Search Results - "Mandal, Dindyal"
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1
Self-assembly of peptides to nanostructures
Published in Organic & biomolecular chemistry (14-06-2014)“…The formation of well-ordered nanostructures through self-assembly of diverse organic and inorganic building blocks has drawn much attention owing to their…”
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2
Design and Biological Evaluation of Cell-Penetrating Peptide–Doxorubicin Conjugates as Prodrugs
Published in Molecular pharmaceutics (04-02-2013)“…Doxorubicin (Dox) is a hydrophilic anticancer drug that has short retention time due to the efficient efflux in some cancer cells (e.g., ovarian adenocarcinoma…”
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3
Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations
Published in Molecules (Basel, Switzerland) (02-05-2020)“…1-(α,β-Alkene)-substituted phenylpyrazolopyrimidine derivatives with acetyl and functionalized phenyl groups at α- and β-positions, respectively, were…”
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4
Oleyl Conjugated Histidine-Arginine Cell-Penetrating Peptides as Promising Agents for siRNA Delivery
Published in Pharmaceutics (18-04-2022)“…Recent approvals of siRNA-based products motivated the scientific community to explore siRNA as a treatment option for several intractable ailments, especially…”
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5
Modified Linear Peptides Effectively Silence STAT-3 in Breast Cancer and Ovarian Cancer Cell Lines
Published in Pharmaceutics (01-02-2023)“…RNA interference (RNAi) has drawn enormous attention as a powerful tool because of its capability to interfere with mRNA and protein production. However,…”
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6
Cyclic peptide-capped gold nanoparticles for enhanced siRNA delivery
Published in Molecules (Basel, Switzerland) (28-08-2014)“…Previously, we have reported the synthesis of a homochiral l-cyclic peptide [WR]5 and its use for delivery of anti-HIV drugs and biomolecules. A physical…”
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Amphiphilic Cell-Penetrating Peptides Containing Natural and Unnatural Amino Acids as Drug Delivery Agents
Published in Cells (Basel, Switzerland) (29-03-2022)“…A series of cyclic peptides, [(DipR)(WR) ], [(DipR) (WR) ], [(DipR) (WR) ], [(DipR) (WR)], and [DipR] , and their linear counterparts containing arginine (R)…”
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Comparative Molecular Transporter Properties of Cyclic Peptides Containing Tryptophan and Arginine Residues Formed through Disulfide Cyclization
Published in Molecules (Basel, Switzerland) (02-06-2020)“…We have previously reported cyclic cell-penetrating peptides [WR] and [WR] as molecular transporters. To optimize further the utility of our developed peptides…”
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9
Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter
Published in Pharmaceutics (03-09-2020)“…The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic…”
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10
Surface Decorated Gold Nanoparticles by Linear and Cyclic Peptides as Molecular Transporters
Published in Molecular pharmaceutics (05-08-2013)“…Gold nanoparticles (AuNPs) were synthesized in situ in a green and rapid method from the reaction of reducing linear and cyclic peptides containing tryptophan…”
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Cyclic Peptide-Gadolinium Nanocomplexes as siRNA Delivery Tools
Published in Pharmaceuticals (Basel, Switzerland) (20-10-2021)“…We have recently reported that a cyclic peptide containing five tryptophan, five arginine, and one cysteine amino acids [(WR)5C], was able to produce…”
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Biosynthesis of Rutin Trihydrate Loaded Silica Nanoparticles and Investigation of Its Antioxidant, Antidiabetic and Cytotoxic Potentials
Published in Journal of inorganic and organometallic polymers and materials (2022)“…In the current study, customized SiNPs were synthesized using an adapted Stöber process and functionalized with silane for the loading of phytocompound rutin…”
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13
Cyclic Peptide-Gadolinium Nanoparticles for Enhanced Intracellular Delivery
Published in Pharmaceutics (21-08-2020)“…A cyclic peptide containing one cysteine and five alternating tryptophan and arginine amino acids [(WR)5C] was synthesized using Fmoc/tBu solid-phase…”
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14
Catechol Mediated Synthesis of Monometallic and Bimetallic Nanoparticles and Catalytic Efficiency of Monometallic Nanoparticles
Published in Catalysis letters (01-06-2023)“…Catechol is demonstrated as a versatile reducing agent/stabilizing agent for the facile and one pot synthesis of monometallic (Au, Se and Pd) and bimetallic…”
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The next frontier in hemorrhagic management: A comprehensive review on development of natural polymer-based injectable hydrogels as promising hemostatic dressings
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-10-2024)“…•Injectable hydrogels are excellent candidates for hemostatic dressings in both external and internal bleeding.•Their fabrication using natural biopolymers…”
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16
Biosynthesized gold nanoparticles as photocatalysts for selective degradation of cationic dye and their antimicrobial activity
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-09-2020)“…Plant extract generated gold nanoparticles exhibit significant potential in the selective removal of cationic dye in presence of sunlight and as antimicrobial…”
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Selective adsorption and removal of Congo red dye from waste water using catechol-stabilized reusable palladium nanoparticles
Published in Inorganic chemistry communications (01-09-2024)“…[Display omitted] •Catechol generated Pd nanoparticles have been demonstrated as efficient catalysts for dye degradation.•Newly developed Pd nanoparticles…”
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Anticancer Activity of Green Synthesized Manganese Doped Cerium Oxide Nanoparticles Prepared by Using Acacia Concinna Fruit Extract
Published in ChemistrySelect (Weinheim) (04-11-2024)“…Pure CeO2 and Ce1‐xMnxO2, where x = 0, 2, 4 and 6% w/w, were synthesized by sol‐gel method using Acacia Concinna fruit extract as a surfactant and stabilizing…”
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19
Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties
Published in Journal of medicinal chemistry (13-01-2022)“…We report the synthesis and antibacterial activities of a series of amphiphilic membrane-active peptides composed, in part, of various nongenetically coded…”
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Peptide generated anisotropic gold nanoparticles as efficient siRNA vectors
Published in International journal of pharmaceutics (30-05-2019)“…Peptide generated anisotropic gold nanoparticles are demonstrated as efficient siRNA carriers. Delivered GAPDH siRNA exhibits significant GAPDH gene…”
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