Search Results - "Manders, Liselot"

Elevated α-synuclein levels inhibit mitophagic flux by Kinnart, Inge, Manders, Liselot, Heyninck, Thibaut, Imberechts, Dorien, Praschberger, Roman, Schoovaerts, Nils, Verfaillie, Catherine, Verstreken, Patrik, Vandenberghe, Wim

“…The pathogenic effect of SNCA gene multiplications indicates that elevation of wild-type α-synuclein levels is sufficient to cause Parkinson’s disease (PD)…”
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DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy by Imberechts, Dorien, Kinnart, Inge, Wauters, Fieke, Terbeek, Joanne, Manders, Liselot, Wierda, Keimpe, Eggermont, Kristel, Madeiro, Rodrigo Furtado, Sue, Carolyn, Verfaillie, Catherine, Vandenberghe, Wim

“…Loss-of-function mutations in the PRKN, PINK1 and PARK7 genes (encoding parkin, PINK1 and DJ-1, respectively) cause autosomal recessive forms of Parkinson's…”
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