Search Results - "Mandalakas"

Child contact management in high tuberculosis burden countries: A mixed-methods systematic review by Szkwarko, Daria, Hirsch-Moverman, Yael, Du Plessis, Lienki, Du Preez, Karen, Carr, Catherine, Mandalakas, Anna M

“…Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Considering the World Health Organization recommendation to implement child…”
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Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis [Review article] by MANDALAKAS, A. M, DETJEN, A. K, HESSELING, A. C, BENEDETTI, A, MENZIES, D

“…BACKGROUND: Children infected with Mycobacterium tuberculosis have significant risk of developing tuberculosis (TB) and can therefore benefit from preventive…”
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Management of drug-resistant tuberculosis by Lange, Christoph, Dheda, Keertan, Chesov, Dumitru, Mandalakas, Anna Maria, Udwadia, Zarir, Horsburgh, C Robert

“…Drug-resistant tuberculosis is a major public health concern in many countries. Over the past decade, the number of patients infected with Mycobacterium…”
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Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting by Chegou, Novel N, Detjen, Anne K, Thiart, Lani, Walters, Elisabetta, Mandalakas, Anna M, Hesseling, Anneke C, Walzl, Gerhard

“…The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified…”
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Pediatric Post-TB Lung Disease: Ready for Prime Time? by Masekela, Refiloe, Mandalakas, Anna Maria

“…Masekela and Mandalakas discuss the study by Martinez and colleagues on pediatric post-tuberculosis (TB) lung disease. TB remains a disease of epidemic…”
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100 years of Mycobacterium bovis bacille Calmette-Guérin by Lange, Christoph, Aaby, Peter, Behr, Marcel A, Donald, Peter R, Kaufmann, Stefan H E, Netea, Mihai G, Mandalakas, Anna M

“…Mycobacterium bovis bacille Calmette-Guérin (BCG), an experimental vaccine designed to protect cattle from bovine tuberculosis, was administered for the first…”
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Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model by Heyckendorf, Jan, Marwitz, Sebastian, Reimann, Maja, Avsar, Korkut, DiNardo, Andrew, Günther, Gunar, Hoelscher, Michael, Ibraim, Elmira, Kalsdorf, Barbara, Kaufmann, Stefan H E, Kontsevaya, Irina, van Leth, Frank, Mandalakas, Anna Maria, Maurer, Florian P, Müller, Marius, Nitschkowski, Dörte, Olaru, Ioana D, Popa, Cristina, Rachow, Andrea, Rolling, Thierry, Rybniker, Jan, Salzer, Helmut J F, Sanchez-Carballo, Patricia, Schuhmann, Maren, Schaub, Dagmar, Spinu, Victor, Suárez, Isabelle, Terhalle, Elena, Unnewehr, Markus, Weiner, 3rd, January, Goldmann, Torsten, Lange, Christoph

“…The World Health Organization recommends standardised treatment durations for patients with tuberculosis. We identified and validated a host-RNA signature as a…”
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Management of patients with multidrug-resistant tuberculosis by Lange, C., Aarnoutse, R. E., Alffenaar, J. W. C., Bothamley, G., Brinkmann, F., Costa, J., Chesov, D., van Crevel, R., Dedicoat, M., Dominguez, J., Duarte, R., Grobbel, H. P., Günther, G., Guglielmetti, L., Heyckendorf, J., Kay, A. W., Kirakosyan, O., Kirk, O., Koczulla, R. A., Kudriashov, G. G., Kuksa, L., van Leth, F., Magis-Escurra, C., Mandalakas, A. M., Molina-Moya, B., Peloquin, C. A., Reimann, M., Rumetshofer, R., Schaaf, H. S., Schön, T., Tiberi, S., Valda, J., Yablonskii, P. K., Dheda, K.

“…The emergence of multidrug-resistant tuberculosis (MDR-TB; defined as resistance to at least rifampicin and isoniazid) represents a growing threat to public…”
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Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis by Detjen, Anne K, Dr, DiNardo, Andrew R, MD, Leyden, Jacinta, Steingart, Karen R, MD, Menzies, Dick, MD, Schiller, Ian, MSc, Dendukuri, Nandini, PhD, Mandalakas, Anna M, MD

“…Summary Background Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of…”
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Paediatric tuberculosis – new advances to close persistent gaps by Marais, Ben J., Verkuijl, Sabine, Casenghi, Martina, Triasih, Rina, Hesseling, Anneke C., Mandalakas, Anna M., Marcy, Olivier, Seddon, James A., Graham, Stephen M., Amanullah, Farhana

“…•Children are over-represented among TB deaths; most dying without accessing TB care.•Major gaps persist in TB preventive treatment (TPT) provision and TB case…”
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Predictors of suboptimal adherence to isoniazid preventive therapy among adolescents and children living with HIV by Kay, Alexander W, Thivalapill, Neil, Skinner, Donald, Dube, Gloria Sisi, Dlamini, Nomathemba, Mzileni, Bulisile, Fuentes, Patricia, Ustero, Pilar, Adams, Lisa V, Mandalakas, Anna M

“…This study identified factors associated with adherence to a 6-month isoniazid preventive therapy (IPT) course among adolescents and children living with HIV…”
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Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement by Domínguez, José, Boeree, Martin J, Cambau, Emmanuelle, Chesov, Dumitru, Conradie, Francesca, Cox, Vivian, Dheda, Keertan, Dudnyk, Andrii, Farhat, Maha R, Gagneux, Sebastien, Grobusch, Martin P, Gröschel, Matthias I, Guglielmetti, Lorenzo, Kontsevaya, Irina, Lange, Berit, van Leth, Frank, Lienhardt, Christian, Mandalakas, Anna M, Maurer, Florian P, Merker, Matthias, Miotto, Paolo, Molina-Moya, Barbara, Morel, Florence, Niemann, Stefan, Veziris, Nicolas, Whitelaw, Andrew, Horsburgh, Charles R, Lange, Christoph, Domínguez, Jose, Boeree, Martin J., Cambau, Emmanuelle, Chesov, Dumitru, Conradie, Francesca, Cox, Vivian, Dheda, Keertan, Dudnyk, Andrii, Farhat, Maha R., Gagneux, Sebastien, Grobusch, Martin P., Gröschel, Matthias I., Guglielmetti, Lorenzo, Kontsevaya, Irina, Lange, Berit, van Leth, Frank, Lienhardt, Christian, Mandalakas, Anna Maria, Maurer, Florian, Merker, Matthias, Miotto, Paolo, Molina-Moya, Barbara, Morel, Florence, Niemann, Stefan, Veziris, Nicolas, Whitelaw, Andrew, Horsburgh, Charles Robert, Lange, Christoph

“…Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-based methods being considered the gold standard for drug…”
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Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis by Martinez, Leonardo, Cords, Olivia, Liu, Qiao, Acuna-Villaorduna, Carlos, Bonnet, Maryline, Fox, Greg J, Carvalho, Anna Cristina C, Chan, Pei-Chun, Croda, Julio, Hill, Philip C, Lopez-Varela, Elisa, Donkor, Simon, Fielding, Katherine, Graham, Stephen M, Espinal, Marcos A, Kampmann, Beate, Reingold, Arthur, Huerga, Helena, Villalba, Julian A, Grandjean, Louis, Sotgiu, Giovanni, Egere, Uzochukwu, Singh, Sarman, Zhu, Limei, Lienhardt, Christian, Denholm, Justin T, Seddon, James A, Whalen, Christopher C, García-Basteiro, Alberto L, Triasih, Rina, Chen, Cheng, Singh, Jitendra, Huang, Li-Min, Sharma, Surendra, Hannoun, Djohar, del Corral, Helena, Mandalakas, Anna M, Malone, LaShaunda L, Ling, Du-Lin, Kritski, Afrânio, Stein, Catherine M, Vashishtha, Richa, Boulahbal, Fadila, Fang, Chi-Tai, Boom, W Henry, Netto, Eduardo Martins, Lemos, Antonio Carlos, Hesseling, Anneke C, Kay, Alexander, Jones-López, Edward C, Horsburgh, C Robert, Lange, Christoph, Andrews, Jason R

“…BCG vaccines are given to more than 100 million children every year, but there is considerable debate regarding the effectiveness of BCG vaccination in…”
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Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children by Kay, Alexander W, González Fernández, Lucia, Takwoingi, Yemisi, Eisenhut, Michael, Detjen, Anne K, Steingart, Karen R, Mandalakas, Anna M

“…Every year, at least one million children become ill with tuberculosis and around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health…”
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Tuberculosis prevention in children: a prospective community-based study in South Africa by Mandalakas, Anna M, Hesseling, Anneke C, Kay, Alexander, Du Preez, Karen, Martinez, Leonardo, Ronge, Lena, DiNardo, Andrew, Lange, Christoph, Kirchner, H Lester

“…Tuberculosis (TB) preventive therapy reduces TB risk in children. However, the effectiveness of TB preventive therapy in children living in high TB burden…”
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Emerging bedaquiline-resistant tuberculosis by Lange, Christoph, Vasiliu, Anca, Mandalakas, Anna M

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Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection by Mandalakas, A. M., Kirchner, H. L., Lombard, C., Walzl, G., Grewal, H. M. S., Gie, R. P., Hesseling, A. C.

“…SETTING: Cape Town, South Africa.OBJECTIVE: To develop a standardized, reliable measure of household tuberculosis (TB) exposure that considers child-specific…”
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Celebrating the life of Peter Nicholas Kazembe M.D., 1955-2020 by Mandalakas, A., Harries, A. D.

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BUTIMBA: Intensifying the Hunt for Child TB in Swaziland through Household Contact Tracing by Mandalakas, Anna Maria, Ngo, Katherine, Alonso Ustero, Pilar, Golin, Rachel, Anabwani, Florence, Mzileni, Bulisile, Sikhondze, Welile, Stevens, Robert

“…Limited data exists to inform contact tracing guidelines in children and HIV-affected populations. We evaluated the yield and additionality of household…”
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Pasting together the preventive therapy puzzle [Short communication] by Skinner, D., Mandalakas, A. M.

“…In children, the effectiveness of preventive therapy (PT) for tuberculosis (TB) will always be dependent upon the care giver's behaviour, as this determines…”
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