Search Results - "Mangogna, Alessandro"

Uterine Immunity and Microbiota: A Shifting Paradigm by Agostinis, Chiara, Mangogna, Alessandro, Bossi, Fleur, Ricci, Giuseppe, Kishore, Uday, Bulla, Roberta

“…The female reproductive tract harbors distinct microbial communities, as in the vagina, cervical canal, uterus, and fallopian tubes. The nature of the vaginal…”
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Immunological Basis of the Endometriosis: The Complement System as a Potential Therapeutic Target by Agostinis, Chiara, Balduit, Andrea, Mangogna, Alessandro, Zito, Gabriella, Romano, Federico, Ricci, Giuseppe, Kishore, Uday, Bulla, Roberta

“…Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of functional endometrial glands and stroma outside the uterine cavity…”
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COVID-19, Pre-Eclampsia, and Complement System by Agostinis, Chiara, Mangogna, Alessandro, Balduit, Andrea, Aghamajidi, Azin, Ricci, Giuseppe, Kishore, Uday, Bulla, Roberta

“…COVID-19 is characterized by virus-induced injury leading to multi-organ failure, together with inflammatory reaction, endothelial cell (EC) injury, and…”
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Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies by Bortot, Barbara, Mangogna, Alessandro, Di Lorenzo, Giovanni, Stabile, Guglielmo, Ricci, Giuseppe, Biffi, Stefania

“…Surgical resection is the cornerstone of solid tumour treatment. Current techniques for evaluating margin statuses, such as frozen section, imprint cytology,…”
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Systematic review of the complement components as potential biomarkers of pre-eclampsia: pitfalls and opportunities by Balduit, Andrea, Agostinis, Chiara, Mangogna, Alessandro, Zito, Gabriella, Stampalija, Tamara, Ricci, Giuseppe, Bulla, Roberta

“…The complement system (C) is a crucial component of the innate immune system. An increasing body of research has progressively shed light on the pivotal role…”
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Prognostic Implications of the Complement Protein C1q in Gliomas by Mangogna, Alessandro, Belmonte, Beatrice, Agostinis, Chiara, Zacchi, Paola, Iacopino, Domenico Gerardo, Martorana, Anna, Rodolico, Vito, Bonazza, Deborah, Zanconati, Fabrizio, Kishore, Uday, Bulla, Roberta

“…The contribution of the complement system in the pathophysiology of brain cancers has been recently considered in light of its well-known involvement in…”
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The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value by Zacchi, Paola, Belmonte, Beatrice, Mangogna, Alessandro, Morello, Gaia, Scola, Letizia, Martorana, Anna, Borelli, Violetta

“…Hephaestin (HEPH) belongs to a group of exocytoplasmic ferroxidases which contribute to cellular iron homeostasis by favouring its export. Down-regulation of…”
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Mechanism of action and therapeutic use of bempedoic acid in atherosclerosis and metabolic syndrome by Biolo, Gianni, Vinci, Pierandrea, Mangogna, Alessandro, Landolfo, Matteo, Schincariol, Paolo, Fiotti, Nicola, Mearelli, Filippo, Di Girolamo, Filippo Giorgio

“…Bempedoic acid is a new cholesterol-lowering drug, which has recently received US FDA and EMA approval. This drug targets lipid and glucose metabolism as well…”
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PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis by Belmonte, Beatrice, Di Lorenzo, Giovanni, Mangogna, Alessandro, Bortot, Barbara, Bertolazzi, Giorgio, Sammataro, Selene, Merighi, Simona, Martorana, Anna, Zito, Gabriella, Romano, Federico, Giorgiutti, Anna, Bottin, Cristina, Zanconati, Fabrizio, Romano, Andrea, Ricci, Giuseppe, Biffi, Stefania

“…Endometriosis is a gynecological disease characterized by the presence of endometrial tissue in abnormal locations, leading to severe symptoms, inflammation,…”
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Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas by Mangogna, Alessandro, Agostinis, Chiara, Bonazza, Deborah, Belmonte, Beatrice, Zacchi, Paola, Zito, Gabriella, Romano, Andrea, Zanconati, Fabrizio, Ricci, Giuseppe, Kishore, Uday, Bulla, Roberta

“…C1q is the first subcomponent of the classical pathway of the complement system and belongs to the C1q/Tumor Necrosis Factor superfamily. C1q can perform a…”
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Multiple-Organ Complement Deposition on Vascular Endothelium in COVID-19 Patients by Macor, Paolo, Durigutto, Paolo, Mangogna, Alessandro, Bussani, Rossana, De Maso, Luca, D'Errico, Stefano, Zanon, Martina, Pozzi, Nicola, Meroni, Pier Luigi, Tedesco, Francesco

“…Increased levels of circulating complement activation products have been reported in COVID-19 patients, but only limited information is available on complement…”
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Anti-Spike Antibodies Present in the Milk of SARS-CoV-2 Vaccinated Mothers Are Complement-Activating by Agostinis, Chiara, Toffoli, Miriam, Balduit, Andrea, Mangogna, Alessandro, Yasmin, Hadida, Ragazzon, Chiara, Pegoraro, Silvia, Campisciano, Giuseppina, Stabile, Guglielmo, Zito, Gabriella, Kishore, Uday, Comar, Manola, Scrimin, Federica, Bulla, Roberta, Ricci, Giuseppe

“…Although only 0.8-1% of SARS-CoV-2 infections are in the 0-9 age-group, pneumonia is still the leading cause of infant mortality globally. Antibodies…”
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Zinc Oxide Exerts Anti-Inflammatory Properties on Human Placental Cells by Balduit, Andrea, Mangogna, Alessandro, Agostinis, Chiara, Zito, Gabriella, Romano, Federico, Ricci, Giuseppe, Bulla, Roberta

“…An aberrant and persistent inflammatory state at the fetal-maternal interface is considered as a key contributor in compromised pregnancies. Decidual…”
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Complement Protein C1q Binds to Hyaluronic Acid in the Malignant Pleural Mesothelioma Microenvironment and Promotes Tumor Growth by Agostinis, Chiara, Vidergar, Romana, Belmonte, Beatrice, Mangogna, Alessandro, Amadio, Leonardo, Geri, Pietro, Borelli, Violetta, Zanconati, Fabrizio, Tedesco, Francesco, Confalonieri, Marco, Tripodo, Claudio, Kishore, Uday, Bulla, Roberta

“…C1q is the first recognition subcomponent of the complement classical pathway, which acts toward the clearance of pathogens and apoptotic cells. C1q is also…”
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Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae by Belmonte, Beatrice, Mangogna, Alessandro, Gulino, Alessandro, Cancila, Valeria, Morello, Gaia, Agostinis, Chiara, Bulla, Roberta, Ricci, Giuseppe, Fraggetta, Filippo, Botto, Marina, Garred, Peter, Tedesco, Francesco

“…Pre-eclampsia is a pregnancy complication characterized by defective vascular remodeling in maternal decidua responsible for reduced blood flow leading to…”
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A likely association between low mannan-binding lectin level and brain fog onset in long COVID patients by Bulla, Roberta, Rossi, Lucrezia, Furlanis, Giovanni, Agostinis, Chiara, Toffoli, Miriam, Balduit, Andrea, Mangogna, Alessandro, Liccari, Marco, Morosini, Giorgia, Kishore, Uday, Manganotti, Paolo

“…Brain fog can be described as a constellation of new-onset neuropsychiatric sequelae in the post-acute phase of COVID-19 (long COVID). The symptoms include…”
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Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma by Balduit, Andrea, Vidergar, Romana, Zacchi, Paola, Mangogna, Alessandro, Agostinis, Chiara, Grandolfo, Micaela, Bottin, Cristina, Salton, Francesco, Confalonieri, Paola, Rocca, Andrea, Zanconati, Fabrizio, Confalonieri, Marco, Kishore, Uday, Ghebrehiwet, Berhane, Bulla, Roberta

“…Complement component C1q can act as a pro-tumorigenic factor in the tumor microenvironment (TME). The TME in malignant pleural mesothelioma (MPM) is rich in…”
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High charge of cerebroid nests in nodular melanomas predicts tumor aggressiveness and high mutational tumoral burden: a pilot study by Caramaschi, Stefania, Mangogna, Alessandro, Bertoni, Laura, Manfredini, Marco, Farnetani, Francesca, Parente, Paola, Attino, Vito, Cazzato, Gerardo, Salviato, Tiziana, Pellacani, Giovanni, Reggiani Bonetti, Luca

“…Even today, melanoma is a highly aggressive neoplasm with a high mortality rate. The nodular type is very aggressive and has cerebroid nests of melanocytes…”
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Proangiogenic properties of complement protein C1q can contribute to endometriosis by Agostinis, Chiara, Toffoli, Miriam, Zito, Gabriella, Balduit, Andrea, Pegoraro, Silvia, Spazzapan, Mariagiulia, Pascolo, Lorella, Romano, Federico, Di Lorenzo, Giovanni, Mangogna, Alessandro, Santin, Aurora, Spedicati, Beatrice, Valencic, Erica, Girotto, Giorgia, Ricci, Giuseppe, Kishore, Uday, Bulla, Roberta

“…Endometriosis (EM) is defined as the engraftment and proliferation of functional endometrial-like tissue outside the uterine cavity, leading to a chronic…”
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Pancreatic ductal adenocarcinoma in colonic wall: metastatic disease or cancerized pancreatic ectopic tissue? by Gallo, Graziana, Mangogna, Alessandro, Manco, Gianrocco, Caramaschi, Stefania, Salviato, Tiziana

“…We describe two unusual cases of cancerized ectopic pancreatic parenchyma within the wall of the left colon. Although the morphology of the neoplastic cells…”
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