Search Results - "Manfra, Michele"

Stereoselective Synthesis of Selenium-Containing Glycoconjugates via the Mitsunobu Reaction by Serpico, Luigia, De Nisco, Mauro, Cermola, Flavio, Manfra, Michele, Pedatella, Silvana

“…A simple and efficient route for the synthesis of new glycoconjugates has been developed. The approach acts as a model for a mini-library of compounds with a…”
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Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential by Miranda, Maria Rosaria, Vestuto, Vincenzo, Amodio, Giuseppina, Manfra, Michele, Pepe, Giacomo, Campiglia, Pietro

“…, known as goji berry or wolfberry, is a fruit long associated with health benefits, showing a plethora of effects ranging from antioxidant, anticancer,…”
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Different agronomic and fertilization systems affect polyphenolic profile, antioxidant capacity and mineral composition of lettuce by Sofo, Adriano, Lundegårdh, Bengt, Mårtensson, Anna, Manfra, Michele, Pepe, Giacomo, Sommella, Eduardo, De Nisco, Mauro, Tenore, Gian Carlo, Campiglia, Pietro, Scopa, Antonio

“…[Display omitted] •Green lettuce was cultivated both organically and conventionally.•Changes in the levels of plant phenols and mineral content were…”
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Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challenges to Improve Sustainability in the Development of Therapeutic Peptides by Vivenzio, Giovanni, Scala, Maria Carmina, Marino, Pasquale, Manfra, Michele, Campiglia, Pietro, Sala, Marina

“…In recent years, peptides have gained more success as therapeutic compounds. Nowadays, the preferred method to obtain peptides is solid-phase peptide synthesis…”
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Potential Role of Natural Antioxidant Products in Oncological Diseases by Marino, Pasquale, Pepe, Giacomo, Basilicata, Manuela Giovanna, Vestuto, Vincenzo, Marzocco, Stefania, Autore, Giuseppina, Procino, Alfredo, Gomez-Monterrey, Isabel Maria, Manfra, Michele, Campiglia, Pietro

“…Nutrition has a significant effect and a crucial role in disease prevention. Low consumption of fruit and vegetables and a sedentary lifestyle are closely…”
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The Ion Channels Involved in Oxidative Stress-Related Gastrointestinal Diseases by Miranda, Maria Rosaria, Vestuto, Vincenzo, Moltedo, Ornella, Manfra, Michele, Campiglia, Pietro, Pepe, Giacomo

“…The pathogenesis of various gastrointestinal (GI) disorders, including gastritis, ulcers, inflammatory bowel disease (IBD) and cancer, can be linked to…”
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Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages by Pepe, Giacomo, Sommella, Eduardo, Cianciarulo, Donato, Ostacolo, Carmine, Manfra, Michele, Di Sarno, Veronica, Musella, Simona, Russo, Mariateresa, Messore, Antonella, Parrino, Barbara, Bertamino, Alessia, Autore, Giuseppina, Marzocco, Stefania, Campiglia, Pietro

“…fruits are often employed as ingredients for functional drinks. Among , the variety, "Lempso", a typical hybrid of the Calabria region (Southern Italy), has…”
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Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress by Miranda, Maria Rosaria, Basilicata, Manuela Giovanna, Vestuto, Vincenzo, Aquino, Giovanna, Marino, Pasquale, Salviati, Emanuela, Ciaglia, Tania, Domínguez-Rodríguez, Gloria, Moltedo, Ornella, Campiglia, Pietro, Pepe, Giacomo, Manfra, Michele

“…, commonly recognized as goji berry or wolfberry, is highly appreciated not only for its organoleptic and nutritional properties but also as an important…”
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Berry morphology and composition in irrigated and non-irrigated grapevine (Vitis vinifera L.) by Sofo, Adriano, Nuzzo, Vitale, Tataranni, Giuseppe, Manfra, Michele, De Nisco, Mauro, Scopa, Antonio

“…The present study was carried out in a 5-year-old vineyard (Vitis vinifera L., cv. Aglianico) located in Southern Italy. Half of the plants (IRR) were fully…”
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Polyphenolic pattern and in vitro cardioprotective properties of typical red wines from vineyards cultivated in Scafati (Salerno, Italy) by Tenore, Gian Carlo, Manfra, Michele, Stiuso, Paola, Coppola, Luigi, Russo, Mariateresa, Ritieni, Alberto, Campiglia, Pietro

“…► Lyophilised Aglianico wine (lioAW) was tested on H9C2 cardiomyocytes. ► A good radical scavenging activity at a maximum lioAW dose of 0.03μg was detected. ►…”
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Citrus sinensis and Vitis vinifera Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies by Pepe, Giacomo, Salviati, Emanuela, Rapa, Shara Francesca, Ostacolo, Carmine, Cascioferro, Stella, Manfra, Michele, Autore, Giuseppina, Marzocco, Stefania, Campiglia, Pietro

“…The interest towards nutraceuticals able to counteract drug side effects is continuously growing in current chemotherapeutic protocols. In the present study,…”
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UHPLC profiling and effects on LPS-stimulated J774A.1 macrophages of flavonoids from bergamot (Citrus bergamia) juice, an underestimated waste product with high anti-inflammatory potential by Sommella, Eduardo, Pepe, Giacomo, Pagano, Francesco, Tenore, Gian Carlo, Marzocco, Stefania, Manfra, Michele, Calabrese, Giorgio, Aquino, Rita Patrizia, Campiglia, Pietro

“…Despite its high content of flavonoids, bergamot (Citrus bergamia) juice, is considered a waste product of the essential oil industry. In the present…”
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N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach by De Nisco, Mauro, Di Maio, Antonio, Manfra, Michele, Ostacolo, Carmine, Bertamino, Alessia, Campiglia, Pietro, Gomez-Monterrey, Isabel M., Pedatella, Silvana

“…The selective N-4 alkylation of cytosine plays a critical role in the synthesis of biologically active molecules. This work focuses on the development of…”
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Modification of Lipid Profile in Commercial Cow Milk Samples before and after Their Expiration Date: Evaluation of Storage Crucial Parameters and Possible Environmentally Friendly Disposal Alternatives by Pepe, Giacomo, Campiglia, Pietro, Vitale, Andrea, Ostacolo, Carmine, Mastrocinque, Raffaella, Manfra, Michele, Tenore, Gian Carlo, Basilicata, Manuela Giovanna, Sommella, Eduardo, Chieppa, M.

“…Milk waste is considered a highly polluting material and its disposal is an economic and environmental problem for the dairy sector. Despite this, it can be…”
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An NMR Study of the Bortezomib Degradation under Clinical Use Conditions by Bolognese, Adele, Esposito, Anna, Manfra, Michele, Catalano, Lucio, Petruzziello, Fara, Martorelli, Maria Carmen, Pagliuca, Raffaella, Mazzarelli, Vittoria, Ottiero, Maria, Scalfaro, Melania, Rotoli, Bruno

“…The (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl-boronic acid, bortezomib (BTZ), which binds the 20S proteasome subunit and causes…”
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Peptidome profiles and bioactivity elucidation of buffalo-milk dairy products after gastrointestinal digestion by Basilicata, Manuela Giovanna, Pepe, Giacomo, Sommella, Eduardo, Ostacolo, Carmine, Manfra, Michele, Sosto, Gennaro, Pagano, Giuseppe, Novellino, Ettore, Campiglia, Pietro

“…Buffalo milk is highly appreciated for its nutritive properties and highly employed in dairy products, despite this the release of bioactive peptides has not…”
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Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new l-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors by Pedatella, Silvana, Cerchia, Carmen, Manfra, Michele, Cioce, Anna, Bolognese, Adele, Lavecchia, Antonio

“…A series of l-lysine-conjugated pyridophenoxazinones 2–5 and 2′-5′ were designed and synthesized for developing compounds with multimodal anticancer…”
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Chemical profiling of bioactive constituents in hop cones and pellets extracts by online comprehensive two‐dimensional liquid chromatography with tandem mass spectrometry and direct infusion Fourier transform ion cyclotron resonance mass spectrometry by Sommella, Eduardo, Pagano, Francesco, Salviati, Emanuela, Chieppa, Marcello, Bertamino, Alessia, Manfra, Michele, Sala, Marina, Novellino, Ettore, Campiglia, Pietro

“…Humulus lupulus L. (hop) is highly interesting from a nutraceutical perspective. The hop phytocomplex contains a wide range of bioactive metabolites, and its…”
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Online comprehensive hydrophilic interaction chromatography × reversed phase liquid chromatography coupled to mass spectrometry for in depth peptidomic profile of microalgae gastro-intestinal digests by Sommella, Eduardo, Salviati, Emanuela, Merciai, Fabrizio, Manfra, Michele, Bertamino, Alessia, Gasparrini, Francesco, Novellino, Ettore, Campiglia, Pietro

“…•A HILIC × RP-MS approach with trap-columns was developed for microalgae peptidomics.•Custom-made C18 trapping columns packed with 1.9 μm monodisperse FPP were…”
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Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity by Musella, Simona, Carotenuto, Lidia, Iraci, Nunzio, Baroli, Giulia, Ciaglia, Tania, Nappi, Piera, Basilicata, Manuela Giovanna, Salviati, Emanuela, Barrese, Vincenzo, Vestuto, Vincenzo, Pignataro, Giuseppe, Pepe, Giacomo, Sommella, Eduardo, Di Sarno, Veronica, Manfra, Michele, Campiglia, Pietro, Gomez-Monterrey, Isabel, Bertamino, Alessia, Taglialatela, Maurizio, Ostacolo, Carmine, Miceli, Francesco

“…Neuronal Kv7 channels represent important pharmacological targets for hyperexcitability disorders including epilepsy. Retigabine is the prototype Kv7 activator…”
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