Search Results - "Mandalakas, A M"

Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis [Review article] by MANDALAKAS, A. M, DETJEN, A. K, HESSELING, A. C, BENEDETTI, A, MENZIES, D

“…BACKGROUND: Children infected with Mycobacterium tuberculosis have significant risk of developing tuberculosis (TB) and can therefore benefit from preventive…”
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Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection by Mandalakas, A. M., Kirchner, H. L., Lombard, C., Walzl, G., Grewal, H. M. S., Gie, R. P., Hesseling, A. C.

“…SETTING: Cape Town, South Africa.OBJECTIVE: To develop a standardized, reliable measure of household tuberculosis (TB) exposure that considers child-specific…”
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Management of patients with multidrug-resistant tuberculosis by Lange, C., Aarnoutse, R. E., Alffenaar, J. W. C., Bothamley, G., Brinkmann, F., Costa, J., Chesov, D., van Crevel, R., Dedicoat, M., Dominguez, J., Duarte, R., Grobbel, H. P., Günther, G., Guglielmetti, L., Heyckendorf, J., Kay, A. W., Kirakosyan, O., Kirk, O., Koczulla, R. A., Kudriashov, G. G., Kuksa, L., van Leth, F., Magis-Escurra, C., Mandalakas, A. M., Molina-Moya, B., Peloquin, C. A., Reimann, M., Rumetshofer, R., Schaaf, H. S., Schön, T., Tiberi, S., Valda, J., Yablonskii, P. K., Dheda, K.

“…The emergence of multidrug-resistant tuberculosis (MDR-TB; defined as resistance to at least rifampicin and isoniazid) represents a growing threat to public…”
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Pasting together the preventive therapy puzzle [Short communication] by Skinner, D., Mandalakas, A. M.

“…In children, the effectiveness of preventive therapy (PT) for tuberculosis (TB) will always be dependent upon the care giver's behaviour, as this determines…”
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Highly discordant T cell responses in individuals with recent exposure to household tuberculosis by Hesseling, A C, Mandalakas, A M, Kirchner, H L, Chegou, N N, Marais, B J, Stanley, K, Zhu, X, Black, G, Beyers, N, Walzl, G

“…There are limited data comparing interferon-gamma release assays (IGRAs) for the detection of Mycobacterium tuberculosis infection in highly endemic settings…”
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High level of discordant IGRA results in HIV-infected adults and children by MANDALAKAS, A. M, HESSELING, A. C, CHEGOU, N. N, KIRCHNER, H. L, ZHU, X, MARAIS, B. J, BLACK, G. F, BEYERS, N, WALZL, G

“…SETTING: Tygerberg district, Western Cape Province, South Africa.OBJECTIVE: To measure the agreement of two interferon-gamma release assays (IGRAs) and the…”
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Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children by du Preez, K., Mandalakas, Kirchner, Grewal, Schaaf, van Wyk, Hesseling

“…BACKGROUND: Data on the association between exposure to environmental tobacco smoke (ETS) and Mycobacterium tuberculosis infection in children are limited…”
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Tuberculosis contact investigation in a high-burden setting: house or household? by Van Wyk, S. S., Mandalakas, A. M., Enarson, D. A., Gie, R. P., Beyers, N., Hesseling, A. C.

“…SETTING: A high tuberculosis (TB) burden setting, South Africa. Two frequently used definitions for 'household' are 1) 'all dwellings on the same plot of land…”
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Mycobacterial genotype is associated with disease phenotype in children by HESSELING, A. C, MARAIS, B. J, KIRCHNER, H. L, MANDALAKAS, A. M, BRITTLE, W, VICTOR, T. C, WARREN, R. M, SCHAAF, H. S

“…OBJECTIVE: To investigate the association between mycobacterial genotype and disease phenotype in children.METHODS: We describe hospitalised children diagnosed…”
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The need for effective drugs for TB prevention: set your goals high, and don´t stop till you get there by Lange, C., Kay, A., Mandalakas, A. M.

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Opportunities for chemoprophylaxis in children with culture-confirmed tuberculosis by Du Preez, K, Hesseling, A C, Mandalakas, A M, Marais, B J, Schaaf, H S

“…Background and objectives: Chemoprophylaxis is an effective strategy to prevent progression of tuberculosis (TB) in vulnerable children who have had contact…”
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Geospatial and hot spot analysis of paediatric tuberculosis infection in Bohol, Philippines by Leining, L. M., Gatchalian, S. R., Gunter, S. M., Castillo-Carandang, N. T., Mandalakas, A. M., Cruz, A. T., McCormick, J. B., Murray, K. O.

“…Abstract Tuberculosis (TB) in children is a critical public health issue. In Bohol, Philippines, we found a high tuberculin skin test (TST)-positive prevalence…”
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Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study by Wiseman, C. A., Mandalakas, A. M., Kirchner, H. L., Gie, R. P., Schaaf, H. S., Walters, E., Hesseling, A. C.

“…BACKGROUND: International (National Institutes of Health [NIH]) case definitions have been proposed for paediatric tuberculosis (TB) diagnostic studies. The…”
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Recording isoniazid preventive therapy delivery to children: operational challenges [Short communication] by Van Wyk, S S, Hamade, H, Hesseling, A C, Beyers, N, Enarson, D A, Mandalakas, A M

“…Despite recommendations to provide isoniazid preventive therapy (IPT) to eligible children aged <5 years who are in close contact with an infectious…”
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The need for effective drugs for TB prevention: set your goals high, and don’t stop till you get there by Lange, C., Kay, A., Mandalakas, A. M.

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Human Immunodeficiency Virus Status and Delayed-Type Hypersensitivity Skin Testing in Ugandan Children by Mandalakas, Anna Maria, Guay, Laura, Musoke, Philippa, Carroll-Pankhurst, Cindie, Olness, Karen N

“…In previous studies, delayed-type hypersensitivity (DTH) skin testing has been shown to be affected by several factors including nutritional status,…”
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West Nile virus epidemic, northeast Ohio, 2002 by Mandalakas, Anna M, Kippes, Christopher, Sedransk, Joseph, Kile, Jeffrey R, Garg, Asha, McLeod, John, Berry, Richard L, Marfin, Anthony A

“…Serum samples and sociodemographic data were obtained from 1,209 Ohio residents. West Nile virus immunoglobulin M (IgM) and IgG antibodies were detected by…”
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Outcomes in children treated for tuberculosis with the new dispersible fixed-dose combinations in Port Moresby by Apis, V., Landi, M., Graham, S. M., Islam, T., Amini, J., Sabumi, G., Mandalakas, A. M., Meae, T., du Cros, P., Shewade, H. D., Welch, H.

“…The new child-friendly fixed dose combinations (FDCs) were introduced at Port Moresby General Hospital, Papua New Guinea, in 2016 for the first-line treatment…”
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It's hard work, but it's worth it: the task of keeping children adherent to isoniazid preventive therapy by Skinner, D., Hesseling, A. C., Francis, C., Mandalakas, A. M.

“…SETTING: Isoniazid preventive therapy (IPT) offers children protection against tuberculosis (TB), but it has been difficult to implement, particularly in…”
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Development of tuberculosis infection control guidelines in a pediatric HIV clinic in sub-Saharan Africa by Carlucci, J. G., Jin, L., Sanders, J. E., Mohapi, E. Q., Mandalakas, A. M.

“…Setting: A well-established pediatric human immunodeficiency virus (HIV) clinic in Lesotho with initial infection control (IC) measures prioritizing…”
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