Search Results - "Mangner, T. J"

Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction by ASANO, E, CHUGANI, D. C, MUZIK, O, BEHEN, M, JANISSE, J, ROTHERMEL, R, MANGNER, T. J, CHAKRABORTY, P. K, CHUGANI, H. T

“…To examine the relationship between autism and epilepsy in relation to structural and functional brain abnormalities in children with tuberous sclerosis…”
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Alpha-methyl-l-tryptophan PET detects epileptogenic cortex in children with intractable epilepsy by JUHASZ, C, CHUGANI, D. C, MUZIK, O, SHAH, A, ASANO, E, MANGNER, T. J, CHAKRABORTY, P. K, SOOD, S, CHUGANI, H. T

“…In children with tuberous sclerosis, the PET tracer alpha[11C]methyl-L-tryptophan (AMT) has been shown to be selectively taken up by epileptogenic tubers, thus…”
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Brain Mapping of Language and Auditory Perception in High-Functioning Autistic Adults: A PET Study by Muller, R-A, Behen, M. E, Rothermel, R. D, Chugani, D. C, Muzik, O, Mangner, T. J, Chugani, H. T

“…A study used positron emission tomography (PET) to study patterns of brain activation during auditory processing in five high-functioning adults with autism…”
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Imaging epileptogenic tubers in children with tuberous sclerosis complex using alpha-[11C]methyl-L-tryptophan positron emission tomography by Chugani, D C, Chugani, H T, Muzik, O, Shah, J R, Shah, A K, Canady, A, Mangner, T J, Chakraborty, P K

“…Several reports have indicated that cortical resection is effective in alleviating intractable epilepsy in children with tuberous sclerosis complex (TSC)…”
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Validation of Nitrogen-13-Ammonia Tracer Kinetic Model for Quantification of Myocardial Blood Flow Using PET by Muzik, Otto, Beanlands, Rob S.B, Hutchins, Gary D, Mangner, Tom J, Nguyen, Ngoc, Schwaiger, Markus

“…Positron emission tomography has been shown to provide quantitative estimates of myocardial blood flow using 13N-ammonia and 15O-water. In a validation study,…”
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Receptive and expressive language activations for sentences: a PET study by Müller, Ralph-Axel, Rothermel, Robert D, Behen, Michael E, Muzik, Otto, Mangner, Thomas J, Chugani, Harry T

“…MOST language mapping studies have focussed on activations for single-word tasks. We examined activations for verbal auditory and generation tasks using…”
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Brain Organization of Language after Early Unilateral Lesion: A PET Study by Müller, Ralph-Axel, Rothermel, Robert D., Behen, Michael E., Muzik, Otto, Mangner, Thomas J., Chakraborty, Pulak K., Chugani, Harry T.

“…Neuropsychological studies suggest that good long-term language outcome is possible following extensive early left-hemisphere damage. We explored the brain…”
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Imaging proliferation in vivo with [F-18]FLT and positron emission tomography by Shields, Anthony F, Grierson, John R, Dohmen, Bernhard M, Machulla, H.-Juergen, Stayanoff, Joseph C, Lawhorn-Crews, Jawana M, Obradovich, Joyce E, Muzik, Otto, Mangner, Thomas J

“…Positron emission tomography (PET) is now regularly used in the diagnosis and staging of cancer. These uses and its ability to monitor treatment response would…”
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Metaiodobenzylguanidine as an Index of the Adrenergic Nervous System Integrity and Function by Sisson, J.C, Wieland, D.M, Sherman, P, Mangner, T.J, Tobes, M.C, Jacques, S., Jr

“…The radiopharmaceutical, metaiodobenzylguanidine (MIBG) acts as an analog of norepinephrine (NE). Experiments in rats were carried out to determine how closely…”
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Metabolic Fate of [13N]Ammonia in Human and Canine Blood by Rosenspire, Karen C, Schwaiger, Markus, Mangner, Thomas J, Hutchins, Gary D, Sutorik, Anthony, Kuhl, David E

“…Nitrogen-13- ([13N]) ammonia is a widely used tracer for PET myocardial blood flow studies. Quantification of blood flow using tracer kinetic principles…”
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Effect of Carbon-11-Acetate Recirculation on Estimates of Myocardial Oxygen Consumption by PET by Buck, Alfred, Wolpers, H. Georg, Hutchins, Gary D, Savas, Vicky, Mangner, Thomas J, Nguyen, Ngoc, Schwaiger, Markus

“…Mono- and biexponential fitting of myocardial 11C-acetate kinetics does not account for the effect of recirculating 11C activity following intravenous…”
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Metaiodobenzylguanidine to Map Scintigraphically the Adrenergic Nervous System in Man by Sisson, J.C, Shapiro, B, Meyers, L, Mallette, S, Mangner, T.J, Wieland, D.M, Glowniak, J.V, Sherman, P, Beierwaltes, W.H

“…Metaiodobenzylguanidine (MIBG) localizes in adrenergic neurons; MIBG labeled with 123I then serves as an analog of norepinephrine, and concentrations of…”
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A high-yield and simplified procedure for the synthesis of α-[ 11C]Methyl- l-tryptophan by Chakraborty, Pulak K., Mangner, Thomas J., Chugani, Diane C., Muzik, Otto, Chugani, Harry T.

“…Alpha-[ 11C]methyl- l-tryptophan (AMT) has been synthesized by stereoselective methylation with [ 11C]methyl iodide of the lithium-enolate generated by…”
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Task-related activations in heterotopic brain malformations: a PET study by Müller, Ralph-Axel, Behen, Michael E, Muzik, Otto, Rothermel, Robert D, Downey, Ryan A, Mangner, Thomas J, Chugani, Harry T

“…POSITRON emission tomography (PET) studies have shown normal or elevated levels of glucose metabolism in neuronal heterotopia, raising the issue of potential…”
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Synthesis of (2-[ 11C]methoxy)rotenone, a marker of mitochondrial complex I activity by Charalambous, A., Mangner, T.J., Kilbourn, M.R.

“…Recent studies suggest that defects in the function of the complexes of the electron transport chain might be involved in the pathology of neurological…”
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Pheochromocytoma and the normal adrenal medulla: improved visualization with I-123 MIBG scintigraphy by Lynn, M D, Shapiro, B, Sisson, J C, Beierwaltes, W H, Meyers, L J, Ackerman, R, Mangner, T J

“…The radiopharmaceutical iodine 131 metaiodobenzylguanidine (I-131 MIBG) has been shown to locate pheochromocytomas scintigraphically with a false-negative rate…”
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Effects of Active Chronic Cocaine Use on Cardiac Sympathetic Neuronal Function Assessed by Carbon-11-Hydroxyephedrine by Melon, Pierre G, Boyd, Carol J, McVey, Stephanie, Mangner, Thomas J, Wieland, Donald M, Schwaiger, Markus

“…Cardiac toxicity of cocaine has been linked to its inhibitory effect on norepinephrine reuptake by sympathetic nerve terminals of the heart…”
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Synthesis of 2′-deoxy-2′-[ 18F]fluoro-β-D-arabinofuranosyl nucleosides, [ 18F]FAU, [ 18F]FMAU, [ 18F]FBAU and [ 18F]FIAU, as potential PET agents for imaging cellular proliferation : synthesis of [ 18F]labelled FAU, FMAU, FBAU, FIAU by Mangner, Thomas J, Klecker, Raymond W, Anderson, Lawrence, Shields, Anthony F

“…An efficient and reliable synthesis of 2′-deoxy-2′-[ 18F]fluoro-β-D-arabinofuranosyl nucleosides is presented. Overall decay-corrected radiochemical yields of…”
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Radiopharmaceutical Treatment of Malignant Pheochromocytoma by Sisson, James C, Shapiro, Brahm, Beierwaltes, William H, Glowniak, Jerry V, Nakajo, Masayuki, Mangner, Thomas J, Carey, James E, Swanson, Dennis P, Copp, Jean E, Satterlee, Winston G, Wieland, Donald M

“…Apart from relieving effects of secreted catecholamines, treatments of malignant pheochromocytoma have achieved little success. When the radiopharmaceutical,…”
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Synthesis of a [11C]methoxy derivative of alpha-dihydrotetrabenazine: a radioligand for studying the vesicular monoamine transporter by DaSilva, J N, Kilbourn, M R, Mangner, T J

“…The synthesis of [11C]TBZOMe, a [11C]methoxy derivative at the 2-hydroxy position of alpha-dihydrotetrabenazine, was carried out by an O-[11C]methylation…”
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