Search Results - "Mangalampalli, Sravani"

SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Solid Tumors by Gonzalez-Junca, Alba, Liu, Frances D, Nagaraja, Archana S, Mullenix, Alyssa, Lee, Chen-Ting, Gordley, Russell M, Frimannsson, Daniel O, Maller, Ori, Garrison, Brian S, Iyer, Dharini, Benabbas, Anissa, Truong, Tiffany A, Quach, Allison, Tian, Mengxi, Martinez, Rowena, Savur, Rishi, Perry-McNamara, Alyssa, Nguyen, Denny, Almudhfar, Niran, Blanco, Carmina, Huynh, Christina, Nand, Asish, Lay, Yu-An E, Magal, Ashita, Mangalampalli, Sravani, Lee, Philip J, Lu, Timothy K, Lee, Gary

“…Advanced peritoneal carcinomatosis including high-grade ovarian cancer has poor prognoses and a poor response rate to current checkpoint inhibitor…”
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Abstract 4246: SENTI-101, a novel genetically modified allogeneic cell product expressing IL12 and IL21, elicits a tumor-localized, robust, and multimodal immune response in preclinical models of solid tumors by Gonzalez, Alba, Liu, Frances D., Nagaraja, Archana, Mullenix, Alyssa, Gordley, Russell M., Frimannsson, Daniel O., Benabbas, Anissa, Lee, Chen-Ting, Truong, Tiffany A., Quach, Allison, Tian, Mengxi, Martinez, Rowena, Savur, Rishi, Perry-McNamara, Alyssa, Wang, Don-Hong, Maller, Ori, Iyer, Dharini, Magal, Ashita, Mangalampalli, Sravani, Huynh, Christina J., Blanco, Carmina C., Lin, Jack T., Garrison, Brian S., Lee, Philip, Lu, Timothy K., Lee, Gary

“…Abstract While immunotherapies based on single recombinant cytokines such as IL12 and IL21 have shown great promise in preclinical models of solid tumors,…”
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