Search Results - "Mandarim‐de‐Lacerda, Carlos A."

Rosuvastatin limits the activation of hepatic stellate cells in diet‐induced obese mice by Marinho, Thatiany de Souza, Kawasaki, Adriana, Bryntesson, Marcus, Souza‐Mello, Vanessa, Barbosa‐da‐Silva, Sandra, Aguila, Marcia B., Mandarim‐de‐Lacerda, Carlos A.

“…Aim The aim of this study was to investigate the effects of rosuvastatin in a model of diet‐induced obesity and non‐alcoholic fatty liver disease, with…”
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Sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) plus glucagon‐like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase‐4 inhibitor combination in treating obese mice metabolic dysfunction‐associated steatotic liver disease (MASLD) by Reis‐Barbosa, Pedro H., Mandarim‐de‐Lacerda, Carlos A.

“…Background Monotherapy to treat obesity‐associated liver insult is limited. Objectives In diet‐induced obese mice showing metabolic dysfunction‐associated…”
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The dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 receptor agonist tirzepatide effects on body weight evolution, adiponectin, insulin and leptin levels in the combination of obesity, type 2 diabetes and menopause in mice by Reis‐Barbosa, Pedro H., Marcondes‐de‐Castro, Ilitch, Marinho, Thatiany S., Aguila, Marcia Barbosa, Mandarim‐de‐Lacerda, Carlos A.

“…Aim Tirzepatide (Tzp), a novel dual agonist glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1, is approved for treating insulin resistance…”
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Tirzepatide, a dual receptor agonist of glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1, enhances β‐cell survival and maintenance markers in obese diabetic ovariectomized mice by Reis‐Barbosa, Pedro H., Aguila, Marcia Barbosa, Mandarim‐de‐Lacerda, Carlos A.

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Semaglutide (GLP‐1 receptor agonist) stimulates browning on subcutaneous fat adipocytes and mitigates inflammation and endoplasmic reticulum stress in visceral fat adipocytes of obese mice by Martins, Fabiane F., Marinho, Thatiany S., Cardoso, Luiz E. M., Barbosa‐da‐Silva, Sandra, Souza‐Mello, Vanessa, Aguila, Marcia B., Mandarim‐de‐Lacerda, Carlos A.

“…Semaglutide (GLP‐1 agonist) was approved for treating obesity. Although the effects on weight loss and metabolism are known, the responses of adipocytes to…”
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A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet by Fraulob, Julio C., Ogg-Diamantino, Rebeca, Fernandes-Santos, Caroline, Aguila, Marcia Barbosa, Mandarim-de-Lacerda, Carlos A.

“…Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic syndrome (MetS). The purpose is to assess the suitability of a diet-induced…”
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Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL/6 mice by Ludgero-Correia, Antonio, B.Sc., M.Sc, Aguila, Marcia B., R.D., Ph.D, Mandarim-de-Lacerda, Carlos A., M.D., Ph.D, Faria, Tatiane S., B.Sc., Ph.D

“…Abstract Objective We hypothesized that a high-fat (HF) diet aggravates ovariectomy-related complications. To test this hypothesis, ovariectomized (OVX) mice…”
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Effects of a Diet Rich in n-3 Polyunsaturated Fatty Acids on Hepatic Lipogenesis and Beta-Oxidation in Mice by Bargut, Thereza C. Lonzetti, Frantz, Eliete D. C., Mandarim-de-Lacerda, Carlos A., Aguila, Marcia Barbosa

“…Here, we investigate whether a diet rich in fish oil can lead to the development of hepatic alterations associated with non-alcoholic fatty liver disease…”
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Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring by Gregorio, Bianca M., RD, PhD, Souza-Mello, Vanessa, RD, PhD, Carvalho, Jorge J., PhD, Mandarim-de-Lacerda, Carlos A., MD, PhD, Aguila, Marcia B., RD, PhD

“…Objective This work aimed to verify the hypothesis that maternal intake of high-fat diet in critical periods of pregnancy and/or suckling period predisposes…”
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Protein restriction during gestation and/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats by Pinheiro, Alessandra R, Salvucci, Isadora D M, Aguila, Marcia B, Mandarim-de-Lacerda, Carlos A

“…Substantial evidence suggests that poor intrauterine milieu elicited by maternal nutritional disturbance may programme susceptibility in the fetus to later…”
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Metformin enhances mitochondrial biogenesis and thermogenesis in brown adipocytes of mice by Karise, Iara, Bargut, Thereza Cristina, del Sol, Mariano, Aguila, Marcia Barbosa, Mandarim-de-Lacerda, Carlos A.

“…Norepinephrine binds to the beta three adrenergic receptors. It stimulates the expression of PGC1alpha which in turn acts in several ways: it increases UCP1…”
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Liver damage is not reversed during the lean period in diet-induced weight cycling in mice by Barbosa-da-Silva, Sandra, da Silva, Natalia C., Aguila, Marcia B., Mandarim-de-Lacerda, Carlos A.

“…Aim Weight cycling (WC) is frequent in obesity treatment. We evaluated the degree of regression of the liver damage in WC. Methods C57BL/6 male mice received…”
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Effects of liraglutide in hypothalamic arcuate nucleus of obese mice by Barreto‐Vianna, Andre R.C., Aguila, Marcia B., Mandarim‐de‐Lacerda, Carlos A.

“…Objective The neuroprotective effects of liraglutide (200 μg/kg, twice daily, subcutaneous administration) in the hypothalamic arcuate nucleus (ARC) of…”
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Weight cycling enhances adipose tissue inflammatory responses in male mice by Barbosa-da-Silva, Sandra, Fraulob-Aquino, Julio C, Lopes, Jessica R, Mandarim-de-Lacerda, Carlos A, Aguila, Marcia B

“…Obesity is associated with low-grade chronic inflammation attributed to dysregulated production, release of cytokines and adipokines and to dysregulated…”
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Hepatic adverse effects of fructose consumption independent of overweight/obesity by Schultz, Alini, Neil, Debora, Aguila, Marcia B, Mandarim-de-Lacerda, Carlos A

“…The chronic intake of fructose has been linked to insulin resistance, obesity, dyslipidemia and nonalcoholic fatty liver disease (NAFLD), which in turn, may…”
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Obese fathers lead to an altered metabolism and obesity in their children in adulthood: review of experimental and human studies by Ornellas, Fernanda, Carapeto, Priscila V., Mandarim-de-Lacerda, Carlos A., Aguila, Marcia B.

“…To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. A…”
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Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet by Souza-Mello, Vanessa, Gregório, Bianca M, Cardoso-de-Lemos, Fernando S, de Carvalho, Laís, Aguila, Márcia B, Mandarim-de-Lacerda, Carlos A

“…The aim of the present study was to evaluate the effects of monotherapies and combinations of drugs on insulin sensitivity, adipose tissue morphology, and…”
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Stereological tools in biomedical research by Mandarim-de-Lacerda, Carlos A

“…Stereological studies are more and more frequent in literature, particularly in the development/evolution, pathology, and neurosciences areas. The stereology…”
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The inflammatory profile and liver damage of a sucrose-rich diet in mice by Oliveira, Liliane Soares C., Santos, Daiane A., Barbosa-da-Silva, Sandra, Mandarim-de-Lacerda, Carlos A., Aguila, Marcia B.

“…It is still unclear if an isoenergetic, sucrose-rich diet leads to health consequences. To investigate the effects of excessive sucrose within an isoenergetic…”
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Maternal vitamin D deficiency delays glomerular maturity in F1 and F2 offspring by Nascimento, Fernanda A M, Ceciliano, Thais C, Aguila, Marcia B, Mandarim-de-Lacerda, Carlos A

“…There is a high prevalence of vitamin D insufficiency in women of reproductive age. This work studied the first two generations of offspring (F1 and F2) of…”
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