Search Results - "Mandhane, Sanjay N"

Syringic Acid Ameliorates Cardiac, Hepatic, Renal and Neuronal Damage Induced by Chronic Hyperglycaemia in Wistar Rats: A Behavioural, Biochemical and Histological Analysis by Mirza, Anwarbaig C, Panchal, Shital S, Allam, Ahmed A, Othman, Sarah I, Satia, Milan, Mandhane, Sanjay N

“…This study investigated the effects of syringic acid (SA) on renal, cardiac, hepatic, and neuronal diabetic complications in streptozotocin-induced neonatal…”
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Development and characterization of liposomal formulation of bortezomib by Deshantri, Anil K., Metselaar, Josbert M., Zagkou, Stavroula, Storm, Gert, Mandhane, Sanjay N., Fens, Marcel H.A.M., Schiffelers, Raymond M.

“…[Display omitted] Bortezomib is a proteasome inhibitor used for the treatment of multiple myeloma. The poor pharmacokinetic profile and off-target adverse…”
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Complete Tumor Regression by Liposomal Bortezomib in a Humanized Mouse Model of Multiple Myeloma by Deshantri, Anil K., Fens, Marcel H.A.M., Ruiter, Ruud W.J., Metselaar, Josbert M., Storm, Gert, Mandhane, Sanjay N., Graat, Gerard H.M., Lentjes, Eef G.W., Yuan, Huipin, Bruijn, Joost D., Mutis, Tuna, Martens, Anton C.M., Groen, Richard W.J., Schiffelers, Raymond M.

“…Supplemental Digital Content is available in the text…”
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Nanomedicines for the treatment of hematological malignancies by Deshantri, Anil K., Varela Moreira, Aida, Ecker, Veronika, Mandhane, Sanjay N., Schiffelers, Raymond M., Buchner, Maike, Fens, Marcel H.A.M.

“…Hematological malignancies (HM) are a collection of malignant transformations originating from cells in the primary or secondary lymphoid organs. Leukemia,…”
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Allergic rhinitis: An update on disease, present treatments and future prospects by Mandhane, Sanjay N., Shah, Jigar H., Thennati, Rajamannar

“…Allergic rhinitis (AR) is an inflammation of nasal mucosa mediated by IgE-associated processes occurring independently, or concurrently with asthma. AR is…”
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Timed pentylenetetrazol infusion test: A comparative analysis with s.c.PTZ and MES models of anticonvulsant screening in mice by Mandhane, Sanjay N, Aavula, Keerthikumar, Rajamannar, T

“…Summary The intravenous pentylenetetrazol (i.v.PTZ) seizure test provides threshold dose for induction of seizures in individual animals. In the present study,…”
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Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma by Deshantri, Anil K., Fens, Marcel H., Ruiter, Ruud W.J., Metselaar, Josbert M., Storm, Gert, van Bloois, Louis, Varela-Moreira, Aida, Mandhane, Sanjay N., Mutis, Tuna, Martens, Anton C.M., Groen, Richard W.J., Schiffelers, Raymond M.

“…Glucocorticoids are the cornerstone in the clinic for treatment of hematological malignancies, including multiple myeloma. Nevertheless, poor pharmacokinetic…”
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Validation of guinea pig model of allergic rhinitis by oral and topical drugs by Bahekar, Prashant C., Shah, Jigar H., Ayer, Upendra B., Mandhane, Sanjay N., Thennati, Rajamannar

“…Ovalbumin-induced guinea pig model of rhinitis was assessed for its utility in the studies of rhinitis. Systemic sensitization and challenge with…”
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Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H by Mandhane, Sanjay N, Shah, Jigar H, Bahekar, Prashant C, Mehetre, Sameer V, Pawar, Chandrashekhar A, Bagad, Ashish S, Chidrewar, Gajanan U, Rao, Chitturi Trinadha, Rajamannar, Thennati

“…The anti-inflammatory potential of antihistamines has significant clinical utility. Long-term pharmacotherapy of so-called 'safe' antihistamines may be…”
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Preclinical Efficacy and Safety Pharmacology of SUN-1334H, a Potent Orally Active Antihistamine Agent by Mandhane, Sanjay N., Ayer, Upendra B., Midha, Ajay S., Rao, Chitturi Trinadha, Rajamannar, Thennati

“…Methods: In vitro antihistamine activity and selectivity of SUN-1334H was evaluated in a panel of receptor and enzyme assays and functional assays using…”
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Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats by MANDHANE, S. N, CHOPDE, C. T, GHOSH, A. K

“…The effect of adenosine A1 and A2 receptor agonists and antagonists was investigated on haloperidol-induced catalepsy in rats. Pretreatment (i.p.) with the…”
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Adenosinergic modulation of 3α-hydroxy-5α-pregnan-20-one induced catalepsy in mice by MANDHANE, S. N, KHISTI, R. T, CHOPDE, C. T

“…Rationale: Neurosteroid 3α, 5α THP, a positive allosteric modulator of the GABAA receptor Cl– ionophore complex, induces catalepsy-like dopamine antagonists,…”
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Effect of serotonergic agents on adenosine A2 receptor mediated catalepsy in mice by MANDHANE, S. N, KHISTI, R. T, CHOPDE, C. T

“…The effect of serotonergic agents was studied on the adenosine A2 receptor agonist NECA-induced catalepsy in mice. The 5-HT releaser fenfluramine, the 5-HT1A…”
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Effect of serotonergic agents on adenosine A 2 receptor mediated catalepsy in mice by Mandhane, Sanjay N., Khisti, Rahul T., Chopde, Chandrabhan T.

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Adenosine A 2 receptors modulate haloperidol-induced catalepsy in rats by Mandhane, Sanjay N, Chopde, Chandrabhan T, Ghosh, Anuradha K

“…The effect of adenosine A 1 and A 2 receptor agonists and antagonists was investigated on haloperidol-induced catalepsy in rats. Pretreatment (i.p.) with the…”
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GABAergic agents modify imipramine analgesia by Ballal, P M, Mandhane, S N, Chopde, C T, Muthal, A V

“…The influence of GABA agonists and antagonists on analgesic activity of imipramine (IMA, 20 mg/kg, ip) was studied using the hotplate method. Administration of…”
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