Search Results - "Mangili, O C"

Morphological and biochemical evidence of blood vessel damage and fibrinogenolysis triggered by brown spider venom by Zanetti, V C, da Silveira, R B, Dreyfuss, J L, Haoach, J, Mangili, O C, Veiga, S S, Gremski, W

“…The venom of the brown spider is remarkable because it causes dermonecrotic injury, hemorrhagic problems, hemolysis, platelet aggregation and renal failure…”
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Detection and characterization of metalloproteinases with gelatinolytic, fibronectinolytic and fibrinogenolytic activities in Brown spider ( Loxosceles intermedia) venom by Feitosa, Loara, Gremski, Waldemiro, Veiga, Silvio S, Elias, M.Carolina Q.B, Graner, Edgard, Mangili, Oldemir C, Brentani, Ricardo R

“…By studying Loxosceles intermedia (Brown spider) venom we were able to detect a proteolytic action on fibronectin and fibrinogen but an inability to degrade…”
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Extracellular matrix molecules as targets for brown spider venom toxins by Veiga, S S, Zanetti, V C, Braz, A, Mangili, O C, Gremski, W

“…Loxoscelism, the term used to describe lesions and clinical manifestations induced by brown spider's venom (Loxosceles genus), has attracted much attention…”
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Identification of high molecular weight serine-proteases in Loxosceles intermedia (brown spider) venom by Veiga, Silvio S., da Silveira, Rafael B., Dreyfuss, Juliana L., Haoach, Juliana, Pereira, Aline M., Mangili, Oldemir C., Gremski, Waldemiro

“…High molecular weight serine-proteases have been identified in Loxosceles intermedia (brown spider) venom. The mechanism by which Loxosceles spp venoms cause…”
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Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity by Kusma, J., Chaim, O.M., Wille, A.C.M., Ferrer, V.P., Sade, Y.B., Donatti, L., Gremski, W., Mangili, O.C., Veiga, S.S.

“…Bites from brown spiders ( Loxosceles genus) have clinical manifestations including skin necrosis with gravitational spreading, and systemic involvement that…”
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Brown spider dermonecrotic toxin directly induces nephrotoxicity by Chaim, Olga Meiri, Sade, Youssef Bacila, da Silveira, Rafael Bertoni, Toma, Leny, Kalapothakis, Evanguedes, Chávez-Olórtegui, Carlos, Mangili, Oldemir Carlos, Gremski, Waldemiro, von Dietrich, Carl Peter, Nader, Helena B., Sanches Veiga, Silvio

“…Brown spider ( Loxosceles genus) venom can induce dermonecrotic lesions at the bite site and systemic manifestations including fever, vomiting, convulsions,…”
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Structural and ultrastructural description of the venom gland of Loxosceles intermedia (brown spider) by dos Santos, Vera Lúcia P., Franco, Celia Regina C., Viggiano, Renata Lia Lana, da Silveira, Rafael Bertoni, Cantão, Maurı́cio P., Mangili, Oldemir C., Veiga, Silvio S., Gremski, Waldemiro

“…The brown spider, genus Loxosceles, is becoming of great medical importance, with envenomation (Loxoscelism) occurring throughout the world. The biological…”
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Oligosaccharide residues of Loxosceles intermedia (brown spider) venom proteins: dependence on glycosylation for dermonecrotic activity by Veiga, Silvio S., Gremski, Waldemiro, dos Santos, Vera Lúcia P., Feitosa, Loara, Mangili, Oldemir C., Nader, Helena B., Dietrich, Carl P., Brentani, Ricardo R.

“…Loxosceles spp. (brown spider) envenomation has been reported to provoke dermonecrosis and haemorrhage at the bite site (a hallmark of accidents) and, to a…”
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ELISA for the detection of venom antigens in experimental and clinical envenoming by Loxosceles intermedia spiders by Chávez-Olórtegui, Carlos, Zanetti, Vera C, Ferreira, Ana P, Minozzo, João C, Mangili, Oldemir C, Gubert, Ida C

“…Enzyme linked immunosorbent assays (ELISA) were developed to detect antigens from Loxosceles intermedia spider venom. Hyperimmune horse anti- Loxosceles…”
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Identification and molecular cloning of insecticidal toxins from the venom of the brown spider Loxosceles intermedia by de Castro, Cibele Soares, Silvestre, Flávia Galindo, Araújo, Simone Costa, Yazbeck, Gabriel de Menezes, Mangili, Oldemir C, Cruz, Ivan, Chávez-Olórtegui, Carlos, Kalapothakis, Evanguedes

“…The venom of Loxosceles intermedia was investigated for the presence of insecticidal toxins active against Spodoptera frugiperda (Lepdoptera: Noctuidade), an…”
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Identification of proteases in the extract of venom glands from brown spiders by da Silveira, Rafael B., dos Santos Filho, José F., Mangili, Oldemir C., Veiga, Silvio S., Gremski, Waldemiro, Nader, Helena B., von Dietrich, Carl P.

“…In the present investigation, in order to dispute the rational criticism against the presence of proteolytic enzymes in the electrostimulated venom obtained…”
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Molecular cloning, expression and immunological properties of LiD1, a protein from the dermonecrotic family of Loxosceles intermedia spider venom by Kalapothakis, Evanguedes, Araujo, Simone Costa, de Castro, Cibele Soares, Mendes, Thais Melo, Gomez, Marcus Vinı́cius, Mangili, Oldemir C, Gubert, Ida C, Chávez-Olórtegui, Carlos

“…The present report describes the identification and molecular characterization of LiD1, a protein expressed in the venom gland of the brown spider Loxosceles…”
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Production of monoclonal antibodies capable of neutralizing dermonecrotic activity of Loxosceles intermedia spider venom and their use in a specific immunometric assay by Alvarenga, Larissa M, Martins, Maria S, Moura, Juliana F, Kalapothakis, Evanguedes, Oliveira, Júlio C, Mangili, Oldemir C, Granier, Claude, Chávez-Olórtegui, Carlos

“…We have produced 13 mAbs for Loxosceles intermedia crude venom. Twelve were reactive against proteins of 32–35 kDa and one of these Li mAb(7) showed high…”
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Protection against dermonecrotic and lethal activities of Loxosceles intermedia spider venom by immunization with a fused recombinant protein by Araujo, Simone C, Castanheira, Paula, Alvarenga, Lanssa M, Mangili, Oldemir C, Kalapothakis, Evanguedes, Chávez-Olórtegui, Carlos

“…We report the use of a recombinant Loxosceles intermedia spider protein in the form of a fusion protein as an antigen for immunization in rabbits and mice. The…”
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Isolation and identification of Clostridium perfringens in the venom and fangs of Loxosceles intermedia (brown spider): enhancement of the dermonecrotic lesion in loxoscelism by Monteiro, Cristina Leise B., Rubel, Rosália, Cogo, Laura Lúcia, Mangili, Oldemir C., Gremski, Waldemiro, Veiga, Silvio S.

“…Loxoscelism or the envenoming by the brown spiders ( Loxosceles genus spiders), may produce extensive dermonecrosis and hemorrhage at the bite site and,…”
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In Vivo and In Vitro Cytotoxicity of Brown Spider Venom for Blood Vessel Endothelial Cells by Veiga, Silvio S, Zanetti, Vera C, Franco, Celia R.C, Trindade, Edvaldo S, Porcionatto, Marimelia A, Mangili, Oldemir C, Gremski, Waldemiro, Dietrich, Carl P, Nader, Helena B

“…The effect of brown spider ( Loxosceles intermedia) venom on endothelial cells was investigated in vivo and in vitro. Morphological and ultrastructural…”
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Effect of brown spider venom on basement membrane structures by Veiga, S S, Feitosa, L, dos Santos, V L, de Souza, G A, Ribeiro, A S, Mangili, O C, Porcionatto, M A, Nader, H B, Dietrich, C P, Brentani, R R, Gremski, W

“…Loxoscelism or necrotic arachnidism are terms used to describe lesions and reactions induced by bites (envenomation) from spiders of the genus Loxosceles…”
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Effect of temperature on proximal tubular acidification by Rubio, C R, Mangili, O C, de Mello, G B, Malnic, G

“…The effect of temperature on proximal tubular acidification was studied in isolated rat kidney, perfused with 20 mM phosphate Ringer's containing 7.5 g/100 ml…”
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Molecular cloning and functional characterization of two isoforms of dermonecrotic toxin from Loxosceles intermedia (Brown spider) venom gland by Bertoni da Silveira, Rafael, Pigozzo, Romine Bachmann, Chaim, Olga Meiri, Appel, Marcia Helena, Dreyfuss, Juliana Luporini, Toma, Leny, Mangili, Oldemir Carlos, Gremski, Waldemiro, Dietrich, Carl Peter, Nader, Helena B., Veiga, Silvio Sanches

“…Brown spider (Genus Loxosceles) bites are normally associated with necrotic skin degeneration, gravitational spreading, massive inflammatory response at…”
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Hyaluronidases in Loxosceles intermedia (Brown spider) venom are endo- β-N-acetyl- d-hexosaminidases hydrolases by da Silveira, Rafael Bertoni, Chaim, Olga Meiri, Mangili, Oldemir Carlos, Gremski, Waldemiro, Dietrich, Carl Peter, Nader, Helena B., Veiga, Silvio Sanches

“…In studying Loxosceles venom, we detected degradation of purified hyaluronic acid (HA) and hydrolysis of purified chondroitin sulphate (CS) while neither…”
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