Search Results - "Mangieri, Leandra R"

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  1. 1

    Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses by Xu, Yuanzhong, Lu, Yungang, Cassidy, Ryan M., Mangieri, Leandra R., Zhu, Canjun, Huang, Xugen, Jiang, Zhiying, Justice, Nicholas J., Xu, Yong, Arenkiel, Benjamin R., Tong, Qingchun

    Published in Nature communications (01-08-2019)
    “…Feeding is known to be profoundly affected by stress-related emotional states and eating disorders are comorbid with psychiatric symptoms and altered emotional…”
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    Journal Article
  2. 2

    GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding by Wu, Zhaofei, Kim, Eun Ran, Sun, Hao, Xu, Yuanzhong, Mangieri, Leandra R, Li, De-Pei, Pan, Hui-Lin, Xu, Yong, Arenkiel, Benjamin R, Tong, Qingchun

    Published in The Journal of neuroscience (25-02-2015)
    “…Lesions of the lateral hypothalamus (LH) cause hypophagia. However, activation of glutamatergic neurons in LH inhibits feeding. These results suggest a…”
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  3. 3

    A neural basis for antagonistic control of feeding and compulsive behaviors by Mangieri, Leandra R., Lu, Yungang, Xu, Yuanzhong, Cassidy, Ryan M., Xu, Yong, Arenkiel, Benjamin R., Tong, Qingchun

    Published in Nature communications (04-01-2018)
    “…Abnormal feeding often co-exists with compulsive behaviors, but the underlying neural basis remains unknown. Excessive self-grooming in rodents is associated…”
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  4. 4

    ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease by Mangieri, Leandra R, Mader, Burton J, Thomas, Cailin E, Taylor, Charles A, Luker, Austin M, Tse, Tonia E, Huisingh, Carrie, Shacka, John J

    Published in PloS one (01-04-2014)
    “…ATP6V0C is the bafilomycin A1-binding subunit of vacuolar ATPase, an enzyme complex that critically regulates vesicular acidification. We and others have shown…”
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    Journal Article
  5. 5

    Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death by Mader, Burton J, Pivtoraiko, Violetta N, Flippo, Hilary M, Klocke, Barbara J, Roth, Kevin A, Mangieri, Leandra R, Shacka, John J

    Published in ACS chemical neuroscience (19-12-2012)
    “…Rotenone, which selectively inhibits mitochondrial complex I, induces oxidative stress, α-synuclein accumulation, and dopaminergic neuron death, principal…”
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  6. 6

    A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues by Cassidy, Ryan M, Lu, Yungang, Jere, Madhavi, Tian, Jin-Bin, Xu, Yuanzhong, Mangieri, Leandra R, Felix-Okoroji, Blessing, Selever, Jennifer, Xu, Yong, Arenkiel, Benjamin R, Tong, Qingchun

    Published in Science advances (01-03-2019)
    “…Animals must consider competing information before deciding to eat: internal signals indicating the desirability of food and external signals indicating the…”
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  7. 7

    MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration by Harms, Ashley S, Cao, Shuwen, Rowse, Amber L, Thome, Aaron D, Li, Xinru, Mangieri, Leandra R, Cron, Randy Q, Shacka, John J, Raman, Chander, Standaert, David G

    Published in The Journal of neuroscience (05-06-2013)
    “…Accumulation of α-synuclein (α-syn) in the brain is a core feature of Parkinson disease (PD) and leads to microglial activation, production of inflammatory…”
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  8. 8

    Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia by Kim, Eun Ran, Wu, Zhaofei, Sun, Hao, Xu, Yuanzhong, Mangieri, Leandra R, Xu, Yong, Tong, Qingchun

    Published in The Journal of neuroscience (22-07-2015)
    “…The hypothalamus is critical for feeding and body weight regulation. Prevailing studies focus on hypothalamic neurons that are defined by selectively…”
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  9. 9

    Red blood cell β-adrenergic receptors contribute to diet-induced energy expenditure by increasing O2 supply by Kim, Eun Ran, Fan, Shengjie, Akhmedov, Dmitry, Sun, Kaiqi, Lim, Hoyong, O'Brien, William, Xu, Yuanzhong, Mangieri, Leandra R, Zhu, Yaming, Lee, Cheng-Chi, Chung, Yeonseok, Xia, Yang, Xu, Yong, Li, Feng, Sun, Kai, Berdeaux, Rebecca, Tong, Qingchun

    Published in JCI insight (20-07-2017)
    “…Diet-induced obesity (DIO) represents the major cause for the current obesity epidemic, but the mechanism underlying DIO is unclear. β-Adrenergic receptors…”
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    Journal Article
  10. 10

    Defensive Behaviors Driven by a Hypothalamic-Ventral Midbrain Circuit by Mangieri, Leandra R, Jiang, Zhiying, Lu, Yungang, Xu, Yuanzhong, Cassidy, Ryan M, Justice, Nicholas, Xu, Yong, Arenkiel, Benjamin R, Tong, Qingchun

    Published in eNeuro (01-07-2019)
    “…The paraventricular hypothalamus (PVH) regulates stress, feeding behaviors and other homeostatic processes, but whether PVH also drives defensive states…”
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    Journal Article
  11. 11

    VMAT2-Mediated Neurotransmission from Midbrain Leptin Receptor Neurons in Feeding Regulation by Xu, Yuanzhong, Lu, Yungang, Xu, Pingwen, Mangieri, Leandra R, Isingrini, Elsa, Xu, Yong, Giros, Bruno, Tong, Qingchun

    Published in eNeuro (01-05-2017)
    “…Leptin receptors (LepRs) expressed in the midbrain contribute to the action of leptin on feeding regulation. The midbrain neurons release a variety of…”
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  12. 12

    ATP6V0C Knockdown in Neuroblastoma Cells Alters Autophagy-Lysosome Pathway Function and Metabolism of Proteins that Accumulate in Neurodegenerative Disease: e93257 by Mangieri, Leandra R, Mader, Burton J, Thomas, Cailin E, Taylor, Charles A, Luker, Austin M, Tse, Tonia E, Huisingh, Carrie, Shacka, John J

    Published in PloS one (01-04-2014)
    “…ATP6V0C is the bafilomycin A1-binding subunit of vacuolar ATPase, an enzyme complex that critically regulates vesicular acidification. We and others have shown…”
    Get full text
    Journal Article