Search Results - "Mani, Jean‐Claude"

Intracellular distribution of viral gene products regulates a complex mechanism of cauliflower mosaic virus acquisition by its aphid vector by Drucker, Martin, Froissart, Rémy, Hébrard, Eugénie, Uzest, Marilyne, Ravallec, Marc, Espérandieu, Pascal, Mani, Jean-Claude, Pugnière, Martine, Roquet, Françoise, Fereres, Alberto, Blanc, Stéphane

“…Interactions between Cauliflower mosaic virus (CaMV) and its aphid vector are regulated by the viral protein P2, which binds to the aphid stylets, and protein…”
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Functional Specific Binding of Testosterone to Schistosoma haematobium 28-Kilodalton Glutathione S-Transferase by REMOUE, Franck, MANI, Jean-Claude, PUGNIERE, Martine, SCHACHT, Anne-Marie, CAPRON, André, RIVEAU, Gilles

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Characterization of a new intrabody directed against the N-terminal region of human p53 by COHEN, P. A, MANI, J.-C, LANE, D. P

“…Genes encoding the rearranged immunoglobulin heavy and light chain variable regions of DO-1, a monoclonal antibody directed against human p53, have been used…”
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Changes in the Dimeric State of Neuronal Nitric Oxide Synthase Affect the Kinetics of Secretagogue-Induced Insulin Response by Lajoix, Anne-Dominique, Pugnière, Martine, Roquet, Françoise, Mani, Jean-Claude, Dietz, Samuel, Linck, Nathalie, Faurie, Fleur, Ribes, Gérard, Petit, Pierre, Gross, René

“…Changes in the Dimeric State of Neuronal Nitric Oxide Synthase Affect the Kinetics of Secretagogue-Induced Insulin Response Anne-Dominique Lajoix 1 2 , Martine…”
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Systematic mapping of regions of human cardiac troponin I involved in binding to cardiac troponin C: N- and C-terminal low affinity contributing regions by Ferrières, Gaëlle, Pugnière, Martine, Mani, Jean-Claude, Villard, Sylvie, Laprade, Michel, Doutre, Patrick, Pau, Bernard, Granier, Claude

“…The Spot method of multiple peptide synthesis was used to map in a systematic manner regions of the human cardiac troponin I sequence (hcTnI) involved in…”
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Increased cathepsin D level in the serum of patients with metastatic breast carcinoma detected with a specific pro‐cathepsin D immunoassay by Brouillet, Jean‐Paul, Dufour, Franck, Lemamy, Guy, Garcia, Marcel, Schlup, Nicolas, Grenier, Jean, Mani, Jean‐Claude, Rochefort, Henri

“…BACKGROUND An increased cathepsin D (cath‐D) level in breast carcinoma cytosol has been proposed as a prognostic parameter. However, no increase had been…”
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Systematic Exploration of the Antigen Binding Activity of Synthetic Peptides Isolated from the Variable Regions of Immunoglobulins by Laune, Daniel, Molina, Franck, Ferrieres, Gaelle, Mani, Jean-Claude, Cohen, Pascale, Simon, Dominique, Bernardi, Thierry, Piechaczyk, Martine, Pau, Bernard, Granier, Claude

“…Sets of short (12 residues) cellulose-bound synthetic overlapping peptides derived from the sequences of the variable regions of the heavy and light chains of…”
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Synthetic Peptides Derived from the Variable Regions of an Anti-CD4 Monoclonal Antibody Bind to CD4 and Inhibit HIV-1 Promoter Activation in Virus-infected Cells by Monnet, Céline, Laune, Daniel, Laroche-Traineau, Jeanny, Biard-Piechaczyk, Martine, Briant, Laurence, Bès, Cédric, Pugnière, Martine, Mani, Jean-Claude, Pau, Bernard, Cerutti, Martine, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…The monoclonal antibody (mAb) ST40, specific for the immunoglobulin complementarity-determining region (CDR) 3-like loop in domain 1 of the CD4 molecule,…”
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Monoclonal Antibody 667 Recognizes the Variable Region A Motif of the Ecotropic Retrovirus CasBrE Envelope Glycoprotein and Inhibits Env Binding to the Viral Receptor by Dreja, Hanna, Gros, Laurent, Villard, Sylvie, Bachrach, Estanislao, Oates, Anna, Granier, Claude, Chardes, Thierry, Mani, Jean-Claude, Piechaczyk, Marc, Pelegrin, Mireia

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Mapping the CD4 Binding Domain of gp17, a Glycoprotein Secreted from Seminal Vesicles and Breast Carcinomas by Basmaciogullari, Stéphane, Autiero, Monica, Culerrier, Raphaël, Mani, Jean-Claude, Gaubin, Muriel, Mishal, Zohar, Guardiola, John, Granier, Claude, Piatier-Tonneau, Dominique

“…gp17, a secretory CD4-binding factor isolated from the human seminal plasma, is identical to the gross cystic disease fluid protein-15, a specific marker for…”
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Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA) by Robert, Bruno, Dorvillius, Mylène, Buchegger, Franz, Garambois, Véronique, Mani, Jean‐Claude, Pugnières, Martine, Mach, Jean‐Pierre, Pèlegrin, André

“…In an attempt to improve tumor targeting and tumor retention time of monoclonal antibodies (MAbs), we prepared biparatopic antibodies (BpAbs) having the…”
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Differential antibody reactivity and CD4 binding of the mammary tumor marker protein GCDFP‐15 from breast cyst and its counterparts from exocrine epithelia by Caputo, Emilia, Autiero, Monica, Mani, Jean‐Claude, Basmociogullari, Stéphane, Piatier‐Tonneau, Dominique, Guardiola, John

“…Analysis of biopsies from breast cancer patients demonstrated that GCDFP‐15 (gross cystic disease fluid protein‐15) is a specific immunocytochemical marker of…”
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Anti-digoxin scFv fragments expressed in bacteria and in insect cells have different antigen binding properties by Lemeulle, Corinne, Chardès, Thierry, Montavon, Céline, Chaabihi, Hassan, Mani, Jean-Claude, Pugnière, Martine, Cerutti, Martine, Devauchelle, Gérard, Pau, Bernard, Biard-Piechaczyk, Martine

“…A gene encoding a single-chain antibody fragment directed against digoxin (named 1C10 scFv) was cloned in two expression systems. For this purpose, a new…”
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High-affinity antibodies from hen's-egg yolks against human mannose-6-phosphate/insulin-like growth-factor-II receptor (M6P/IGFII-R): Characterization and potential use in clinical cancer studies by Lemamy, Guy-Joseph, Roger, Pascal, Mani, Jean-Claude, Robert, Mich le, Rochefort, Henri, Brouillet, Jean-Paul

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Interactions of the human, rat, Saccharomyces cerevisiae and Escherichia coli 3-methyladenine-DNA glycosylases with DNA containing dIMP residues by Saparbaev, M, Mani, J C, Laval, J

“…In DNA, the deamination of dAMP generates 2'-deoxy-inosine 5'-monophosphate (dIMP). Hypoxanthine (HX) residues are mutagenic since they give rise to A.T-->G.C…”
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Normal Human Serum Contains Natural Antibodies Reactive With Autologous ABO Blood Group Antigens by Spalter, Sergio H., Kaveri, Srini V., Bonnin, Emmanuelle, Mani, Jean-Claude, Cartron, Jean-Pierre, Kazatchkine, Michel D.

“…It is widely accepted that the serum of healthy individuals contains natural antibodies only against those blood group A or B antigens that are not expressed…”
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A peptide mimetic of an anti-CD4 monoclonal antibody by rational design by Casset, Florence, Roux, Florence, Mouchet, Patrick, Bes, Cedric, Chardes, Thierry, Granier, Claude, Mani, Jean-Claude, Pugnière, Martine, Laune, Daniel, Pau, Bernard, Kaczorek, Michel, Lahana, Roger, Rees, Anthony

“…The development of rational methods to design ‘continuous’ sequence mimetics of discontinuous regions of protein sequence has, to now, been only marginally…”
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Extracellular ATP and cell signalling by el-Moatassim, C, Dornand, J, Mani, J C

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Affinity of recombinant antibody and antibody fragment binding to human thyroglobulin: potential applications in gene therapy by Mani, Jean-Claude, Noel, Danièle, Marin, Mariana, Navarro-Teulon, Isabelle, Biard-Piechaczyk, Martine, Pau, Bernard, Piechaczyk, Marc

“…Recombinant antibodies and antibody fragments are currently being produced. They can be used in vitro for the structural study of antigen–antibody interactions…”
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Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain by Chenal, Alexandre, Nizard, Philippe, Forge, Vincent, Pugnière, Martine, Roy, Marie-Odile, Mani, Jean-Claude, Guillain, Florent, Gillet, Daniel

“…We investigated whether the structural and functional behaviors of two unrelated protein domains were modified when fused. The IgG-binding protein ZZ derived…”
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