Search Results - "Maneewatch, Santi"
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Cell Penetrable Humanized-VH/VHH That Inhibit RNA Dependent RNA Polymerase (NS5B) of HCV
Published in PloS one (08-11-2012)“…NS5B is pivotal RNA dependent RNA polymerase (RdRp) of HCV and NS5B function interfering halts the virus infective cycle. This work aimed to produce cell…”
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2
Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxin
Published in Journal of proteomics (06-03-2009)“…Animal derived anti-Naja. kaouthia (Thai cobra) venom is used for specific treatment of the snake bitten victims. Many recipients develop allergic reaction or…”
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3
Humanized-monoclonal antibody against heterologous Leptospira infection
Published in Protein engineering, design and selection (01-05-2009)“…Patients with leptospirosis are commonly treated with antibiotics. Jarisch–Herxheimer reaction caused by toxic bacterial substances massively released as a…”
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4
Proteome and immunome of pathogenic Leptospira spp. revealed by 2DE and 2DE-immunoblotting with immune serum
Published in Asian Pacific journal of allergy and immunology (01-03-2007)“…In this study, proteomes of two pathogenic Leptospira spp., namely L. interrogans, serogroup Icterohaemorrhagiae, serovar Copenhageni and L. borgpetersenii,…”
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Cell penetrable humanized-VH/V(H)H that inhibit RNA dependent RNA polymerase (NS5B) of HCV
Published in PloS one (2012)“…NS5B is pivotal RNA dependent RNA polymerase (RdRp) of HCV and NS5B function interfering halts the virus infective cycle. This work aimed to produce cell…”
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6
OmpL1 DNA vaccine cross-protects against heterologous Leptospira spp. challenge
Published in Asian Pacific journal of allergy and immunology (01-03-2007)“…Available leptospirosis vaccines made up of inactivated bacteria or their membrane components elicit immunity which is serovar specific and unsatisfactory…”
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Components of pathogenic Leptospira spp. with potentials for diagnosis of human leptospirosis
Published in Asian Pacific journal of allergy and immunology (01-12-2007)“…Existing serological methods for diagnosis of leptospirosis are still unsatisfactorily due mainly to their low accuracy. In this study, serum samples of 18…”
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A VHH That Neutralizes the Zinc Metalloproteinase Activity of Botulinum Neurotoxin Type A
Published in The Journal of biological chemistry (26-03-2010)“…The current treatment of botulism is to administer animal-derived antitoxin, which frequently causes severe adverse reactions in the recipients. In this study,…”
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Human transbodies to VP40 inhibit cellular egress of Ebola virus-like particles
Published in Biochemical and biophysical research communications (14-10-2016)“…A direct acting anti-Ebola agent is needed. VP40, a conserved protein across Ebolavirus (EBOV) species has several pivotal roles in the virus life cycle…”
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10
Therapeutic epitopes of Leptospira LipL32 protein and their characteristics
Published in Protein engineering, design and selection (01-05-2014)“…Two LipL32-specific mouse monoclonal antibodies (mAbLPF1 and mAbLPF2) which neutralized Leptospira-mediated hemolysis in vitro and rescued hamsters from lethal…”
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A Human Single Chain Transbody Specific to Matrix Protein (M1) Interferes with the Replication of Influenza A Virus
Published in Bioconjugate chemistry (21-07-2010)“…A cell penetrating format of human single chain antibody (HuScFv) specific to matrix protein (M1) of influenza A virus was produced by molecular linking of the…”
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Human monoclonal ScFv specific to NS1 protein inhibits replication of influenza viruses across types and subtypes
Published in Antiviral research (01-10-2013)“…•NS1 specific human ScFv (HuScFv) were produced.•HuScFv inhibited replication of influenza viruses of types A and B and A subtypes.•One HuScFv bound to NS1 R…”
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13
Heterosubtypic immunity to influenza mediated by liposome adjuvanted H5N1 recombinant protein vaccines
Published in Vaccine (24-09-2010)“…Abstract A non-egg, non-culture based influenza vaccine that intervenes large influenza outbreaks and protects against heterosubtypic infections is needed…”
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14
Cell Penetrable Humanized-VH/V.sub.HH That Inhibit RNA Dependent RNA Polymerase of HCV
Published in PloS one (08-11-2012)“…NS5B is pivotal RNA dependent RNA polymerase (RdRp) of HCV and NS5B function interfering halts the virus infective cycle. This work aimed to produce cell…”
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Journal Article -
15
Cell Penetrable Humanized-VH/V.sub.HH That Inhibit RNA Dependent RNA Polymerase
Published in PloS one (08-11-2012)“…NS5B is pivotal RNA dependent RNA polymerase (RdRp) of HCV and NS5B function interfering halts the virus infective cycle. This work aimed to produce cell…”
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16
Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication
Published in Virology journal (14-05-2013)“…BACKGROUND: Novel effective anti-influenza agent that tolerates influenza virus antigenic variation is needed. Highly conserved influenza virus M2 protein has…”
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Production of Human Monoclonal ScFv that Bind to Different Functional Domains of M2 and Inhibit H5N1 Influenza Virus Replication
Published in Frontiers in immunology (2013)“…Abstract only…”
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18
Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza A virus subtype H5N1
Published in Antiviral therapy (01-01-2009)“…Human antibodies that interfere with the biological activity of haemagglutinins (HAs) of influenza viruses have high potential as an antiviral agent. Human…”
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Human monoclonal ScFv specific to NS1 protein inhibits replication of influenza viruses across types and subtypes
Published in Frontiers in immunology (2013)“…Abstract only…”
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20
Human single chain monoclonal antibody that recognizes matrix protein of heterologous influenza A virus subtypes
Published in Journal of virological methods (01-07-2009)“…Matrix protein (M1) is predominant and has pivotal role in the influenza A virus replication and assembly. It is therefore an attractive target for antiviral…”
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