Search Results - "Mandalakas, Anna M"

Child contact management in high tuberculosis burden countries: A mixed-methods systematic review by Szkwarko, Daria, Hirsch-Moverman, Yael, Du Plessis, Lienki, Du Preez, Karen, Carr, Catherine, Mandalakas, Anna M

“…Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Considering the World Health Organization recommendation to implement child…”
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Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis by Detjen, Anne K, Dr, DiNardo, Andrew R, MD, Leyden, Jacinta, Steingart, Karen R, MD, Menzies, Dick, MD, Schiller, Ian, MSc, Dendukuri, Nandini, PhD, Mandalakas, Anna M, MD

“…Summary Background Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of…”
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Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting by Chegou, Novel N, Detjen, Anne K, Thiart, Lani, Walters, Elisabetta, Mandalakas, Anna M, Hesseling, Anneke C, Walzl, Gerhard

“…The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified…”
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Paediatric tuberculosis – new advances to close persistent gaps by Marais, Ben J., Verkuijl, Sabine, Casenghi, Martina, Triasih, Rina, Hesseling, Anneke C., Mandalakas, Anna M., Marcy, Olivier, Seddon, James A., Graham, Stephen M., Amanullah, Farhana

“…•Children are over-represented among TB deaths; most dying without accessing TB care.•Major gaps persist in TB preventive treatment (TPT) provision and TB case…”
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Predictors of suboptimal adherence to isoniazid preventive therapy among adolescents and children living with HIV by Kay, Alexander W, Thivalapill, Neil, Skinner, Donald, Dube, Gloria Sisi, Dlamini, Nomathemba, Mzileni, Bulisile, Fuentes, Patricia, Ustero, Pilar, Adams, Lisa V, Mandalakas, Anna M

“…This study identified factors associated with adherence to a 6-month isoniazid preventive therapy (IPT) course among adolescents and children living with HIV…”
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Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa by Mandalakas, Anna M, Kay, Alexander W, Bacha, Jason M, Devezin, Tara, Golin, Rachel, Simon, Katherine R, Dhillon, Dilsher, Dlamini, Sandile, DiNardo, Andrew, Matshaba, Mogo, Sanders, Jill, Thahane, Lineo, Amuge, Pauline M, Ahmed, Saeed, Sekadde, Moorine P, Fida, Neway G, Lukhele, Bhekumusa, Chidah, Nodumo, Damba, David, Mhango, Joseph, Chodota, Moses, Matsoso, Makhorong, Kayabu, Angelina, Wanless, Richard S, Schutze, Gordon E

“…HIV-infected children and adolescents are at increased risk for tuberculosis (TB). Antiretroviral therapy (ART) reduces TB risk in HIV-infected adults, but its…”
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Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines by Murray, Kristy O, Castillo-Carandang, Nina T, Mandalakas, Anna M, Cruz, Andrea T, Leining, Lauren M, Gatchalian, Salvacion R

“…In 2013, a severe earthquake and typhoon affected Bohol, Philippines. To assess the postdisaster risk for emergence of Mycobacterium tuberculosis infection in…”
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Schistosoma, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania by Said, Khadija, Hella, Jerry, Knopp, Stefanie, Nassoro, Tatu, Shija, Neema, Aziz, Fatma, Mhimbira, Francis, Schindler, Christian, Mwingira, Upendo, Mandalakas, Anna M, Manji, Karim, Tanner, Marcel, Utzinger, Jürg, Fenner, Lukas

“…Despite the high prevalence of helminth infections among preschool-aged children, control programs in sub-Saharan countries primarily focus on school-aged…”
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The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study by Golla, Vera, Snow, Kathryn, Mandalakas, Anna M, Schaaf, H Simon, Du Preez, Karen, Hesseling, Anneke C, Seddon, James A

“…The relative fitness of organisms causing drug-susceptible (DS) and multidrug-resistant (MDR) tuberculosis (TB) is unclear. We compared the risk of TB…”
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HIV-Associated Tuberculosis in Children and Adolescents: Evolving Epidemiology, Screening, Prevention and Management Strategies by Kay, Alexander W, Rabie, Helena, Maleche-Obimbo, Elizabeth, Sekadde, Moorine Penninah, Cotton, Mark F, Mandalakas, Anna M

“…Children and adolescents living with HIV continue to be impacted disproportionately by tuberculosis as compared to peers without HIV. HIV can impact TB…”
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Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective by van Wyk, Susan S, Reid, Anthony J, Mandalakas, Anna M, Enarson, Donald A, Beyers, Nulda, Morrison, Julie, Hesseling, Anneke C

“…The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five…”
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Use of string test and stool specimens to diagnose pulmonary tuberculosis by DiNardo, Andrew R, Hahn, Andrew, Leyden, Jacinta, Stager, Charles, Baron, Ellen Jo, Graviss, Edward A, Mandalakas, Anna M, Guy, Elizabeth

“…Highlights • The diagnosis of pulmonary tuberculosis (PTB) remains challenging due to the slow time to culture positivity and challenges collecting adequate…”
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Does an isoniazid prophylaxis register improve tuberculosis contact management in South African children? by van Soelen, Nelda, du Preez, Karen, van Wyk, Susan S, Mandalakas, Anna M, Enarson, Don A, Reid, Anthony J, Hesseling, Anneke C

“…We compared the change in child household contact management of pulmonary tuberculosis (TB) cases before and after the implementation of an isoniazid…”
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100 years of Mycobacterium bovis bacille Calmette-Guérin by Lange, Christoph, Aaby, Peter, Behr, Marcel A, Donald, Peter R, Kaufmann, Stefan H E, Netea, Mihai G, Mandalakas, Anna M

“…Mycobacterium bovis bacille Calmette-Guérin (BCG), an experimental vaccine designed to protect cattle from bovine tuberculosis, was administered for the first…”
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Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study by Golla, Vera, Snow, Kathryn, Mandalakas, Anna M, Schaaf, H Simon, Du Preez, Karen, Hesseling, Anneke C, Seddon, James A

“…After publication of the original article [1] the authors noted that the following errors had occurred…”
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Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study by van Soelen, Nelda, Mandalakas, Anna M, Kirchner, H Lester, Walzl, Gerhard, Grewal, Harleen M S, Jacobsen, Marc, Hesseling, Anneke C

“…M.tuberculosis (M.tb) is associated with enhanced T helper cell type 1 (Th1) immune responses while helminth infection is associated with T helper cell type 2…”
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Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children by Kay, Alexander W, González Fernández, Lucia, Takwoingi, Yemisi, Eisenhut, Michael, Detjen, Anne K, Steingart, Karen R, Mandalakas, Anna M

“…Every year, at least one million children become ill with tuberculosis and around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health…”
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HIV Progression Perturbs the Balance of the Cell-Mediated and Anti-Inflammatory Adaptive and Innate Mycobacterial Immune Response by Makedonas, George, Orange, Jordan S., Hlatshwayo, Makhosazana, Ustero, Piluca, Mndzebele, Temhlanga, Mtetwa, Godwin, Maphalala, Gugu, Mandalakas, Anna M., DiNardo, Andrew R., Mace, Emily M.

“…Introduction. Our objective is to understand how HIV infection increases the risk of progression from latent tuberculosis (TB) to active disease. We understand…”
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Transition to Dolutegravir Is Associated With an Increase in the Rate of Body Mass Index Change in a Cohort of Virally Suppressed Adolescents by Thivalapill, Neil, Simelane, Tandzile, Mthethwa, Nobuhle, Dlamini, Sandile, Lukhele, Bhekumusa, Okello, Velephi, Kirchner, H Lester, Mandalakas, Anna M, Kay, Alexander W

“…Abstract Background Antiretroviral therapy (ART) regimens that contain dolutegravir (DTG) have been associated with increases in body mass index (BMI) in…”
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Tuberculosis prevention: current strategies and future directions by Vasiliu, Anca, Martinez, Leonardo, Gupta, Rishi K, Hamada, Yohhei, Ness, Tara, Kay, Alexander, Bonnet, Maryline, Sester, Martina, Kaufmann, Stefan H E, Lange, Christoph, Mandalakas, Anna M

“…An estimated one fourth of the world's population is infected with Mycobacterium tuberculosis, and 5-10% of those infected develop tuberculosis in their…”
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