Search Results - "Mancuso, Gerardo"
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Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol
Published in Atherosclerosis (01-11-2004)“…It has been recently hypothesized that both TNFalpha and anti TNFalpha treatment have a stimulating effect on nitric oxide synthesis and release. Moreover, an…”
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Hepatic steatosis, carotid atherosclerosis and metabolic syndrome: the STEATO Study
Published in Journal of gastroenterology (01-11-2009)“…Purpose Hepatic steatosis is frequently observed in subjects with metabolic syndrome (MS). In type 2 diabetics, it is independently associated with…”
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Food contamination and cardiovascular disease: a narrative review
Published in Internal and emergency medicine (01-09-2024)“…Cardiovascular disease is a significant cause of morbidity and mortality among non-communicable diseases worldwide. Evidence shows that a healthy dietary…”
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Impact of electronic cigarettes (e-cigs) and heat-not-burn/heated tobacco products (HnB/HTP) on asthma and chronic obstructive pulmonary disease: a viewpoint of the Italian Society of Internal Medicine
Published in Internal and emergency medicine (01-10-2024)“…The association of cigarette smoking with several severe and very severe diseases (oncological, cardiovascular, respiratory) which have dramatic…”
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Defining Aging Phenotypes and Related Outcomes: Clues to Recognize Frailty in Hospitalized Older Patients
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-03-2017)“…Because frailty is a complex phenomenon associated with poor outcomes, the identification of patient profiles with different care needs might be of greater…”
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Mortality rate and risk factors for gastrointestinal bleeding in elderly patients
Published in European journal of internal medicine (01-03-2019)“…Gastrointestinal bleeding (GIB) is burdened by high mortality rate that increases with aging. Elderly patients may be exposed to multiple risk factors for GIB…”
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Adherence to antithrombotic therapy guidelines improves mortality among elderly patients with atrial fibrillation: insights from the REPOSI study
Published in Clinical research in cardiology (01-11-2016)“…Background Atrial fibrillation (AF) is associated with a substantial risk of thromboembolism and mortality, significantly reduced by oral anticoagulation…”
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Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients
Published in European journal of clinical investigation (01-04-2023)“…Background Hypertension management in older patients represents a challenge, particularly when hospitalized. Objective The objective of this study is to…”
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Drug–drug interactions involving CYP3A4 and p-glycoprotein in hospitalized elderly patients
Published in European journal of internal medicine (01-07-2019)“…Polypharmacy is very common in older patients and may be associated with drug-drug interactions. Hepatic cytochrome P450 (notably 3A4 subtype, CYP3A4) is a key…”
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Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry
Published in Acta diabetologica (01-09-2021)“…Aims The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the…”
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Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both
Published in Internal and emergency medicine (01-03-2023)“…Background and objective Chronic obstructive pulmonary disease (COPD) and heart failure (HF) mutually increase the risk of being present in the same patient,…”
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Statins, ACE/ARBs drug use, and risk of pneumonia in hospitalized older patients: a retrospective cohort study
Published in Internal and emergency medicine (01-04-2024)“…The aims of this study is to evaluate the association between angiotensin-converting enzyme inhibitor (ACE-I), angiotensin II receptor blocker (ARBs) and/or…”
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Pattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry
Published in Internal and emergency medicine (01-03-2021)“…Currently, chronic obstructive pulmonary disease (COPD) represents the fourth cause of death worldwide with significant economic burden. Comorbidities increase…”
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Prescription appropriateness of anti-diabetes drugs in elderly patients hospitalized in a clinical setting: evidence from the REPOSI Register
Published in Internal and emergency medicine (01-06-2023)“…Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of…”
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Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy between 2010 and 2016 (the REPOSI Register)
Published in Endocrine (01-02-2021)“…Purpose To evaluate clinical features, treatments, and outcomes of osteoporotic patients admitted to internal medicine and geriatric wards compared with…”
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Appropriateness of antiplatelet therapy for primary and secondary cardio‐ and cerebrovascular prevention in acutely hospitalized older people
Published in British journal of clinical pharmacology (01-11-2017)“…Aims Antiplatelet therapy is recommended for the secondary prevention of cardio‐ and cerebrovascular disease, but for primary prevention it is advised only in…”
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Inappropriate prescription of benzodiazepines in acutely hospitalized older patients
Published in European neuropsychopharmacology (01-07-2019)“…•At hospital discharge, 62% of older patients used benzodiazepines (BDZs) that were inappropriately prescribed.•The inappropriateness of BDZ prescription…”
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Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study
Published in Drugs & aging (01-04-2018)“…Background Among rate-control or rhythm-control strategies, there is conflicting evidence as to which is the best management approach for non-valvular atrial…”
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Implementation of the Frailty Index in hospitalized older patients: Results from the REPOSI register
Published in European journal of internal medicine (01-10-2018)“…Frailty is a state of increased vulnerability to stressors, associated to poor health outcomes. The aim of this study was to design and introduce a Frailty…”
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