Search Results - "Mando, Pablo"
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The BA-BCS 2021: An Initial “Trial” for Integrating Basic Science and Medical Progress on Breast Cancer in a Latin-American Country
Published in Journal of mammary gland biology and neoplasia (01-09-2021)“…The first Buenos Aires Breast Cancer Symposium (BA-BCS) was held in a virtual format, between the 17 th and the 21 st of May 2021. The main goal of the meeting…”
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Higher risk of recurrence in early-stage breast cancer patients with increased levels of ribosomal protein S6
Published in Scientific reports (24-10-2024)“…PI3K/AKT/mTOR pathway is implicated in breast cancer progression and recurrence. The identification of PIK3CA and AKT1 mutations and loss of PTEN serve as…”
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Phenotypic and functional analysis in HER2+ targeted therapy of human NK cell subpopulation according to the expression of FcεRIγ and NKG2C in breast cancer patients
Published in Cancer Immunology, Immunotherapy (01-08-2023)“…Adaptive NK cells constitute an NK cell subpopulation, which expands after human cytomegalovirus (HCMV) infection. This subpopulation has stronger production…”
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LuciA-15 - a real-world prospective study of PARP inhibitors for the treatment of patients with HER-2 negative metastatic breast cancer with germline and/or somatic mutation of BRCA genes or homologous recombination repair related genes
Published in Ecancermedicalscience (2023)“…Poly(adenosine diphosphate-ribose) polymerase inhibitors (PARPi) improve progression free survival among patients with HER2 negative (HER2-ve) advanced breast…”
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5
High neutrophil to lymphocyte ratio and decreased CD69 + NK cells represent a phenotype of high risk in early-stage breast cancer patients
Published in OncoTargets and therapy (01-01-2018)“…Breast cancer (BC) is a highly heterogeneous disease presenting a broad range of clinical and molecular characteristics. In the past years, a growing body of…”
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Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
Published in Breast (Edinburgh) (01-12-2021)“…The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of…”
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7
Analysis of adverse events attribution and reporting in cancer clinical trials: A systematic review
Published in Critical reviews in oncology/hematology (01-04-2021)“…[Display omitted] •Drug safety investigation is crucial in cancer clinical trials.•We reviewed adverse events (AEs) reporting and attribution process in…”
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Assessing the methodological quality of quality-of-life analyses in first-line non-small cell lung cancer trials: A systematic review
Published in Critical reviews in oncology/hematology (01-08-2022)“…Non-cytotoxic therapy has changed the treatment paradigm for advanced non-small cell lung cancer (NSCLC) patients. With unique mechanisms of action, these…”
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In-Depth Analysis of the Peripheral Immune Profile of HER2+ Breast Cancer Patients on Neoadjuvant Treatment with Chemotherapy Plus Trastuzumab Plus Pertuzumab
Published in International journal of molecular sciences (27-08-2024)“…Currently, therapy for early-stage human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) is based on the combination of trastuzumab and…”
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10
Peripheral changes in immune cell populations and soluble mediators after anti-PD-1 therapy in non-small cell lung cancer and renal cell carcinoma patients
Published in Cancer Immunology, Immunotherapy (01-10-2019)“…Patients with non-small cell lung cancer (NSCLC) and renal cell carcinoma (RCC) have shown benefit from anti-PD-1 therapies. However, not all patients…”
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Burnout syndrome in medical oncologists during the COVID-19 pandemic: Argentinian national survey
Published in Ecancermedicalscience (2021)“…Burnout (BO) syndrome is a condition that results in physical and mental distress. The current COVID-19 pandemic is strongly affecting the mental health of the…”
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12
HER2-Directed Therapy in Advanced Breast Cancer: Benefits and Risks
Published in OncoTargets and therapy (01-01-2023)“…Around 20% of breast cancers are associated with amplification or overexpression of human epidermal growth factor receptor 2 (HER2). In this setting,…”
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13
Prevalence of hepatitis E virus in children from Northeast of Argentina
Published in Journal of medical virology (01-06-2021)“…The aim of this study was to assess the prevalence of hepatitis E virus (HEV) in a young population from the Northeast region of Argentina. Four hundred and…”
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14
Breast Cancer in Young Women Presents With More Aggressive Pathologic Characteristics: Retrospective Analysis From an Argentine National Database
Published in JCO global oncology (01-04-2020)“…Multiple studies have reported that breast cancer in young patients is associated with aggressive characteristics, and it is suggested that prognosis is worse…”
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Determining Clinicopathologic Factors That Influence Treatment in Advanced Breast Cancer in Argentina After CDK4/6 Inhibitors
Published in JCO global oncology (01-09-2024)“…The optimal treatment sequence for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) after…”
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Lack of Prognostic Value of Pretreatment Neutrophil-to-Lymphocyte Ratio in Early Breast Cancer
Published in Breast care (Basel, Switzerland) (01-12-2022)“…Background: Breast cancer is a highly heterogeneous disease with large differences in the risk of recurrence. An elevated neutrophil-to-lymphocyte ratio (NLR)…”
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17
A Theoretical View of Ovarian Cancer Relapse
Published in European Medical Journal (Chelmsford, England) (31-08-2017)“…Ovarian cancer (OC) is a disease that almost invariably relapses even after optimal primary cytoreductive surgery and standard first-line platinum-based…”
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Appraising the quality of meta-analysis for breast cancer treatment in the adjuvant setting: A systematic review
Published in Cancer treatment and research communications (2021)“…•Methodological quality of early breast cancer adjuvant treatment is highly variable.•Correlations between journal impact factor or citation rate and AMSTAR…”
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High Histologic Grade and High Ki-67 Expression Predict Phenotypic Alterations in Node Metastasis in Primary Breast Cancers
Published in Journal of breast cancer (01-06-2017)“…Several studies have shown that estrogen receptor (ER) and progesterone receptor (PR) expression and human epidermal growth factor receptor 2 (HER2) expression…”
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Predictive Factors for Non-Sentinel Lymph Node Metastasis in Patients with ACOSOG Z0011 Criteria
Published in Breast care (Basel, Switzerland) (01-12-2018)“…Background: Nodal staging constitutes an element of great importance in the treatment planning for early breast cancer. The ACOSOG Z0011 trial demonstrated…”
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