Search Results - "Mani, Geeta Sai"
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Synthesis and biological evaluation of substituted N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides as tubulin polymerization inhibitors
Published in Bioorganic chemistry (01-10-2020)“…[Display omitted] •New N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides were synthesized.•The compound 12h showed potent activity against the cancer cell line…”
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Iodine-mediated C-N and N-N bond formation: a facile one-pot synthetic approach to 1,2,3-triazoles under metal-free and azide-free conditions
Published in RSC advances (28-08-2019)“…A novel strategy towards the synthesis of 1,4-disubstituted 1,2,3-triazoles via C-N and N-N bond formation has been demonstrated under transition metal-free…”
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One-Pot, Three-Component Approach to the Synthesis of 3,4,5-Trisubstituted Pyrazoles
Published in Journal of organic chemistry (01-05-2015)“…An operationally simple and high yielding protocol for the synthesis of polyfunctional pyrazoles has been developed through one-pot, three-component coupling…”
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New (3-(1 H -benzo[ d ]imidazol-2-yl))/(3-(3 H -imidazo[4,5- b ]pyridin-2-yl))-(1 H -indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates as tubulin polymerization inhibitors
Published in MedChemComm (01-02-2018)“…A series of new (3-(1 -benzo[ ]imidazol-2-yl))/(3-(3 -imidazo[4,5- ]pyridin-2-yl))-(1 -indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates were synthesized…”
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Access to Imidazo[1,2‑a]pyridines via Annulation of α‑Keto Vinyl Azides and 2‑Aminopyridines
Published in Organic letters (04-09-2015)“…A novel strategy for the synthesis of imidazo[1,2-a]pyridines via efficient catalyst/metal-free annulations of α-keto vinyl azides and 2-aminopyridines is…”
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Synthesis of (Z)-3-(arylamino)-1-(3-phenylimidazo[1,5-a]pyridin-1-yl)prop-2-en-1-ones as potential cytotoxic agents
Published in Bioorganic & medicinal chemistry letters (15-09-2020)“…[Display omitted] The new derivatives based on (Z)-3-(arylamino)-1-(3-phenylimidazo[1,5-a]pyridin-1-yl)prop-2-en-1-one scaffold was synthesized and evaluated…”
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Synthesis and biological evaluation of spiro[cyclopropane-1,3′-indolin]-2′-ones as potential anticancer agents
Published in Bioorganic & medicinal chemistry letters (15-10-2015)“…[Display omitted] Libraries of spiro[cyclopropane-1,3′-indolin]-2′-ones were synthesized and evaluated for their biological activity against five different…”
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Iodine‐Mediated Oxidative Annulation by C–C Cleavage: A Domino Synthetic Approach to Quinazolinones and Benzo[4,5]imidazo[1,2‐c]quinazolines
Published in ChemistrySelect (Weinheim) (07-04-2020)“…A facile iodine‐mediated unprecedented C–C cleavage by employing CuI has been established towards the synthesis of quinazolin‐4(3H)‐ones and…”
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Highly diastereoselective synthesis of spiro[cyclopropane-1,3′-indolin]-2′-ones via catalyst-free cyclopropanation using ethyl diazoacetate
Published in Tetrahedron (12-08-2014)“…Substituted 3-methyleneindolin-2-ones were efficiently cyclopropanated with ethyl diazoacetate to yield spiro[cyclopropane-1,3′-indolin]-2′-ones in a…”
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New (3-(1H-benzo[d]imidazol-2-yl))/(3-(3H-imidazo[4,5-b]pyridin-2-yl))-(1H-indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates as tubulin polymerization inhibitorsElectronic supplementary information (ESI) available. See DOI: 10.1039/c7md00450h
Published 21-02-2018“…A series of new (3-(1 H -benzo[ d ]imidazol-2-yl))/(3-(3 H -imidazo[4,5- b ]pyridin-2-yl))-(1 H -indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates…”
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New (3-(1H-benzo[d]imidazol-2-yl))/(3-(3H-imidazo[4,5-b]pyridin-2-yl))-(1H-indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates as tubulin polymerization inhibitors† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00450h
Published in MedChemComm (12-12-2017)“…A series of new benzimidazole-indole linked phenstatin conjugates 4–6(a–i) were synthesized and evaluated for their anticancer activity. A series of new (3-(1…”
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