Search Results - "Manich, Gemma"

Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease by Augé, Elisabet, Pelegrí, Carme, Manich, Gemma, Cabezón, Itsaso, Guinovart, Joan J., Duran, Jordi, Vilaplana, Jordi

“…Lafora disease (LD), the most devastating adolescence‐onset epilepsy, is caused by mutations in the EPM2A or EPM2B genes, which encode the proteins laforin and…”
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Deciphering the Genetic Crosstalk between Microglia and Oligodendrocyte Precursor Cells during Demyelination and Remyelination Using Transcriptomic Data by Enrich-Bengoa, Jennifer, Manich, Gemma, Dégano, Irene R, Perálvarez-Marín, Alex

“…Demyelinating disorders show impaired remyelination due to failure in the differentiation of oligodendrocyte progenitor cells (OPCs) into mature myelin-forming…”
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Histone deacetylase inhibition by suberoylanilide hydroxamic acid during reperfusion promotes multifaceted brain and vascular protection in spontaneously hypertensive rats with transient ischaemic stroke by Díaz-Pérez, Andrea, Pérez, Belén, Manich, Gemma, García-Aranda, Julián, Navarro, Xavier, Penas, Clara, Jiménez-Altayó, Francesc

“…Hypertension is the most prevalent modifiable risk factor for stroke and is associated with worse functional outcomes. Pharmacological inhibition of histone…”
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Periodic acid-Schiff granules in the brain of aged mice: from amyloid aggregates to degenerative structures containing neo-epitopes by Manich, Gemma, Cabezón, Itsaso, Augé, Elisabet, Pelegrí, Carme, Vilaplana, Jordi

“…Highlights • PAS granules are degenerative structures formed in mice brain with age. • Oxidative stress and genetic background play a significant role in…”
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TRPV2: A Key Player in Myelination Disorders of the Central Nervous System by Enrich-Bengoa, Jennifer, Manich, Gemma, Valente, Tony, Sanchez-Molina, Paula, Almolda, Beatriz, Solà, Carme, Saura, Josep, González, Berta, Castellano, Bernardo, Perálvarez-Marín, Alex

“…Transient potential receptor vanilloid 2 (TRPV2) is widely expressed through the nervous system and specifically found in neuronal subpopulations and some…”
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Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies by Manich, Gemma, Augé, Elisabet, Cabezón, Itsaso, Pallàs, Mercè, Vilaplana, Jordi, Pelegrí, Carme

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Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models by Manich, Gemma, Gómez-López, Ariadna Regina, Almolda, Beatriz, Villacampa, Nàdia, Recasens, Mireia, Shrivastava, Kalpana, González, Berta, Castellano, Bernardo

“…Microglia are the main immune cells of the central nervous system (CNS), and they are devoted to the active surveillance of the CNS during homeostasis and…”
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Ambient temperature and prevalence of obesity in the Spanish population: The Di@bet.es study by Valdés, Sergio, Maldonado‐Araque, Cristina, García‐Torres, Francisca, Goday, Alberto, Bosch‐Comas, Ana, Bordiú, Elena, Calle‐Pascual, Alfonso, Carmena, Rafael, Casamitjana, Roser, Castaño, Luis, Castell, Conxa, Catalá, Miguel, Delgado, Elias, Franch, Josep, Gaztambide, Sonia, Girbés, Juan, Gomis, Ramon, Gutiérrez, Galder, López‐Alba, Alfonso, Martínez‐Larrad, Maria, Menéndez, Edelmiro, Mora‐Peces, Inmaculada, Ortega, Emilio, Pascual‐Manich, Gemma, Serrano‐Rios, Manuel, Urrutia, Ines, Vázquez, Jose Antonio, Vendrell, Joan, Soriguer, Federico, Rojo‐Martínez, Gemma

“…Objective The aim of this study was to examine possible associations between ambient temperature and obesity in the Spanish population using an ecological…”
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Low Physical Activity and Its Association with Diabetes and Other Cardiovascular Risk Factors: A Nationwide, Population-Based Study by Brugnara, Laura, Murillo, Serafín, Novials, Anna, Rojo-Martínez, Gemma, Soriguer, Federico, Goday, Albert, Calle-Pascual, Alfonso, Castaño, Luis, Gaztambide, Sonia, Valdés, Sergio, Franch, Josep, Castell, Conxa, Vendrell, Joan, Casamitjana, Roser, Bosch-Comas, Anna, Bordiú, Elena, Carmena, Rafael, Catalá, Miguel, Delgado, Elias, Girbés, Juan, López-Alba, Alfonso, Martínez-Larrad, Maria Teresa, Menéndez, Edelmiro, Mora-Peces, Inmaculada, Pascual-Manich, Gemma, Serrano-Ríos, Manuel, Gomis, Ramon, Ortega, Emilio

“…Low physical activity (PA), or sedentary lifestyle, is associated with the development of several chronic diseases. We aimed to investigate current prevalence…”
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Cerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice by del Valle, Jaume, Duran-Vilaregut, Joaquim, Manich, Gemma, Pallàs, Mercè, Camins, Antoni, Vilaplana, Jordi, Pelegrí, Carme

“…Cerebrovascular dysfunction and β-amyloid peptide deposition on the walls of cerebral blood vessels might be an early event in the development of Alzheimer's…”
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Time‐course of blood–brain barrier disruption in senescence‐accelerated mouse prone 8 (SAMP8) mice by Valle, Jaume, Duran‐Vilaregut, Joaquim, Manich, Gemma, Camins, Antoni, Pallàs, Mercè, Vilaplana, Jordi, Pelegrí, Carme

“…Senescence of the cerebrovascular system and an abnormal function of the blood–brain barrier have been related with Alzheimer's disease. We studied here the…”
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Systemic administration of 3-nitropropionic acid points out a different role for active caspase-3 in neurons and astrocytes by Duran-Vilaregut, Joaquim, del Valle, Jaume, Manich, Gemma, Junyent, Fèlix, Camins, Antoni, Pallàs, Mercè, Pelegrí, Carme, Vilaplana, Jordi

“…The intraperitoneal administration of 3-nitropropionic acid, which is commonly used to induce toxicity models of Huntington's disease in experimental animals,…”
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Role of the CD200-CD200R Axis During Homeostasis and Neuroinflammation by Manich, Gemma, Recasens, Mireia, Valente, Tony, Almolda, Beatriz, González, Berta, Castellano, Bernardo

“…•Microglial activation is regulated by neurons, through the CD200-CD200R axis.•Effects of CD200-CD200R are different under homeostatic or inflammatory…”
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Trafficking of Gold Nanoparticles Coated with the 8D3 Anti-Transferrin Receptor Antibody at the Mouse Blood–Brain Barrier by Cabezón, Itsaso, Manich, Gemma, Martín-Venegas, Raquel, Camins, Antoni, Pelegrí, Carme, Vilaplana, Jordi

“…Receptor-mediated transcytosis has been widely studied as a possible strategy to transport neurotherapeutics across the blood−brain barrier (BBB). Monoclonal…”
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Evidence for the involvement of TRPV2 channels in the modulation of vascular tone in the mouse aorta by Perálvarez-Marín, Alex, Solé, Montse, Serrano, Judith, Taddeucci, Alice, Pérez, Belén, Penas, Clara, Manich, Gemma, Jiménez, Marcel, D'Ocon, Pilar, Jiménez-Altayó, Francesc

“…Transient receptor potential vanilloid 2 (TRPV2) channels are expressed in both smooth muscle and endothelial cells and participate in vascular…”
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A strocytes and neurons produce distinct types of polyglucosan bodies in L afora disease by Augé, Elisabet, Pelegrí, Carme, Manich, Gemma, Cabezón, Itsaso, Guinovart, Joan J., Duran, Jordi, Vilaplana, Jordi

“…Abstract Lafora disease (LD), the most devastating adolescence‐onset epilepsy, is caused by mutations in the EPM2A or EPM2B genes, which encode the proteins…”
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Roadmap for Postnatal Brain Maturation: Changes in Gray and White Matter Composition during Development Measured by Fourier Transformed Infrared Microspectroscopy by Peris, Marta, Benseny-Cases, Núria, Manich, Gemma, Zerpa, Oriana, Almolda, Beatriz, Perálvarez-Marín, Àlex, González, Berta, Castellano, Bernardo

“…Key events in postnatal brain development, such as neuronal migration, synaptogenesis, and myelination, shape the adult brain. These events are reflected in…”
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Early amyloid accumulation in the hippocampus of SAMP8 mice by Del Valle, Jaume, Duran-Vilaregut, Joaquim, Manich, Gemma, Casadesús, Gemma, Smith, Mark A, Camins, Antoni, Pallàs, Mercè, Pelegrí, Carme, Vilaplana, Jordi

“…Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. To date, however, there are no non-genetically manipulated…”
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Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood–brain barrier in mice by Manich, Gemma, Cabezón, Itsaso, del Valle, Jaume, Duran-Vilaregut, Joaquim, Camins, Antoni, Pallàs, Mercè, Pelegrí, Carme, Vilaplana, Jordi

“…One strategy used to transport pharmacologically active substances across the blood–brain barrier (BBB) is to link the substance to a molecule capable of…”
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Characterization of amyloid-β granules in the hippocampus of SAMP8 mice by Manich, Gemma, Mercader, Clara, del Valle, Jaume, Duran-Vilaregut, Joaquim, Camins, Antoni, Pallàs, Mercè, Vilaplana, Jordi, Pelegrí, Carme

“…The senescence accelerated mouse-prone 8 (SAMP8) strain of mice is an experimental model of accelerated senescence that has also been proposed as a model of…”
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