Search Results - "Mani, Vasudevan"

Piracetam-induced neuroprotection in lipopolysaccharides-challenged EOC-20 cells and mouse brain via attenuating oxidative stress by Mani, Vasudevan

“…Abstract Therapeutically, piracetam has been used for decades as a cognitive enhancer for memory- related neuronal disorders. The present study aimed to…”
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Quetiapine Moderates Doxorubicin-Induced Cognitive Deficits: Influence of Oxidative Stress, Neuroinflammation, and Cellular Apoptosis by Mani, Vasudevan, Alshammeri, Bander Shehail

“…Chemotherapy is considered a major choice in cancer treatment. Unfortunately, several cognitive deficiencies and psychiatric complications have been reported…”
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Aripiprazole Attenuates Cognitive Impairments Induced by Lipopolysaccharide in Rats through the Regulation of Neuronal Inflammation, Oxidative Stress, and Apoptosis by Mani, Vasudevan, Alshammeri, Bander Shehail

“…: Aripiprazole (APZ), an atypical antipsychotic, is mainly prescribed for conditions such as schizophrenia and bipolar disorder, while ongoing research…”
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Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis by Behl, Tapan, Upadhyay, Tanuj, Singh, Sukhbir, Chigurupati, Sridevi, Alsubayiel, Amal M, Mani, Vasudevan, Vargas-De-La-Cruz, Celia, Uivarosan, Diana, Bustea, Cristiana, Sava, Cristian, Stoicescu, Manuela, Radu, Andrei-Flavius, Bungau, Simona Gabriela

“…Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disorder, predominantly symmetric, which causes joint inflammation, cartilage degeneration and…”
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Exploring the role of neuropeptides in depression and anxiety by Rana, Tarapati, Behl, Tapan, Sehgal, Aayush, Singh, Sukhbir, Sharma, Neelam, Abdeen, Ahmed, Ibrahim, Samah F., Mani, Vasudevan, Iqbal, Muhammad Shahid, Bhatia, Saurabh, Abdel Daim, Mohamed M., Bungau, Simona

“…Depression is one of the most prevalent forms of mental disorders and is the most common cause of disability in the Western world. Besides, the harmful effects…”
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Betahistine's Neuroprotective Actions against Lipopolysaccharide-Induced Neurotoxicity: Insights from Experimental and Computational Studies by Mani, Vasudevan, Arfeen, Minhajul

“…Histamine H receptor (H R) antagonists, such as betahistine (BHTE), have shown significant potential in treating central nervous system (CNS) disorders due to…”
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Impact of levetiracetam on cognitive impairment, neuroinflammation, oxidative stress, and neuronal apoptosis caused by lipopolysaccharides in rats by Mani, Vasudevan, Rashed Almutairi, Salem

“…Neuroinflammation is associated with the elevation of toxic proinflammatory mediators that promote neurodegeneration and subsequently affect cognition. Causes…”
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Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular Docking Study by Mani, Vasudevan, Arfeen, Minhajul, Rabbani, Syed Imam, Shariq, Ali, Amirthalingam, Palanisamy

“…Cancer chemotherapy-induced cognitive impairment (chemobrain) is a major complication that affects the prognosis of therapy. Our study evaluates the…”
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Beliefs and perception about mental health issues: a meta-synthesis by Choudhry, Fahad Riaz, Mani, Vasudevan, Ming, Long Chiau, Khan, Tahir Mehmood

“…Mental health literacy is the beliefs and knowledge about mental health issues and their remedies. Attitudes and beliefs of lay individuals about mental…”
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Synthesis and biological evaluation of heterocyclic 1,2,4-triazole scaffolds as promising pharmacological agents by Kumari, Mukesh, Tahlan, Sumit, Narasimhan, Balasubramanian, Ramasamy, Kalavathy, Lim, Siong Meng, Shah, Syed Adnan Ali, Mani, Vasudevan, Kakkar, Saloni

“…Background Triazole is an important heterocyclic moiety that occupies a unique position in heterocyclic chemistry, due to its large number of biological…”
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Benzoxazole derivatives: design, synthesis and biological evaluation by Kakkar, Saloni, Tahlan, Sumit, Lim, Siong Meng, Ramasamy, Kalavathy, Mani, Vasudevan, Shah, Syed Adnan Ali, Narasimhan, Balasubramanian

“…Background A new series of benzoxazole analogues was synthesized and checked for their in vitro antibacterial, antifungal and anticancer activities. Results…”
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Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease by Gnanasegaran, Nareshwaran, Govindasamy, Vijayendran, Mani, Vasudevan, Abu Kasim, Noor Hayaty

“…In neurodegenerative diseases, such as Alzheimer's and Parkinson's, microglial cell activation is thought to contribute to their degeneration by producing…”
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Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain by Ahmad, Aliya, Ramasamy, Kalavathy, Jaafar, Siti Murnirah, Majeed, Abu Bakar Abdul, Mani, Vasudevan

“…•Soybean and tempeh isoflavones reversed scopolamine-induced memory impairment.•Soybean and tempeh isoflavones improved brain cholinergic activities.•Soybean…”
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Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats by Mani, Vasudevan, Rabbani, Syed Imam, Shariq, Ali, Amirthalingam, Palanisamy, Arfeen, Minhajul

“…Cancer chemotherapy is known to cause cognitive defects in patients. Our study investigated the effect of piracetam (PIRA; 200 or 400 mg/kg) against…”
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Sea Horse Optimization-Deep Neural Network: A Medication Adherence Monitoring System Based on Hand Gesture Recognition by Amirthalingam, Palanisamy, Alatawi, Yasser, Chellamani, Narmatha, Shanmuganathan, Manimurugan, Ali, Mostafa A Sayed, Alqifari, Saleh Fahad, Mani, Vasudevan, Dhanasekaran, Muralikrishnan, Alqahtani, Abdulelah Saeed, Alanazi, Majed Falah, Aljabri, Ahmed

“…Medication adherence is an essential aspect of healthcare for patients and is important for achieving medical objectives. However, the lack of standard…”
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Proximate composition, lipid and elemental profiling of eight varieties of avocado (Persea americana) by Nasri, Chaimae, Halabi, Yasmina, Hajib, Ahmed, Choukri, Hasnae, Harhar, Hicham, Lee, Learn-Han, Mani, Vasudevan, Ming, Long Chiau, Goh, Khang Wen, Bouyahya, Abdelhakim, Tabyaoui, Mohamed

“…Eight Moroccan avocado varieties were analyzed for their nutritional composition and physicochemical properties. The nutritional contents of the sample were…”
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Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders by Bhatia, Saurabh, Makkar, Rashita, Behl, Tapan, Sehgal, Aayush, Singh, Sukhbir, Rachamalla, Mahesh, Mani, Vasudevan, Iqbal, Muhammad Shahid, Bungau, Simona Gabriela

“…Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of…”
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In-silico molecular design of heterocyclic benzimidazole scaffolds as prospective anticancer agents by Tahlan, Sumit, Kumar, Sanjiv, Ramasamy, Kalavathy, Lim, Siong Meng, Shah, Syed Adnan Ali, Mani, Vasudevan, Narasimhan, Balasubramanian

“…Benzimidazole is a valuable pharmacophore in the field of medicinal chemistry and exhibit wide spectrum of biological activity. Molecular docking technique is…”
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Antinociceptive and anti-inflammatory effects of Thespesia populnea bark extract by Vasudevan, Mani, Gunnam, Kumar Kishore, Parle, Milind

“…The ethanolic extract of Thespesia populnea bark (TPE) was investigated for anti-inflammatory and analgesic activity at the doses (p.o.) of 100, 200 and 400…”
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Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress by Rahim, Nur Syafiqah, Lim, Siong Meng, Mani, Vasudevan, Abdul Majeed, Abu Bakar, Ramasamy, Kalavathy

“…Context: Virgin coconut oil (VCO) has been reported to possess antioxidative, anti-inflammatory and anti-stress properties. Objective: Capitalizing on these…”
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