Search Results - "Mancuso, Christopher"

PyGenePlexus: a Python package for gene discovery using network-based machine learning by Mancuso, Christopher A, Liu, Renming, Krishnan, Arjun

“…PyGenePlexus is a Python package that enables a user to gain insight into any gene set of interest through a molecular interaction network informed supervised…”
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Precise, automated control of conditions for high-throughput growth of yeast and bacteria with eVOLVER by Wong, Brandon G, Mancuso, Christopher P, Kiriakov, Szilvia, Bashor, Caleb J, Khalil, Ahmad S

“…Continuous culturing of individually controlled growth experiments in parallel and at high-throughput is enabled with an automated DIY platform. Precise…”
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Joint representation of molecular networks from multiple species improves gene classification by Mancuso, Christopher A, Johnson, Kayla A, Liu, Renming, Krishnan, Arjun

“…Network-based machine learning (ML) has the potential for predicting novel genes associated with nearly any health and disease context. However, this approach…”
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Supervised learning is an accurate method for network-based gene classification by Liu, Renming, Mancuso, Christopher A, Yannakopoulos, Anna, Johnson, Kayla A, Krishnan, Arjun

“…Abstract Background Assigning every human gene to specific functions, diseases and traits is a grand challenge in modern genetics. Key to addressing this…”
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A flexible, interpretable, and accurate approach for imputing the expression of unmeasured genes by Mancuso, Christopher A, Canfield, Jacob L, Singla, Deepak, Krishnan, Arjun

“…Abstract While there are >2 million publicly-available human microarray gene-expression profiles, these profiles were measured using a variety of platforms…”
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Helicity-Selective Enhancement and Polarization Control of Attosecond High Harmonic Waveforms Driven by Bichromatic Circularly Polarized Laser Fields by Dorney, Kevin M, Ellis, Jennifer L, Hernández-García, Carlos, Hickstein, Daniel D, Mancuso, Christopher A, Brooks, Nathan, Fan, Tingting, Fan, Guangyu, Zusin, Dmitriy, Gentry, Christian, Grychtol, Patrik, Kapteyn, Henry C, Murnane, Margaret M

“…High harmonics driven by two-color counterrotating circularly polarized laser fields are a unique source of bright, circularly polarized, extreme ultraviolet,…”
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Near- and Extended-Edge X-Ray-Absorption Fine-Structure Spectroscopy Using Ultrafast Coherent High-Order Harmonic Supercontinua by Popmintchev, Dimitar, Galloway, Benjamin R, Chen, Ming-Chang, Dollar, Franklin, Mancuso, Christopher A, Hankla, Amelia, Miaja-Avila, Luis, O'Neil, Galen, Shaw, Justin M, Fan, Guangyu, Ališauskas, Skirmantas, Andriukaitis, Giedrius, Balčiunas, Tadas, Mücke, Oliver D, Pugzlys, Audrius, Baltuška, Andrius, Kapteyn, Henry C, Popmintchev, Tenio, Murnane, Margaret M

“…Recent advances in high-order harmonic generation have made it possible to use a tabletop-scale setup to produce spatially and temporally coherent beams of…”
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GenePlexus: a web-server for gene discovery using network-based machine learning by Mancuso, Christopher A, Bills, Patrick S, Krum, Douglas, Newsted, Jacob, Liu, Renming, Krishnan, Arjun

“…Abstract Biomedical researchers take advantage of high-throughput, high-coverage technologies to routinely generate sets of genes of interest across a wide…”
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A Semi-Quantitative Isothermal Diagnostic Assay Utilizing Competitive Amplification by Mancuso, Christopher P, Lu, Zhi-Xiang, Qian, Jason, Boswell, Sarah A, Springer, Michael

“…Quantitative diagnostics that are rapid, inexpensive, sensitive, robust, and field-deployable are needed to contain the spread of infectious diseases and…”
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Controlling Nonsequential Double Ionization in Two-Color Circularly Polarized Femtosecond Laser Fields by Mancuso, Christopher A, Dorney, Kevin M, Hickstein, Daniel D, Chaloupka, Jan L, Ellis, Jennifer L, Dollar, Franklin J, Knut, Ronny, Grychtol, Patrik, Zusin, Dmitriy, Gentry, Christian, Gopalakrishnan, Maithreyi, Kapteyn, Henry C, Murnane, Margaret M

“…Atoms undergoing strong-field ionization in two-color circularly polarized femtosecond laser fields exhibit unique two-dimensional photoelectron trajectories…”
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Environmental fluctuations reshape an unexpected diversity-disturbance relationship in a microbial community by Mancuso, Christopher P, Lee, Hyunseok, Abreu, Clare I, Gore, Jeff, Khalil, Ahmad S

“…Environmental disturbances have long been theorized to play a significant role in shaping the diversity and composition of ecosystems. However, an inability to…”
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Insufficient evidence for non-neutrality of synonymous mutations by Kruglyak, Leonid, Beyer, Andreas, Bloom, Joshua S., Grossbach, Jan, Lieberman, Tami D., Mancuso, Christopher P., Rich, Matthew S., Sherlock, Gavin, Kaplan, Craig D.

“…[...]the lack of biological replicates in independent growth assays intended to validate competition-based fitness measurements precludes the interpretation…”
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Ultraviolet surprise: Efficient soft x-ray high-harmonic generation in multiply ionized plasmas by Popmintchev, Dimitar, Hernández-García, Carlos, Dollar, Franklin, Mancuso, Christopher, Pérez-Hernández, Jose A., Chen, Ming-Chang, Hankla, Amelia, Gao, Xiaohui, Shim, Bonggu, Gaeta, Alexander L., Tarazkar, Maryam, Romanov, Dmitri A., Levis, Robert J., Gaffney, Jim A., Foord, Mark, Libby, Stephen B., Jaron-Becker, Agnieszka, Becker, Andreas, Plaja, Luis, Murnane, Margaret M., Kapteyn, Henry C., Popmintchev, Tenio

“…High-harmonic generation is a universal response of matter to strong femtosecond laser fields, coherently upconverting light to much shorter wavelengths…”
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Early Circulating Biomarkers of Language Development in Single Ventricle Heart Disease by Wolfe, Kelly R, Thomson, Lindsay M, Niemiec, Sierra, Mancuso, Christopher A, Khailova, Ludmila, Frank, Benjamin S, Davidson, Jesse A

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Real-time reconstruction of high energy, ultrafast laser pulses using deep learning by Stanfield, Matthew, Ott, Jordan, Gardner, Christopher, Beier, Nicholas F., Farinella, Deano M., Mancuso, Christopher A., Baldi, Pierre, Dollar, Franklin

“…We report a method for the phase reconstruction of an ultrashort laser pulse based on the deep learning of the nonlinear spectral changes induce by self-phase…”
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Medical comorbidities and endocrine dysfunction in low‐weight females with avoidant/restrictive food intake disorder compared to anorexia nervosa and healthy controls by Aulinas, Anna, Marengi, Dean A., Galbiati, Francesca, Asanza, Elisa, Slattery, Meghan, Mancuso, Christopher J., Wons, Olivia, Micali, Nadia, Bern, Elana, Eddy, Kamryn T., Thomas, Jennifer J., Misra, Madhusmita, Lawson, Elizabeth A.

“…Objective To improve our understanding of medical complications and endocrine alterations in patients with low‐weight avoidant/restrictive food intake disorder…”
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Mechanisms and time-resolved dynamics for trihydrogen cation (H3+) formation from organic molecules in strong laser fields by Ekanayake, Nagitha, Nairat, Muath, Kaderiya, Balram, Feizollah, Peyman, Jochim, Bethany, Severt, Travis, Berry, Ben, Pandiri, Kanaka Raju, Carnes, Kevin D., Pathak, Shashank, Rolles, Daniel, Rudenko, Artem, Ben-Itzhak, Itzik, Mancuso, Christopher A., Fales, B. Scott, Jackson, James E., Levine, Benjamin G., Dantus, Marcos

“…Strong-field laser-matter interactions often lead to exotic chemical reactions. Trihydrogen cation formation from organic molecules is one such case that…”
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Enhancing nutritional niche and host defenses by modifying the gut microbiome by Sun, Qing, Vega, Nic M, Cervantes, Bernardo, Mancuso, Christopher P, Mao, Ning, Taylor, Megan N, Collins, James J, Khalil, Ahmad S, Gore, Jeff, Lu, Timothy K

“…The gut microbiome is essential for processing complex food compounds and synthesizing nutrients that the host cannot digest or produce, respectively. New…”
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A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance by Newby, Gregory A., Kiriakov, Szilvia, Hallacli, Erinc, Kayatekin, Can, Tsvetkov, Peter, Mancuso, Christopher P., Bonner, J. Maeve, Hesse, William R., Chakrabortee, Sohini, Manogaran, Anita L., Liebman, Susan W., Lindquist, Susan, Khalil, Ahmad S.

“…Protein aggregation is a hallmark of many diseases but also underlies a wide range of positive cellular functions. This phenomenon has been difficult to study…”
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A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities by Hickey, Stephanie L., McKim, Alexander, Mancuso, Christopher A., Krishnan, Arjun

“…Complex diseases are associated with a wide range of cellular, physiological, and clinical phenotypes. To advance our understanding of disease mechanisms and…”
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