Search Results - "Mander, Alastair"
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Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin
Published in Diabetes care (01-10-2013)“…To investigate the associations of metformin, serum vitamin B12, calcium supplements, and cognitive impairment in patients with diabetes. Participants were…”
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Cognitive impairment and vitamin B12: a review
Published in International psychogeriatrics (01-04-2012)“…This review examines the associations between low vitamin B12 levels, neurodegenerative disease, and cognitive impairment. The potential impact of…”
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Predictors of Mortality in Dementia: The PRIME Study
Published in Journal of Alzheimer's disease (23-05-2016)“…Dementia is a terminal illness. While various baseline characteristics of patients, such as age, sex, and dementia severity, are known to predict mortality,…”
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Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts
Published in Journal of Alzheimer's disease (01-01-2014)“…Folate fortification of food aims to reduce the number of babies born with neural tube defects, but has been associated with cognitive impairment when vitamin…”
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Effect of APOE Genotype on Amyloid Deposition, Brain Volume, and Memory in Cognitively Normal Older Individuals
Published in Journal of Alzheimer's disease (01-01-2017)“…The association between the apolipoprotein E (APOE) ɛ4 allele and high risk of developing Alzheimer's disease (AD) dementia before the age of 80 has been…”
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Mortality in Mild Cognitive Impairment: A Longitudinal Study in Memory Clinics
Published in Journal of Alzheimer's disease (23-08-2016)“…Patients with mild cognitive impairment (MCI) are at greater risk of mortality than the general population. Comparatively little research has examined…”
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A revolution in drug approval practices is required
Published in BMJ (Online) (26-11-2012)“…The manufacturer could thus market the drug and start to recoup its investment, while the public and medical community obtain further data on the role and…”
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Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months
Published in PloS one (02-10-2015)“…High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older…”
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More adverse neurological consequences of metformin-induced vitamin B12 deficiency
Published in Southern medical journal (Birmingham, Ala.) (01-07-2011)Get full text
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Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-12-2019)“…Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration. While elevated amyloid β (Aβ) deposition…”
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Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease
Published in Neuroscience letters (13-03-1998)“…Serum levels of interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) were measured in 41 patients (23 female and 18 male, mean age 72.5 years) with…”
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Fluoxetine induced dyskinesia
Published in Australian and New Zealand journal of psychiatry (01-06-1994)“…A case of fluoxetine induced dyskinesia in an elderly woman with previous use of low dose haloperidol is described. In contrast to neuroleptic induced tardive…”
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