ open (04-05-2023)“…ObjectivesPakistan has a hepatitis C virus (HCV) infection prevalence of 6%–9% and aims to achieve World Health Organisation (WHO) targets for elimination of…”
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Monocyte/macrophage-derived soluble CD163: a novel biomarker in multiple myeloma
Published in European journal of haematology (01-07-2014)“…Objectives Macrophages play an important role in cancer by suppression of adaptive immunity and promotion of angiogenesis and metastasis. Tumor‐associated…”
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Monocyte/macrophage‐derived soluble CD 163: a novel biomarker in multiple myeloma
Published in European journal of haematology (01-07-2014)Get full text
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Abstract 1534: CD163-expressing macrophages constitute a distinct malignancy-promoting phenotype in melanoma facilitating tumor development, progression, and metastasis: Implications for novel anticancer therapy
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Tumor-infiltrating macrophages are recruited to the tumor microenvironment and believed to play a key role in tumor development, progression, and metastasis by…”
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Abstract 539: The expression of monocyte/macrophage-restricted scavenger receptor CD163 by malignant cells may be a consequence of cell fusion with tumor-associated macrophages: A novel target for cancer therapy
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Solid tumors contain large a number of infiltrating macrophages, which are believed to play a key role in progression and metastasis. Recent research has…”
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Abstract 1354: Expression of macrophage scavenger receptor (CD163) by tumor-infiltrating macrophages and malignant cells in bladder cancer: association with disease severity and poor patient survival
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Introduction: Infiltrating cells of the tumor microenvironment are important for the growth and spreading of cancer. CD163 is a macrophage-specific hemoglobin…”
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Impaired CD163 Mediated Hemoglobin-Scavenging and Hemolytic Crisis in Patients Treated with CD33 Targeted Chemotherapy (Gemtuzumab Ozogamicin, Mylotarg™)
Published in Blood (16-11-2007)“…Hemoglobin liberated to plasma during intravascular hemolyses is rapidly bound to haptoglobin. The hemoglobin-haptoglobin complexes undergo endocytosis through…”
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Identification of the receptor scavenging hemopexin-heme complexes. Commentary
Published in Blood (2005)Get full text
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